Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection JM Dan, J Mateus, Y Kato, KM Hastie, ED Yu, CE Faliti, A Grifoni, ... Science 371 (6529), eabf4063, 2021 | 2807 | 2021 |
A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties K Dooley, RE McConnell, K Xu, ND Lewis, S Haupt, MR Youniss, S Martin, ... Molecular Therapy 29 (5), 1729-1743, 2021 | 159 | 2021 |
Multifaceted effects of antigen valency on B cell response composition and differentiation in vivo Y Kato, RK Abbott, BL Freeman, S Haupt, B Groschel, M Silva, S Menis, ... Immunity 53 (3), 548-563. e8, 2020 | 150 | 2020 |
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity M Silva, Y Kato, MB Melo, I Phung, BL Freeman, Z Li, K Roh, ... Science immunology 6 (66), eabf1152, 2021 | 62 | 2021 |
Exosome surface display of IL12 results in tumor-retained pharmacology with superior potency and limited systemic exposure compared with recombinant IL12 ND Lewis, CL Sia, K Kirwin, S Haupt, G Mahimkar, T Zi, K Xu, K Dooley, ... Molecular cancer therapeutics 20 (3), 523-534, 2021 | 52 | 2021 |
Preparation of therapeutic exosomes using membrane proteins KP Dooley, RA Harrison, RE McConnell, K Xu, DJ Houde, N Ross, ... US Patent 10,561,740, 2020 | 9 | 2020 |
The Chromatin Regulator Mll1 Supports T Follicular Helper Cell Differentiation by Controlling Expression of Bcl6, LEF-1, and TCF-1 S Bélanger, S Haupt, CE Faliti, A Getzler, J Choi, H Diao, ... The Journal of Immunology 210 (11), 1752-1760, 2023 | 3 | 2023 |
The Transcription Factor YY-1 Is an Essential Regulator of T Follicular Helper Cell Differentiation S Bélanger, S Haupt, BL Freeman, AJ Getzler, H Diao, ME Pipkin, S Crotty The Journal of Immunology 209 (8), 1566-1573, 2022 | 3 | 2022 |
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Compositions of Engineered Exosomes and Methods of Loading Luminal Exosome Payloads RE McConnell, KP Dooley, RA Harrison, K Xu, DJ Houde, S Haupt, ... US Patent App. 16/194,230, 2019 | 3 | 2019 |
Compositions of engineered exosomes and methods of loading luminal exosomes pay-loads RE McConnell, KP Dooley, RA Harrison, K Xu, DJ Houde, S Haupt, ... US Patent App. 16/765,116, 2020 | 2 | 2020 |
709 Exosome surface display of IL-12 results in tumor-retained pharmacology with superior potency and limited systemic exposure N Lewis, CL Sia, K Kirwin, S Haupt, G Mahimkar, T Zi, K Xu, K Dooley, ... Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | 2 | 2020 |
Development of a platform for exosome engineering using a novel and selective scaffold protein for surface display K Dooley, K Xu, S Haupt, N Lewis, R Harrison, S Martin, C McCoy, CL Sia, ... | 2 | 2020 |
engEx: A novel exosome engineering platform enabling targeted transfer of pharmacological molecules K Dooley, K Xu, S Haupt, N Lewis, R Harrison, S Martin, C McCoy, CL Sia, ... Proceedings of the American Association for Cancer Research Annual Meeting, 2019 | 2 | 2019 |
Preparation of therapeutic exosomes using membrane proteins KP Dooley, RA Harrison, RE McConnell, K Xu, DJ Houde, N Ross, ... US Patent App. 18/050,005, 2024 | | 2024 |
Compositions of engineered exosomes and methods of loading luminal exosomes pay-loads RE McConnell, KP Dooley, RA Harrison, K Xu, DJ Houde, S Haupt, ... US Patent App. 18/057,709, 2024 | | 2024 |
Engineered extracellular vesicles and uses thereof KP Dooley, RA Harrison, K Xu, DJ Houde, S Haupt, JD Kulman, ... US Patent App. 17/293,833, 2022 | | 2022 |
A Versatile Platform for Precision Exosome Engineering K Dooley, R McConnell, K Xu, S Haupt, M Youniss, S Martin, N Lewis, ... MOLECULAR THERAPY 28 (4), 568-569, 2020 | | 2020 |
Exosome surface display of IL-12 results in tumor-retained pharmacology with superior potency and limited systemic exposure compared to recombinant IL-12 K Kirwin, CL Sia, S Haupt, K Xu, K Dooley, SC Jang, B Choi, A Boutin, ... JOURNAL FOR IMMUNOTHERAPY OF CANCER 7, 2019 | | 2019 |