PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth T Gao, F Furnari, AC Newton Molecular cell 18 (1), 13-24, 2005 | 1130 | 2005 |
PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms J Brognard, E Sierecki, T Gao, AC Newton Molecular cell 25 (6), 917-931, 2007 | 708 | 2007 |
cAMP-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits T Gao, A Yatani, ML Dell'Acqua, H Sako, SA Green, N Dascal, JD Scott, ... Neuron 19 (1), 185-196, 1997 | 674 | 1997 |
mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways P Gulhati, KA Bowen, J Liu, PD Stevens, PG Rychahou, M Chen, EY Lee, ... Cancer research 71 (9), 3246-3256, 2011 | 634 | 2011 |
Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the β2 subunit M Bünemann, BL Gerhardstein, T Gao, MM Hosey Journal of Biological Chemistry 274 (48), 33851-33854, 1999 | 281 | 1999 |
An obligatory role for neurotensin in high-fat-diet-induced obesity J Li, J Song, YY Zaytseva, Y Liu, P Rychahou, K Jiang, ME Starr, JT Kim, ... Nature 533 (7603), 411-415, 2016 | 246 | 2016 |
The phosphatase PHLPP controls the cellular levels of protein kinase C T Gao, J Brognard, AC Newton Journal of Biological Chemistry 283 (10), 6300-6311, 2008 | 229 | 2008 |
Identification and subcellular localization of the subunits of L-type calcium channels and adenylyl cyclase in cardiac myocytes T Gao, TS Puri, BL Gerhardstein, AJ Chien, RD Green, MM Hosey Journal of Biological Chemistry 272 (31), 19401-19407, 1997 | 227 | 1997 |
Adipocytes activate mitochondrial fatty acid oxidation and autophagy to promote tumor growth in colon cancer YA Wen, X Xing, JW Harris, YY Zaytseva, MI Mitov, DL Napier, HL Weiss, ... Cell death & disease 8 (2), e2593-e2593, 2017 | 225 | 2017 |
Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling SM Johnson, PAT Gulhati, I Arrieta, X Wang, T Uchida, T Gao, BM Evers Anticancer research 29 (8), 3185-3190, 2009 | 215 | 2009 |
Collagen prolyl 4-hydroxylase 1 is essential for HIF-1α stabilization and TNBC chemoresistance G Xiong, RL Stewart, J Chen, T Gao, TL Scott, LM Samayoa, K O’Connor, ... Nature communications 9 (1), 4456, 2018 | 203 | 2018 |
Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer P Gulhati, Q Cai, J Li, J Liu, PG Rychahou, S Qiu, EY Lee, SR Silva, ... Clinical cancer research 15 (23), 7207-7216, 2009 | 192 | 2009 |
The turn motif is a phosphorylation switch that regulates the binding of Hsp70 to protein kinase C T Gao, AC Newton Journal of Biological Chemistry 277 (35), 31585-31592, 2002 | 182 | 2002 |
Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer YA Wen, X Xiong, YY Zaytseva, DL Napier, E Vallee, AT Li, C Wang, ... Cell death & disease 9 (3), 265, 2018 | 175 | 2018 |
Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis J Liu, HL Weiss, P Rychahou, LN Jackson, BM Evers, T Gao Oncogene 28 (7), 994-1004, 2009 | 169 | 2009 |
C-terminal fragments of the α1C (CaV1. 2) subunit associate with and regulate L-type calcium channels containing C-terminal-truncated α1CSubunits T Gao, AE Cuadra, H Ma, M Bunemann, BL Gerhardstein, T Cheng, ... Journal of Biological Chemistry 276 (24), 21089-21097, 2001 | 166 | 2001 |
Complexes of the α1C and β subunits generate the necessary signal for membrane targeting of class C L-type calcium channels T Gao, AJ Chien, MM Hosey Journal of Biological Chemistry 274 (4), 2137-2144, 1999 | 165 | 1999 |
Membrane targeting of L-type calcium channels: role of palmitoylation in the subcellular localization of the β2a subunit AJ Chien, T Gao, E Perez-Reyes, MM Hosey Journal of Biological Chemistry 273 (36), 23590-23597, 1998 | 157 | 1998 |
The phosphoinositide-dependent kinase, PDK-1, phosphorylates conventional protein kinase C isozymes by a mechanism that is independent of phosphoinositide 3-kinase ED Sonnenburg, T Gao, AC Newton Journal of Biological Chemistry 276 (48), 45289-45297, 2001 | 155 | 2001 |
Sorcin associates with the pore-forming subunit of voltage-dependent L-type Ca2+ channels MB Meyers, TS Puri, AJ Chien, T Gao, PH Hsu, MM Hosey, GI Fishman Journal of Biological Chemistry 273 (30), 18930-18935, 1998 | 149 | 1998 |