| Structural basis for blocking sugar uptake into the malaria parasite Plasmodium falciparum X Jiang, Y Yuan, J Huang, S Zhang, S Luo, N Wang, D Pu, N Zhao, ... Cell 183 (1), 258-268. e12, 2020 | 48 | 2020 |
| Structural basis for high-voltage activation and subtype-specific inhibition of human Nav1.8 X Huang, X Jin, G Huang, J Huang, T Wu, Z Li, J Chen, F Kong, X Pan, ... Proceedings of the National Academy of Sciences 119 (30), e2208211119, 2022 | 45 | 2022 |
| Cryo-EM structure of human voltage-gated sodium channel Nav1.6 X Fan, J Huang, X Jin, N Yan Proceedings of the National Academy of Sciences 120 (5), e2220578120, 2023 | 26 | 2023 |
| Cannabidiol inhibits Nav channels through two distinct binding sites J Huang, X Fan, X Jin, S Jo, HB Zhang, A Fujita, BP Bean, N Yan Nature Communications 14 (1), 3613, 2023 | 24 | 2023 |
| Structural mapping of Nav1.7 antagonists Q Wu, J Huang, X Fan, K Wang, X Jin, G Huang, J Li, X Pan, N Yan Nature communications 14 (1), 3224, 2023 | 23 | 2023 |
| Orthosteric–allosteric dual inhibitors of PfHT1 as selective antimalarial agents J Huang, Y Yuan, N Zhao, D Pu, Q Tang, S Zhang, S Luo, X Yang, ... Proceedings of the National Academy of Sciences 118 (3), e2017749118, 2021 | 21 | 2021 |
| Rationally designed small-molecule inhibitors targeting an unconventional pocket on the TLR8 protein–protein interface S Jiang, H Tanji, K Yin, S Zhang, K Sakaniwa, J Huang, Y Yang, J Li, ... Journal of Medicinal Chemistry 63 (8), 4117-4132, 2020 | 19 | 2020 |
| Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Cav channels X Yao, S Gao, J Wang, Z Li, J Huang, Y Wang, Z Wang, J Chen, X Fan, ... Cell 185 (25), 4801-4810. e13, 2022 | 13 | 2022 |
| Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a (nta) gonists Y Yang, A Csakai, S Jiang, C Smith, H Tanji, J Huang, T Jones, ... Nature Communications 12 (1), 4351, 2021 | 13 | 2021 |
| 4-Octyl itaconate restricts STING activation by blocking its palmitoylation C Su, T Cheng, J Huang, T Zhang, H Yin Cell reports 42 (9), 2023 | 12 | 2023 |
| Structures of the R-type human Cav2.3 channel reveal conformational crosstalk of the intracellular segments X Yao, Y Wang, Z Wang, X Fan, D Wu, J Huang, A Mueller, S Gao, M Hu, ... Nature communications 13 (1), 7358, 2022 | 12 | 2022 |
| Protein phosphatase 1 regulates phosphorylation of gasdermin D and pyroptosis Y Li, D Pu, J Huang, Y Zhang, H Yin Chemical Communications 58 (85), 11965-11968, 2022 | 11 | 2022 |
| A Candidate Drug Screen Strategy: The Discovery of Oroxylin A in Scutellariae Radix Against Sepsis via the Correlation Analysis Between Plant Metabolomics and … L Han, Y Yuan, X Chen, J Huang, G Wang, C Zhou, J Dong, N Zhang, ... Frontiers in Pharmacology 13, 861105, 2022 | 8 | 2022 |
| Structural basis for human Cav1. 2 inhibition by multiple drugs and the neurotoxin calciseptine S Gao, X Yao, J Chen, G Huang, X Fan, L Xue, Z Li, T Wu, Y Zheng, ... Cell 186 (24), 5363-5374. e16, 2023 | 5 | 2023 |
| Dual-pocket inhibition of Nav channels by the antiepileptic drug lamotrigine J Huang, X Fan, X Jin, L Teng, N Yan Proceedings of the National Academy of Sciences 120 (41), e2309773120, 2023 | 5 | 2023 |
| Switch Off “Parallel Circuit”: Insight of New Strategy of Simultaneously Suppressing Canonical and Noncanonical Inflammation Activation in Endotoxemic Mice L Yan, J Liang, Y Zhou, J Huang, T Zhang, X Wang, H Yin Advanced Biosystems 4 (6), 2000037, 2020 | 5 | 2020 |
| Regulation of aerobic glycolysis to decelerate tumor proliferation by small molecule inhibitors targeting glucose transporters M Gao, J Huang, X Jiang, Y Yuan, H Pang, S Luo, N Wang, C Yao, Z Lin, ... Protein & Cell 11 (6), 446-451, 2020 | 5 | 2020 |
| Structural basis for human Cav3.2 inhibition by selective antagonists J Huang, X Fan, X Jin, C Lyu, Q Guo, T Liu, J Chen, A Davakan, P Lory, ... Cell Research, 1-11, 2024 | 3 | 2024 |
| Photoactivation of innate immunity receptor TLR8 in live mammalian cells by genetic encoding of photocaged tyrosine Y Yang, S Luo, J Huang, Y Xiao, Y Fu, W Liu, H Yin ChemBioChem 23 (4), e202100344, 2022 | 3 | 2022 |
| Development of Complementary Photo‐arginine/lysine to Promote Discovery of Arg/Lys Hptms Interactomes Y Zong, N Weiss, K Wang, AE Pagano, S Heissel, S Perveen, J Huang Advanced Science, 2307526, 2024 | 1 | 2024 |
Nieng YanShenzhen Medical Academy of Research & Translation (SMART) / Tsinghua University / Princeton在 smart.org.cn 的电子邮件经过验证
