Chemically defined conditions for human iPSC derivation and culture G Chen, DR Gulbranson, Z Hou, JM Bolin, V Ruotti, MD Probasco, ... Nature methods 8 (5), 424-429, 2011 | 1689 | 2011 |
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis Z Hou, Y Zhang, NE Propson, SE Howden, LF Chu, EJ Sontheimer, ... Proceedings of the National Academy of Sciences 110 (39), 15644-15649, 2013 | 935 | 2013 |
Epigenomic analysis of multilineage differentiation of human embryonic stem cells W Xie, MD Schultz, R Lister, Z Hou, N Rajagopal, P Ray, JW Whitaker, ... Cell 153 (5), 1134-1148, 2013 | 787 | 2013 |
Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm LF Chu, N Leng, J Zhang, Z Hou, D Mamott, DT Vereide, J Choi, ... Genome biology 17, 1-20, 2016 | 427 | 2016 |
Actin-myosin contractility is responsible for the reduced viability of dissociated human embryonic stem cells G Chen, Z Hou, DR Gulbranson, JA Thomson Cell stem cell 7 (2), 240-248, 2010 | 354 | 2010 |
Human pluripotent stem cell-derived neural constructs for predicting neural toxicity MP Schwartz, Z Hou, NE Propson, J Zhang, CJ Engstrom, VS Costa, ... Proceedings of the National Academy of Sciences 112 (40), 12516-12521, 2015 | 350 | 2015 |
Introducing a spectrum of long-range genomic deletions in human embryonic stem cells using type I CRISPR-Cas AE Dolan, Z Hou, Y Xiao, MJ Gramelspacher, J Heo, SE Howden, ... Molecular cell 74 (5), 936-950. e5, 2019 | 170 | 2019 |
Dynamics of PARKIN-dependent mitochondrial ubiquitylation in induced neurons and model systems revealed by digital snapshot proteomics A Ordureau, JA Paulo, W Zhang, T Ahfeldt, J Zhang, EF Cohn, Z Hou, ... Molecular cell 70 (2), 211-227. e8, 2018 | 162 | 2018 |
Thermal stability of fibroblast growth factor protein is a determinant factor in regulating self-renewal, differentiation, and reprogramming in human pluripotent stem cells G Chen, DR Gulbranson, P Yu, Z Hou, JA Thomson Stem cells 30 (4), 623-630, 2012 | 149 | 2012 |
Functional characterization of human pluripotent stem cell-derived arterial endothelial cells J Zhang, LF Chu, Z Hou, MP Schwartz, T Hacker, V Vickerman, ... Proceedings of the National Academy of Sciences 114 (30), E6072-E6078, 2017 | 148 | 2017 |
Rna-directed dna cleavage and gene editing by cas9 enzyme from neisseria meningitidis EJ Sontheimer, Y Zhang, A Mondragon, R Rajan, J Thomson, ... | 135 | 2014 |
A cost-effective RNA sequencing protocol for large-scale gene expression studies Z Hou, P Jiang, SA Swanson, AL Elwell, BKS Nguyen, JM Bolin, ... Scientific reports 5 (1), 9570, 2015 | 115 | 2015 |
Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels MR Zanotelli, H Ardalani, J Zhang, Z Hou, EH Nguyen, S Swanson, ... Acta biomaterialia 35, 32-41, 2016 | 107 | 2016 |
Phosphorylation regulates human OCT4 J Brumbaugh, Z Hou, JD Russell, SE Howden, P Yu, AR Ledvina, ... Proceedings of the national academy of sciences 109 (19), 7162-7168, 2012 | 104 | 2012 |
Structural basis of the Sir1–origin recognition complex interaction in transcriptional silencing Z Hou, DA Bernstein, CA Fox, JL Keck Proceedings of the National Academy of Sciences 102 (24), 8489-8494, 2005 | 100 | 2005 |
Programmable RNA cleavage and recognition by a natural CRISPR-Cas9 system from Neisseria meningitidis BA Rousseau, Z Hou, MJ Gramelspacher, Y Zhang Molecular cell 69 (5), 906-914. e4, 2018 | 96 | 2018 |
Integrated module and gene-specific regulatory inference implicates upstream signaling networks S Roy, S Lagree, Z Hou, JA Thomson, R Stewart, AP Gasch PLoS computational biology 9 (10), e1003252, 2013 | 87 | 2013 |
MPBind: a Meta-motif-based statistical framework and pipeline to Predict Binding potential of SELEX-derived aptamers P Jiang, S Meyer, Z Hou, NE Propson, HT Soh, JA Thomson, R Stewart Bioinformatics 30 (18), 2665-2667, 2014 | 66 | 2014 |
Characterization and target identification of a DNA aptamer that labels pluripotent stem cells Z Hou, S Meyer, NE Propson, J Nie, P Jiang, R Stewart, JA Thomson Cell research 25 (3), 390-393, 2015 | 65 | 2015 |
Cas11 enables genome engineering in human cells with compact CRISPR-Cas3 systems R Tan, RK Krueger, MJ Gramelspacher, X Zhou, Y Xiao, A Ke, Z Hou, ... Molecular cell 82 (4), 852-867. e5, 2022 | 55 | 2022 |