ZDOCK: an initial‐stage protein‐docking algorithm R Chen, L Li, Z Weng Proteins: Structure, Function, and Bioinformatics 52 (1), 80-87, 2003 | 1640 | 2003 |
Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes R Chen, GI Mias, J Li-Pook-Than, L Jiang, HYK Lam, R Chen, E Miriami, ... Cell 148 (6), 1293-1307, 2012 | 1380 | 2012 |
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. L Shi, G Campbell, WD Jones, F Campagne, Z Wen, SJ Walker, Z Su, ... Nature biotechnology 28 (8), 827, 2010 | 854 | 2010 |
A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium. SMIII Consortium. Nature Biotechnology 32 (9), 903-914, 2014 | 846 | 2014 |
AKI in hospitalized patients with COVID-19 L Chan, K Chaudhary, A Saha, K Chauhan, A Vaid, S Zhao, I Paranjpe, ... Journal of the American Society of Nephrology 32 (1), 151-160, 2021 | 827 | 2021 |
Clinical assessment incorporating a personal genome EA Ashley, AJ Butte, MT Wheeler, R Chen, TE Klein, FE Dewey, ... The Lancet 375 (9725), 1525-1535, 2010 | 807 | 2010 |
Identification of type 2 diabetes subgroups through topological analysis of patient similarity L Li, WY Cheng, BS Glicksberg, O Gottesman, R Tamler, R Chen, ... Science translational medicine 7 (311), 311ra174-311ra174, 2015 | 610 | 2015 |
Performance comparison of exome DNA sequencing technologies MJ Clark, R Chen, HYK Lam, KJ Karczewski, R Chen, G Euskirchen, ... Nature Biotechnology, 2011 | 591 | 2011 |
Docking unbound proteins using shape complementarity, desolvation, and electrostatics R Chen, Z Weng Proteins: Structure, Function, and Bioinformatics 47 (3), 281-294, 2002 | 485 | 2002 |
Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets S Suthram, JT Dudley, AP Chiang, R Chen, TJ Hastie, AJ Butte PLoS computational biology 6 (2), e1000662, 2010 | 385 | 2010 |
RDOCK: refinement of rigid‐body protein docking predictions L Li, R Chen, Z Weng Proteins: Structure, Function, and Bioinformatics 53 (3), 693-707, 2003 | 384 | 2003 |
Integrating statistical pair potentials into protein complex prediction J Mintseris, B Pierce, K Wiehe, R Anderson, R Chen, Z Weng Proteins: Structure, Function, and Bioinformatics 69 (3), 511-520, 2007 | 375 | 2007 |
Protein–protein docking benchmark 2.0: an update J Mintseris, K Wiehe, B Pierce, R Anderson, R Chen, J Janin, Z Weng Proteins: Structure, Function, and Bioinformatics 60 (2), 214-216, 2005 | 369 | 2005 |
A novel shape complementarity scoring function for protein‐protein docking R Chen, Z Weng Proteins: Structure, Function, and Bioinformatics 51 (3), 397-408, 2003 | 367 | 2003 |
Performance comparison of whole-genome sequencing platforms HYK Lam, MJ Clark, R Chen, R Chen, G Natsoulis, M O'Huallachain, ... Nature Biotechnology, 2011 | 361 | 2011 |
A protein–protein docking benchmark R Chen, J Mintseris, J Janin, Z Weng Proteins: Structure, Function, and Bioinformatics 52 (1), 88-91, 2003 | 358 | 2003 |
Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases R Chen, L Shi, J Hakenberg, B Naughton, P Sklar, J Zhang, H Zhou, ... Nature biotechnology 34 (5), 531-538, 2016 | 355 | 2016 |
Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum–associated degradation pathway GM Enns, V Shashi, M Bainbridge, MJ Gambello, FR Zahir, T Bast, ... Genetics in Medicine 16 (10), 751-758, 2014 | 230 | 2014 |
Non-synonymous and synonymous coding SNPs show similar likelihood and effect size of human disease association R Chen, EV Davydov, M Sirota, AJ Butte PloS one 5 (10), e13574, 2010 | 212 | 2010 |
Acute Intermittent Porphyria: Predicted Pathogenicity of HMBS Variants Indicates Extremely Low Penetrance of the Autosomal Dominant Disease B Chen, C Solis‐Villa, J Hakenberg, W Qiao, RR Srinivasan, M Yasuda, ... Human mutation 37 (11), 1215-1222, 2016 | 188 | 2016 |