Synovial tissue from sites of joint pain in knee osteoarthritis patients exhibits a differential phenotype with distinct fibroblast subsets DE Nanus, A Badoume, SN Wijesinghe, AM Halsey, P Hurley, Z Ahmed, ... EBioMedicine 72, 2021 | 78 | 2021 |
Regulation of the inflammatory synovial fibroblast phenotype by metastasis‐associated lung adenocarcinoma transcript 1 long noncoding RNA in obese patients with osteoarthritis DE Nanus, SN Wijesinghe, MJ Pearson, MR Hadjicharalambous, ... Arthritis & rheumatology 72 (4), 609-619, 2020 | 62 | 2020 |
Involvements of long noncoding RNAs in obesity‐associated inflammatory diseases SN Wijesinghe, T Nicholson, K Tsintzas, SW Jones Obesity reviews 22 (4), e13156, 2021 | 43 | 2021 |
A novel form of JARID2 is required for differentiation in lineage‐committed cells D Al‐Raawi, R Jones, S Wijesinghe, J Halsall, M Petric, S Roberts, ... The EMBO journal 38 (3), e98449, 2019 | 24 | 2019 |
Differential metabotypes in synovial fibroblasts and synovial fluid in hip osteoarthritis patients support inflammatory responses H Farah, SN Wijesinghe, T Nicholson, F Alnajjar, M Certo, A Alghamdi, ... International journal of molecular sciences 23 (6), 3266, 2022 | 22 | 2022 |
Obesity defined molecular endotypes in the synovium of patients with osteoarthritis provides a rationale for therapeutic targeting of fibroblast subsets SN Wijesinghe, A Badoume, DE Nanus, A Sharma‐Oates, H Farah, ... Clinical and Translational Medicine 13 (4), e1232, 2023 | 19 | 2023 |
Oligonucleotide therapies in the treatment of arthritis: a narrative review SN Wijesinghe, MA Lindsay, SW Jones Biomedicines 9 (8), 902, 2021 | 15 | 2021 |
A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1 R Jones, S Wijesinghe, C Wilson, J Halsall, T Liloglou, A Kanhere Iscience 24 (4), 2021 | 11 | 2021 |
The expression and function of metastases associated lung adenocarcinoma transcript-1 long non-coding RNA in subchondral bone and osteoblasts from patients with osteoarthritis FA Alnajjar, A Sharma-Oates, SN Wijesinghe, H Farah, DE Nanus, ... Cells 10 (4), 786, 2021 | 9 | 2021 |
Synovial tissue from sites of joint pain in knee osteoarthritis patients exhibits a differential phenotype with distinct fibroblast subsets. eBioMedicine 2021; 72, 103618 DE Nanus, A Badoume, SN Wijesinghe, AM Halsey, P Hurley, Z Ahmed, ... Annals of Translational Medicine. All rights reserved. https://dx. doi. org …, 2021 | 8 | 2021 |
Novel gene variants in patients with platelet‐based bleeding using combined exome sequencing and RNAseq murine expression data AO Khan, RJ Stapley, JA Pike, SN Wijesinghe, JS Reyat, I Almazni, ... Journal of Thrombosis and Haemostasis 19 (1), 262-268, 2021 | 7 | 2021 |
The role of extracellular vesicle miRNAs and tRNAs in synovial fibroblast senescence SN Wijesinghe, J Anderson, TJ Brown, DE Nanus, B Housmans, ... Frontiers in Molecular Biosciences 9, 971621, 2022 | 6 | 2022 |
Oligonucleotide therapeutics for age-related musculoskeletal disorders: Successes and challenges TA Nicholson, M Sagmeister, SN Wijesinghe, H Farah, RS Hardy, ... Pharmaceutics 15 (1), 237, 2023 | 4 | 2023 |
Long Non-coding RNAs in Rheumatology SN Wijesinghe, MA Lindsay, SW Jones Long Noncoding RNA: Mechanistic Insights and Roles in Inflammation, 35-70, 2022 | 3 | 2022 |
Oligonucleotide therapies in the treatment of inflammatory joint disease SN Wijesinghe, MA Lindsay, SW Jones Preprints, 2021 | 2 | 2021 |
Obese synovial fibroblasts exhibit single cell subsets with specific pathological inflammatory functions in osteoarthritis patients SN Wijesinghe, A Badoume, DE Nanus, ET Davis, MA Lindsay, SW Jones Osteoarthritis and Cartilage 28, S84, 2020 | 2 | 2020 |
Oligonucleotide Therapeutics for Age-Related Musculoskeletal Disorders TA Nicholson, M Sagmeister, SN Wijesinghe, H Farah, RS Hardy, ... | 1 | 2023 |
Identification of synovial fibroblasts subsets associated with pain and progression of knee osteoarthritis by single cell sequencing DE Nanus, A Badoume, SN Wijesinghe, P Hurley, ET Davis, MA Lindsay, ... Osteoarthritis and Cartilage 28, S133, 2020 | 1 | 2020 |
The combination of local infiltration analgesia reagents increases their detrimental effect on human hip OA patient osteoblast viability and function P Hurley, F Alnajjar, S Wijesinghe, DE Nanus, ET Davis, SW Jones Journal of Orthopaedics 16 (5), 434-439, 2019 | 1 | 2019 |
Immunomodulation and fibroblast dynamics driving nociceptive joint pain within inflammatory synovium: Unravelling Mechanisms for Therapeutic Advancements in Osteoarthritis SN Wijesinghe, C Ditchfield, S Flynn, J Agrawal, ET Davis, ... Osteoarthritis and Cartilage, 2024 | | 2024 |