A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism M Davidsson, G Wang, P Aldrin-Kirk, T Cardoso, S Nolbrant, M Hartnor, ... Proceedings of the National Academy of Sciences 116 (52), 27053-27062, 2019 | 149 | 2019 |
A novel process of viral vector barcoding and library preparation enables high-diversity library generation and recombination-free paired-end sequencing M Davidsson, P Diaz-Fernandez, OD Schwich, M Torroba, G Wang, ... Scientific Reports 6 (1), 37563, 2016 | 57 | 2016 |
Chemogenetic modulation of cholinergic interneurons reveals their regulating role on the direct and indirect output pathways from the striatum P Aldrin-Kirk, A Heuer, DR Ottosson, M Davidsson, B Mattsson, ... Neurobiology of disease 109, 148-162, 2018 | 49 | 2018 |
AAV production everywhere: a simple, fast, and reliable protocol for in‐house AAV vector production based on chloroform extraction M Negrini, G Wang, A Heuer, T Björklund, M Davidsson Current protocols in neuroscience 93 (1), e103, 2020 | 47 | 2020 |
Novel AAV-based rat model of forebrain synucleinopathy shows extensive pathologies and progressive loss of cholinergic interneurons P Aldrin-Kirk, M Davidsson, S Holmqvist, JY Li, T Björklund PLoS One 9 (7), e100869, 2014 | 40 | 2014 |
Skeletal Muscle Atrophy in R6/2 Mice–Altered Circulating Skeletal Muscle Markers and Gene Expression Profile Changes A Magnusson-Lind, M Davidsson, E Silajdžić, C Hansen, AC McCourt, ... Journal of Huntington's disease 3 (1), 13-24, 2014 | 28 | 2014 |
A comparison of AAV-vector production methods for gene therapy and preclinical assessment M Davidsson, M Negrini, S Hauser, A Svanbergsson, M Lockowandt, ... Scientific reports 10 (1), 21532, 2020 | 26 | 2020 |
Destabilizing domains enable long-term and inert regulation of GDNF expression in the brain L Quintino, A Namislo, M Davidsson, LS Breger, P Kavanagh, M Avallone, ... Molecular Therapy-Methods & Clinical Development 11, 29-39, 2018 | 22 | 2018 |
Sequential or simultaneous injection of preformed fibrils and AAV overexpression of alpha-synuclein are equipotent in producing relevant pathology and behavioral deficits M Negrini, G Tomasello, M Davidsson, A Fenyi, C Adant, S Hauser, ... Journal of Parkinson's disease 12 (4), 1133-1153, 2022 | 19 | 2022 |
Next-generation gene therapy for parkinson’s disease using engineered viral vectors T Björklund, M Davidsson Journal of Parkinson's Disease 11 (s2), S209-S217, 2021 | 12 | 2021 |
Lateralized deficits after unilateral AAV-vector based overexpression of alpha-synuclein in the midbrain of rats on drug-free behavioral tests F Gubinelli, G Cazzolla, M Negrini, I Kulacz, A Mehrdadian, G Tomasello, ... Behavioural Brain Research 429, 113887, 2022 | 10 | 2022 |
Characterisation of functional deficits induced by AAV overexpression of alpha-synuclein in rats F Gubinelli, L Sarauskyte, C Venuti, I Kulacz, G Cazzolla, M Negrini, ... Current Research in Neurobiology 4, 100065, 2023 | 8 | 2023 |
A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants P Aldrin-Kirk, M Åkerblom, T Cardoso, S Nolbrant, AF Adler, X Liu, ... Stem Cell Reports 17 (1), 159-172, 2022 | 7 | 2022 |
Barcoded Rational AAV Vector Evolution enables systematic in vivo mapping of peptide binding motifs M Davidsson, G Wang, P Aldrin-Kirk, T Cardoso, S Nolbrant, M Hartnor, ... bioRxiv, 335372, 2018 | 7 | 2018 |
Molecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing M Davidsson, P Díaz-Fernández, M Torroba, OD Schwich, P Aldrin-Kirk, ... Rna 24 (5), 673-687, 2018 | 6 | 2018 |
Visualizing Arc protein dynamics and localization in the mammalian brain using AAV-mediated in situ gene labeling M Avallone, J Pardo, TF Mergiya, J Rájová, A Räsänen, M Davidsson, ... Frontiers in Molecular Neuroscience 16, 1140785, 2023 | 4 | 2023 |
Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants in vivo J Rájová, M Davidsson, M Avallone, M Hartnor, P Aldrin-Kirk, T Cardoso, ... Molecular Therapy Methods & Clinical Development 29, 381-394, 2023 | 3 | 2023 |
A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates DM Anwer, F Gubinelli, YA Kurt, L Sarauskyte, F Jacobs, C Venuti, ... Plos one 18 (5), e0284480, 2023 | 3 | 2023 |
Automated quantification of neuronal swellings in a preclinical rodent model of Parkinson’s disease detects region-specific changes in pathology L Quintino, F Gubinelli, L Sarauskyte, E Arvidsson, M Davidsson, ... Journal of Neuroscience Methods 378, 109640, 2022 | 3 | 2022 |
Small scale adeno-associated virus-vector production for preclinical gene delivery based on chloroform precipitation M Davidsson, A Heuer Neural Regeneration Research 17 (1), 99-100, 2022 | 2 | 2022 |