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Umang Jain
Umang Jain
Washington university st Louis
在 dal.ca 的电子邮件经过验证
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The microbial metabolite desaminotyrosine protects from influenza through type I interferon
AL Steed, GP Christophi, GE Kaiko, L Sun, VM Goodwin, U Jain, ...
Science 357 (6350), 498-502, 2017
4702017
Debaryomyces is enriched in Crohn’s disease intestinal tissue and impairs healing in mice
U Jain, AM Ver Heul, S Xiong, MH Gregory, EG Demers, JT Kern, CW Lai, ...
Science 371 (6534), 1154-1159, 2021
1612021
Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation
TC Liu, JT Kern, U Jain, NM Sonnek, S Xiong, KF Simpson, ...
Cell host & microbe 29 (6), 988-1001. e6, 2021
1002021
Do antimicrobial peptides and complement collaborate in the intestinal mucosa?
ZA Kopp, U Jain, J Van Limbergen, AW Stadnyk
Frontiers in immunology 6, 17, 2015
742015
The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL‐4 and IL‐10
U Jain, TM Woodruff, AW Stadnyk
British journal of pharmacology 168 (2), 488-501, 2013
742013
PAI-1 augments mucosal damage in colitis
GE Kaiko, F Chen, CW Lai, IL Chiang, J Perrigoue, A Stojmirović, K Li, ...
Science translational medicine 11 (482), eaat0852, 2019
652019
The complement system in inflammatory bowel disease
U Jain, AR Otley, J Van Limbergen, AW Stadnyk
Inflammatory bowel diseases 20 (9), 1628-1637, 2014
562014
Temporal regulation of the bacterial metabolite deoxycholate during colonic repair is critical for crypt regeneration
U Jain, CW Lai, S Xiong, VM Goodwin, Q Lu, BD Muegge, GP Christophi, ...
Cell host & microbe 24 (3), 353-363. e5, 2018
552018
Properdin provides protection from citrobacter rodentium–induced intestinal inflammation in a C5a/IL-6–dependent manner
U Jain, Q Cao, NA Thomas, TM Woodruff, WJ Schwaeble, CM Stover, ...
The Journal of Immunology 194 (7), 3414-3421, 2015
262015
Reverse translation approach generates a signature of penetrating fibrosis in Crohn’s disease that is associated with anti-TNF response
S Xiong, CE Whitehurst, L Li, GS Heo, CW Lai, U Jain, BD Muegge, ...
Gut 71 (7), 1289-1301, 2022
172022
Properdin Regulation of Complement Activation Affects Colitis in Interleukin 10 Gene–Deficient Mice
U Jain, CA Midgen, WJ Schwaeble, CM Stover, AW Stadnyk
Inflammatory bowel diseases 21 (7), 1519-1528, 2015
152015
Properdin deficiency protects from 5-fluorouracil-induced small intestinal mucositis in a complement activation-independent, interleukin-10-dependent mechanism
U Jain, CA Midgen, TM Woodruff, WJ Schwaeble, CM Stover, AW Stadnyk
Clinical & Experimental Immunology 188 (1), 36-44, 2017
142017
Tandem tyrosine phosphosites in the Enteropathogenic Escherichia coli chaperone CesT are required for differential type III effector translocation and virulence
CS Runte, U Jain, LJ Getz, S Secord, A Kuwae, A Abe, JJ LeBlanc, ...
Molecular Microbiology 108 (5), 536-550, 2018
112018
Erdheim-Chester Disease presenting with histiocytic colitis and cytokine storm.
GP Christophi, Y Sharma, Q Farhan, U Jain, T Walker, GS Sayuk, ...
Journal of Gastrointestinal & Liver Diseases 26 (2), 2017
72017
Oxylipins and metabolites from pyroptotic cells act as promoters of tissue repair
P Mehrotra, S Maschalidi, L Boeckaerts, C Maueröder, R Tixeira, J Pinney, ...
Nature, 1-9, 2024
32024
NAD+ precursors and bile acid sequestration treat preclinical refractory environmental enteric dysfunction
A Malique, S Sun, K Chandwe, B Amadi, T Haritunians, U Jain, ...
Science translational medicine 16 (728), eabq4145, 2024
12024
INSIGHTS INTO THE ROLE OF COMPLEMENT DURING INTESTINAL INFLAMMATION
U Jain
2016
Properdin mediates complement activation and is protective against infectious colitis (902.6)
U Jain, N Thomas, C Stover, A Stadnyk
The FASEB Journal 28, 902.6, 2014
2014
Antagonizing C5aR reduces T Cell-IL-10-dependent colitis in pre-clinical models
U Jain, T Woodruff, A Stadnyk
Inflammatory Bowel Diseases 18 (Supplement 1), S110-S110, 2012
2012
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