| Cutaneous Na+ storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense J Jantsch, V Schatz, D Friedrich, A Schröder, C Kopp, I Siegert, ... Cell metabolism 21 (3), 493-501, 2015 | 361 | 2015 |
| Parameter estimation using simulated annealing for S-system models of biochemical networks OR Gonzalez, C Küper, K Jung, PC Naval Jr, E Mendoza Bioinformatics 23 (4), 480-486, 2007 | 198 | 2007 |
| Renal sodium gradient orchestrates a dynamic antibacterial defense zone MR Berry, RJ Mathews, JR Ferdinand, C Jing, KW Loudon, E Wlodek, ... Cell 170 (5), 860-874. e19, 2017 | 151 | 2017 |
| CadC-Mediated Activation of the cadBA Promoter in Escherichia coli C Küper, K Jung Journal of molecular microbiology and biotechnology 10 (1), 26-39, 2005 | 111 | 2005 |
| Toll-like receptor 4 activates NF-κB and MAP kinase pathways to regulate expression of proinflammatory COX-2 in renal medullary collecting duct cells C Küper, FX Beck, W Neuhofer American Journal of Physiology-Renal Physiology 302 (1), F38-F46, 2012 | 94 | 2012 |
| NFAT5-mediated expression of S100A4 contributes to proliferation and migration of renal carcinoma cells C Küper, FX Beck, W Neuhofer Frontiers in physiology 5, 293, 2014 | 75 | 2014 |
| LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding HH Lee, S Sanada, SM An, BJ Ye, JH Lee, YK Seo, C Lee, W Lee-Kwon, ... Scientific reports 6 (1), 24921, 2016 | 62 | 2016 |
| A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes I Serr, MG Scherm, AM Zahm, J Schug, VK Flynn, M Hippich, S Kälin, ... Science Translational Medicine 10 (422), eaag1782, 2018 | 60 | 2018 |
| Osmoadaptation of Mammalian cells-an orchestrated network of protective genes C Kuper, FX Beck, W Neuhofer Current genomics 8 (4), 209-218, 2007 | 59 | 2007 |
| PGE2 potentiates tonicity-induced COX-2 expression in renal medullary cells in a positive feedback loop involving EP2-cAMP-PKA signaling D Steinert, C Küper, H Bartels, FX Beck, W Neuhofer American Journal of Physiology-Cell Physiology 296 (1), C75-C87, 2009 | 52 | 2009 |
| NFAT5 Contributes to Osmolality‐Induced MCP‐1 Expression in Mesothelial Cells C Küper, FX Beck, W Neuhofer Mediators of inflammation 2012 (1), 513015, 2012 | 37 | 2012 |
| Generation of a conditional knockout allele for the NFAT5 gene in mice C Küper, FX Beck, W Neuhofer Frontiers in physiology 5, 507, 2015 | 34 | 2015 |
| Autocrine MCP-1/CCR2 signaling stimulates proliferation and migration of renal carcinoma cells C Küper, FX Beck, W Neuhofer Oncology Letters 12 (3), 2201-2209, 2016 | 32 | 2016 |
| Sepsis-induced urinary concentration defect is related to nitric oxide–dependent inactivation of TonEBP/NFAT5, which downregulates renal medullary solute transport proteins and … C Küper, ML Fraek, HH Müller, FX Beck, W Neuhofer Critical care medicine 40 (6), 1887-1895, 2012 | 27 | 2012 |
| EGF receptor signaling is involved in expression of osmoprotective TonEBP target gene aldose reductase under hypertonic conditions C Küper, D Steinert, ML Fraek, FX Beck, W Neuhofer American Journal of Physiology-Renal Physiology 296 (5), F1100-F1108, 2009 | 26 | 2009 |
| Ectodomain shedding of pro-TGF-α is required for COX-2 induction and cell survival in renal medullary cells exposed to osmotic stress C Kuper, H Bartels, ML Fraek, FX Beck, W Neuhofer American Journal of Physiology-Cell Physiology 293 (6), C1971-C1982, 2007 | 26 | 2007 |
| Cyclooxygenase-2-dependent phosphorylation of the pro-apoptotic protein Bad inhibits tonicity-induced apoptosis in renal medullary cells C Küper, H Bartels, FX Beck, W Neuhofer Kidney international 80 (9), 938-945, 2011 | 21 | 2011 |
| Focal adhesion kinase regulates the activity of the osmosensitive transcription factor TonEBP/NFAT5 under hypertonic conditions W Neuhofer, C Küper, J Lichtnekert, K Holzapfel, KV Rupanagudi, ... Frontiers in Physiology 5, 123, 2014 | 14 | 2014 |
| Dual effect of lithium on NFAT5 activity in kidney cells C Küper, FX Beck, W Neuhofer Frontiers in Physiology 6, 264, 2015 | 6 | 2015 |
| The role of the osmosensitive transcription factor NFAT5 in corneal edema resorption after injury K Hadrian, G Musial, A Schönberg, T Georgiev, C Küper, F Bock, ... Experimental & Molecular Medicine 55 (3), 565-573, 2023 | 3 | 2023 |
