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David G. McFadden
David G. McFadden
Associate Professor of Internal Medicine, UT Southwestern Medical Center
在 utsouthwestern.edu 的电子邮件经过验证 - 首页
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Integrated genomic characterization of papillary thyroid carcinoma
N Agrawal, R Akbani, BA Aksoy, A Ally, H Arachchi, SL Asa, JT Auman, ...
Cell 159 (3), 676-690, 2014
25932014
Thyroid cancer
ME Cabanillas, DG McFadden, C Durante
The Lancet 388 (10061), 2783-2795, 2016
14342016
Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1
AB Firulli, DG McFadden, Q Lin, D Srivastava, EN Olson
Nature genetics 18 (3), 266-270, 1998
4391998
The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner
DG McFadden, AC Barbosa, JA Richardson, MD Schneider, D Srivastava, ...
Development 132 (1), 189-201, 2005
3982005
Redifferentiation of iodine-refractory BRAF V600E-mutant metastatic papillary thyroid cancer with dabrafenib
SM Rothenberg, DG McFadden, EL Palmer, GH Daniels, LJ Wirth
Clinical Cancer Research 21 (5), 1028-1035, 2015
3452015
Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing
DG McFadden, T Papagiannakopoulos, A Taylor-Weiner, C Stewart, ...
Cell 156 (6), 1298-1311, 2014
3042014
Members of the HRT family of basic helix–loop–helix proteins act as transcriptional repressors downstream of Notch signaling
O Nakagawa, DG McFadden, M Nakagawa, H Yanagisawa, T Hu, ...
Proceedings of the National Academy of Sciences 97 (25), 13655-13660, 2000
2952000
The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development
J Charité, DG McFadden, EN Olson
Development 127 (11), 2461-2470, 2000
2822000
Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma
RK Gopal, K Kübler, SE Calvo, P Polak, D Livitz, D Rosebrock, PM Sadow, ...
Cancer cell 34 (2), 242-255. e5, 2018
2212018
Small Cell Lung Cancer: Can recent advances in biology and molecular biology be translated into improved outcomes?
PA Bunn, JD Minna, A Augustyn, AF Gazdar, Y Ouadah, MA Krasnow, ...
Journal of Thoracic Oncology 11 (4), 453-474, 2016
2052016
Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma
DG McFadden, K Politi, A Bhutkar, FK Chen, X Song, M Pirun, ...
Proceedings of the National Academy of Sciences 113 (42), E6409-E6417, 2016
1932016
A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart
DG McFadden, J Charité, JA Richardson, D Srivastava, AB Firulli, ...
Development 127 (24), 5331-5341, 2000
1852000
p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer
DG McFadden, A Vernon, PM Santiago, R Martinez-McFaline, A Bhutkar, ...
Proceedings of the National Academy of Sciences 111 (16), E1600-E1609, 2014
1802014
Role of Dlx6 in regulation of an endothelin-1-dependent, dHAND branchial arch enhancer
J Charité, DG McFadden, G Merlo, G Levi, DE Clouthier, M Yanagisawa, ...
Genes & development 15 (22), 3039-3049, 2001
1632001
Misexpression of dHAND induces ectopic digits in the developing limb bud in the absence of direct DNA binding
DG McFadden, J McAnally, JA Richardson, J Charité, EN Olson
Development 129 (13), 3077-3088, 2002
1182002
The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung
AF Gazdar, TK Savage, JE Johnson, A Berns, J Sage, RI Linnoila, ...
Journal of Thoracic Oncology 10 (4), 553-564, 2015
1152015
Identification of oncogenic mutations and gene fusions in the follicular variant of papillary thyroid carcinoma
DG McFadden, D Dias-Santagata, PM Sadow, KD Lynch, C Lubitz, ...
The Journal of Clinical Endocrinology & Metabolism 99 (11), E2457-E2462, 2014
692014
Heart development: learning from mistakes
DG McFadden, EN Olson
Current opinion in genetics & development 12 (3), 328-335, 2002
692002
Gα q and Gα 11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme
K Ivey, B Tyson, P Ukidwe, DG McFadden, G Levi, EN Olson, D Srivastava, ...
Developmental biology 255 (2), 230-237, 2003
662003
Combined BRAFV600E-and SRC-inhibition induces apoptosis, evokes an immune response and reduces tumor growth in an immunocompetent orthotopic mouse model of anaplastic thyroid …
PV Borre, V Gunda, DG McFadden, PM Sadow, S Varmeh, M Bernasconi, ...
Oncotarget 5 (12), 3996, 2014
552014
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