| Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth T Hitosugi, S Kang, MG Vander Heiden, TW Chung, S Elf, K Lythgoe, ... Science signaling 2 (97), ra73-ra73, 2009 | 847 | 2009 |
| p53 regulates hematopoietic stem cell quiescence Y Liu, SE Elf, Y Miyata, G Sashida, Y Liu, G Huang, S Di Giandomenico, ... Cell stem cell 4 (1), 37-48, 2009 | 641 | 2009 |
| Distinctive and indispensable roles of PU. 1 in maintenance of hematopoietic stem cells and their differentiation H Iwasaki, C Somoza, H Shigematsu, EA Duprez, J Iwasaki-Arai, ... Blood 106 (5), 1590-1600, 2005 | 546 | 2005 |
| Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth T Hitosugi, L Zhou, S Elf, J Fan, HB Kang, JH Seo, C Shan, Q Dai, ... Cancer cell 22 (5), 585-600, 2012 | 432 | 2012 |
| PU. 1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis G Huang, P Zhang, H Hirai, S Elf, X Yan, Z Chen, S Koschmieder, ... Nature genetics 40 (1), 51-60, 2008 | 296 | 2008 |
| Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex J Fan, C Shan, HB Kang, S Elf, J Xie, M Tucker, TL Gu, M Aguiar, ... Molecular cell 53 (4), 534-548, 2014 | 292 | 2014 |
| Mutant calreticulin requires both its mutant C-terminus and the thrombopoietin receptor for oncogenic transformation S Elf, NS Abdelfattah, E Chen, J Perales-Patón, EA Rosen, A Ko, ... Cancer discovery 6 (4), 368-381, 2016 | 272 | 2016 |
| 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling R Lin, S Elf, C Shan, HB Kang, Q Ji, L Zhou, T Hitosugi, L Zhang, S Zhang, ... Nature cell biology 17 (11), 1484-1496, 2015 | 267 | 2015 |
| Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation J Wang, C Luo, C Shan, Q You, J Lu, S Elf, Y Zhou, Y Wen, JL Vinkenborg, ... Nature chemistry 7 (12), 968-979, 2015 | 229 | 2015 |
| p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells S Kang, S Elf, K Lythgoe, T Hitosugi, J Taunton, W Zhou, L Xiong, D Wang, ... The Journal of clinical investigation 120 (4), 1165-1177, 2010 | 180 | 2010 |
| Metabolic rewiring by oncogenic BRAF V600E links ketogenesis pathway to BRAF-MEK1 signaling HB Kang, J Fan, R Lin, S Elf, Q Ji, L Zhao, L Jin, JH Seo, C Shan, ... Molecular cell 59 (3), 345-358, 2015 | 148 | 2015 |
| Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth C Shan, S Elf, Q Ji, HB Kang, L Zhou, T Hitosugi, L Jin, R Lin, L Zhang, ... Molecular cell 55 (4), 552-565, 2014 | 143 | 2014 |
| Targeting glucose metabolism in patients with cancer SE Elf, J Chen Cancer 120 (6), 774-780, 2014 | 133 | 2014 |
| Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms E Chen, RK Schneider, LJ Breyfogle, EA Rosen, L Poveromo, S Elf, A Ko, ... Blood, The Journal of the American Society of Hematology 125 (2), 327-335, 2015 | 125 | 2015 |
| Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation T Hitosugi, L Zhou, J Fan, S Elf, L Zhang, J Xie, Y Wang, TL Gu, ... Nature communications 4 (1), 1790, 2013 | 98 | 2013 |
| Tetrameric acetyl-CoA acetyltransferase 1 is important for tumor growth J Fan, R Lin, S Xia, D Chen, SE Elf, S Liu, Y Pan, H Xu, Z Qian, M Wang, ... Molecular cell 64 (5), 859-874, 2016 | 93 | 2016 |
| Defining the requirements for the pathogenic interaction between mutant calreticulin and MPL in MPN S Elf, NS Abdelfattah, AJ Baral, D Beeson, JF Rivera, A Ko, N Florescu, ... Blood, The Journal of the American Society of Hematology 131 (7), 782-786, 2018 | 89 | 2018 |
| Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect J Fan, HB Kang, C Shan, S Elf, R Lin, J Xie, TL Gu, M Aguiar, S Lonning, ... Journal of Biological Chemistry 289 (38), 26533-26541, 2014 | 89 | 2014 |
| The ability of MLL to bind RUNX1 and methylate H3K4 at PU. 1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations G Huang, X Zhao, L Wang, S Elf, H Xu, X Zhao, G Sashida, Y Zhang, Y Liu, ... Blood, The Journal of the American Society of Hematology 118 (25), 6544-6552, 2011 | 89 | 2011 |
| The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior Y Liu, SE Elf, T Asai, Y Miyata, Y Liu, G Sashida, G Huang, ... Cell cycle 8 (19), 3120-3124, 2009 | 85 | 2009 |
Jing ChenUniversity of Chicago在 medicine.bsd.uchicago.edu 的电子邮件经过验证
