Epigenetic regulator function through mouse gastrulation S Grosswendt, H Kretzmer, ZD Smith, AS Kumar, S Hetzel, L Wittler, ... Nature 584 (7819), 102-108, 2020 | 121 | 2020 |
Hijacking of transcriptional condensates by endogenous retroviruses V Asimi, A Sampath Kumar, H Niskanen, C Riemenschneider, S Hetzel, ... Nature Genetics 54 (8), 1238-1247, 2022 | 50 | 2022 |
Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis MP Rossmann, K Hoi, V Chan, BJ Abraham, S Yang, J Mullahoo, ... Science 372 (6543), 716-721, 2021 | 41 | 2021 |
Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes AR Ringel, Q Szabo, AM Chiariello, K Chudzik, R Schöpflin, P Rothe, ... Cell 185 (20), 3689-3704. e21, 2022 | 38 | 2022 |
Acute lymphoblastic leukemia displays a distinct highly methylated genome S Hetzel, AL Mattei, H Kretzmer, C Qu, X Chen, Y Fan, G Wu, KG Roberts, ... Nature Cancer 3 (6), 768-782, 2022 | 30 | 2022 |
VARSCOT: variant-aware detection and scoring enables sensitive and personalized off-target detection for CRISPR-Cas9 LOW Wilson, S Hetzel, C Pockrandt, K Reinert, DC Bauer BMC Biotechnology 19 (1), 1-7, 2019 | 17 | 2019 |
DNA methylation in mammalian development and disease ZD Smith, S Hetzel, A Meissner Nature Reviews Genetics, 1-24, 2024 | 14 | 2024 |
Nanopype: a modular and scalable nanopore data processing pipeline P Giesselmann, S Hetzel, FJ Müller, A Meissner, H Kretzmer Bioinformatics 35 (22), 4770-4772, 2019 | 12 | 2019 |
Dynamic antagonism between key repressive pathways maintains the placental epigenome R Weigert, S Hetzel, N Bailly, C Haggerty, IA Ilik, PYK Yung, C Navarro, ... Nature Cell Biology 25 (4), 579-591, 2023 | 10 | 2023 |
AML with complex karyotype: extreme genomic complexity revealed by combined long-read sequencing and Hi-C technology MK Klever, E Sträng, S Hetzel, J Jungnitsch, A Dolnik, R Schöpflin, ... Blood Advances 7 (21), 6520-6531, 2023 | 8 | 2023 |
RLM: fast and simplified extraction of read-level methylation metrics from bisulfite sequencing data S Hetzel, P Giesselmann, K Reinert, A Meissner, H Kretzmer Bioinformatics 37 (21), 3934-3935, 2021 | 4 | 2021 |
Extraembryonic gut endoderm cells undergo programmed cell death during development J Batki, S Hetzel, D Schifferl, A Bolondi, M Walther, L Wittler, ... Nature Cell Biology, 1-10, 2024 | 2 | 2024 |
Lambda3: homology search for protein, nucleotide, and bisulfite-converted sequences H Hauswedell, S Hetzel, SG Gottlieb, H Kretzmer, A Meissner, K Reinert Bioinformatics 40 (3), btae097, 2024 | | 2024 |
Investigation of DNA methylation heterogeneity in cancer S Hetzel Freie Universität Berlin, 2023 | | 2023 |