Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage S Stella, P Alcón, G Montoya Nature 546 (7659), 559-563, 2017 | 223 | 2017 |
Conformational activation promotes CRISPR-Cas12a catalysis and resetting of the endonuclease activity S Stella, P Mesa, J Thomsen, B Paul, P Alcón, SB Jensen, B Saligram, ... Cell 175 (7), 1856-1871. e21, 2018 | 209 | 2018 |
FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair P Alcón, S Shakeel, ZA Chen, J Rappsilber, KJ Patel, LA Passmore Nature structural & molecular biology 27 (3), 240-248, 2020 | 104 | 2020 |
Structure of the Fanconi anaemia monoubiquitin ligase complex S Shakeel, E Rajendra, P Alcón, F O’Reilly, DS Chorev, S Maslen, ... Nature 575 (7781), 234-237, 2019 | 102 | 2019 |
Class 2 CRISPR–Cas RNA-guided endonucleases: Swiss Army knives of genome editing S Stella, P Alcon, G Montoya Nature structural & molecular biology 24 (11), 882-892, 2017 | 82 | 2017 |
The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination T Sijacki, P Alcón, ZA Chen, SH McLaughlin, S Shakeel, J Rappsilber, ... Nature structural & molecular biology 29 (9), 881-890, 2022 | 22 | 2022 |
Molecular architecture of the Jumonji C family histone demethylase KDM5B J Dorosz, LH Kristensen, NG Aduri, O Mirza, R Lousen, S Bucciarelli, ... Scientific Reports 9 (1), 4019, 2019 | 22 | 2019 |
PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders JA Manso, T Marcos, V Ruiz-Martín, J Casas, P Alcón, M Sánchez Crespo, ... Cellular and Molecular Life Sciences 79 (2), 131, 2022 | 10 | 2022 |
Assembly of Francisella novicida Cpf1 endonuclease in complex with guide RNA and target DNA P Alcón, G Montoya, S Stella Acta Crystallographica Section F: Structural Biology Communications 73 (7 …, 2017 | 10 | 2017 |
FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination during DNA repair P Alcón, S Shakeel, KJ Patel, LA Passmore BioRxiv, 858225, 2019 | 5 | 2019 |
FANCD2–FANCI surveys DNA and recognizes double-to single-stranded junctions P Alcón, AP Kaczmarczyk, KK Ray, T Liolios, G Guilbaud, T Sijacki, ... Nature 632 (8027), 1165-1173, 2024 | 2 | 2024 |
The histone chaperone SPT2 regulates chromatin structure and function in Metazoa G Saredi, FN Carelli, SGM Rolland, G Furlan, S Piquet, A Appert, ... Nature structural & molecular biology 31 (3), 523-535, 2024 | 2 | 2024 |
Erratum: Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage S Stella, P Alcón, G Montoya Nature 547 (7664), 476-476, 2017 | 2 | 2017 |
FANCD2-FANCI is a sliding DNA clamp that specifically recognizes ss/ds-DNA junctions P Alcon, A Kaczmarczyk, T Sijacki, L Passmore, DS Rueda Biophysical Journal 123 (3), 167a, 2024 | | 2024 |
The histone binding capacity of SPT2 controls chromatin structure and function in Metazoa G Saredi, FN Carelli, SGM Rolland, G Furlan, S Piquet, A Appert, ... Nature Structural & Molecular Biology, 2024 | | 2024 |
The histone chaperone activity of SPT2 controls chromatin structure and function in Metazoa G Saredi, FN Carelli, G Furlan, S Rolland, S Piquet, A Appert, ... bioRxiv, 2023.02. 16.528451, 2023 | | 2023 |
Diffraction images of a crystal of the F-BAR domain of PSTPIP1 (Proline-serine-threonine phosphatase-interacting protein 1) bound to the C-terminal homology (CTH) segment of … JA Manso, P Alcón, Y Bayón, A Alonso, JM Pereda Zenodo, 2020 | | 2020 |
Direct Observation of CRISPR-Cas12 Conformational Sampling by SM FRET and Cryo EM Reveals how Conformational Activation Promotes Catalysis and Resetting of the Endonuclease … S Stella, P Mesa, J Thomsen, B Paul, P Alcon, SB Jensen, ME Moses, ... Biophysical Journal 118 (3), 223a-224a, 2020 | | 2020 |
Conformational activation promotes CRISPR-Cas12a catalysis and resetting of the endonuclease activity N Hatzakis, S Stella, P Mesa, J Thomsen, B Paul, P Alcon, S Jensen, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
CORRECTIONS & AMENDMENTS S Stella, P Alcón, G Montoya NATURE 547, 27, 2017 | | 2017 |