The chemical biology of nitric oxide: implications in cellular signaling DD Thomas, LA Ridnour, JS Isenberg, W Flores-Santana, CH Switzer, ... Free Radical Biology and Medicine 45 (1), 18-31, 2008 | 1033 | 2008 |
Oxidant stress from nitric oxide synthase–3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load E Takimoto, HC Champion, M Li, S Ren, ER Rodriguez, B Tavazzi, ... The Journal of clinical investigation 115 (5), 1221-1231, 2005 | 511 | 2005 |
Positive inotropic and lusitropic effects of HNO/NO− in failing hearts: Independence from β-adrenergic signaling N Paolocci, T Katori, HC Champion, ME St. John, KM Miranda, JM Fukuto, ... Proceedings of the National Academy of Sciences 100 (9), 5537-5542, 2003 | 406 | 2003 |
The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations LA Ridnour, DD Thomas, D Mancardi, MG Espey, KM Miranda, ... Walter de Gruyter 385 (1), 1-10, 2004 | 402 | 2004 |
Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling N Paolocci, WF Saavedra, KM Miranda, C Martignani, T Isoda, JM Hare, ... Proceedings of the National Academy of Sciences 98 (18), 10463-10468, 2001 | 349 | 2001 |
Compartmentalized phosphodiesterase-2 activity blunts β-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway M Mongillo, CG Tocchetti, A Terrin, V Lissandron, YF Cheung, ... Circulation research 98 (2), 226-234, 2006 | 311 | 2006 |
A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system KM Miranda, N Paolocci, T Katori, DD Thomas, E Ford, MD Bartberger, ... Proceedings of the National Academy of Sciences 100 (16), 9196-9201, 2003 | 303 | 2003 |
Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart WF Saavedra, N Paolocci, ME St. John, MW Skaf, GC Stewart, JS Xie, ... Circulation research 90 (3), 297-304, 2002 | 292 | 2002 |
Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy AL Moens, E Takimoto, CG Tocchetti, K Chakir, D Bedja, G Cormaci, ... Circulation 117 (20), 2626-2636, 2008 | 282 | 2008 |
Cardiac phosphodiesterase 5 (cGMP‐specific) modulates β‐adrenergic signaling in vivo and is down‐regulated in heart failure H Senzaki, CJ Smith, GJ Juang, T Isoda, SP Mayer, A Ohler, N Paolocci, ... The FASEB journal 15 (10), 1718-1726, 2001 | 279 | 2001 |
The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO N Paolocci, MI Jackson, BE Lopez, K Miranda, CG Tocchetti, DA Wink, ... Pharmacology & therapeutics 113 (2), 442-458, 2007 | 274 | 2007 |
Nitroxyl Improves Cellular Heart Function by Directly Enhancing Cardiac Sarcoplasmic Reticulum Ca2+ Cycling CG Tocchetti, W Wang, JP Froehlich, S Huke, MA Aon, GM Wilson, ... Circulation research 100 (1), 96-104, 2007 | 244 | 2007 |
Nitroxyl affords thiol-sensitive myocardial protective effects akin to early preconditioning P Pagliaro, D Mancardi, R Rastaldo, C Penna, D Gattullo, KM Miranda, ... Free Radical Biology and Medicine 34 (1), 33-43, 2003 | 233 | 2003 |
The physiological chemistry and biological activity of nitroxyl (HNO): the neglected, misunderstood, and enigmatic nitrogen oxide JM Fukuto, MD Bartberger, AS Dutton, N Paolocci, DA Wink, KN Houk Chemical research in toxicology 18 (5), 790-801, 2005 | 226 | 2005 |
Monoamine oxidase A–mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload N Kaludercic, E Takimoto, T Nagayama, N Feng, EW Lai, D Bedja, ... Circulation research 106 (1), 193-202, 2010 | 224 | 2010 |
Monoamine oxidases as sources of oxidants in the heart N Kaludercic, J Mialet-Perez, N Paolocci, A Parini, F Di Lisa Journal of molecular and cellular cardiology 73, 34-42, 2014 | 220 | 2014 |
Glutathione/thioredoxin systems modulate mitochondrial H2O2 emission: An experimental-computational study MA Aon, BA Stanley, V Sivakumaran, JM Kembro, B O'Rourke, N Paolocci, ... Journal of General Physiology 139 (6), 479-491, 2012 | 206 | 2012 |
Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury N Kaludercic, A Carpi, R Menabò, F Di Lisa, N Paolocci Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (7), 1323-1332, 2011 | 201 | 2011 |
Thioredoxin reductase-2 is essential for keeping low levels of H2O2 emission from isolated heart mitochondria BA Stanley, V Sivakumaran, S Shi, I McDonald, D Lloyd, WH Watson, ... Journal of Biological Chemistry 286 (38), 33669-33677, 2011 | 187 | 2011 |
Cardioprotective effect of beta-3 adrenergic receptor agonism: role of neuronal nitric oxide synthase X Niu, VL Watts, OH Cingolani, V Sivakumaran, JS Leyton-Mange, ... Journal of the American College of Cardiology 59 (22), 1979-1987, 2012 | 185 | 2012 |