TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer RMA Linger, AK Keating, HS Earp, DK Graham Advances in cancer research 100, 35-83, 2008 | 805 | 2008 |
The TAM family: phosphatidylserine-sensing receptor tyrosine kinases gone awry in cancer DK Graham, D DeRyckere, KD Davies, HS Earp Nature Reviews Cancer 14 (12), 769-785, 2014 | 684 | 2014 |
Cloning and mRNA expression analysis of a novel human protooncogene, c-mer. DK Graham, TL Dawson, DL Mullaney, HR Snodgrass, HS Earp Cell growth & differentiation: the molecular biology journal of the American …, 1994 | 415 | 1994 |
A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation S Sather, KD Kenyon, JB Lefkowitz, X Liang, BC Varnum, PM Henson, ... Blood 109 (3), 1026-1033, 2007 | 353 | 2007 |
A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop KE Ware, TK Hinz, E Kleczko, KR Singleton, LA Marek, BA Helfrich, ... Oncogenesis 2 (3), e39-e39, 2013 | 253 | 2013 |
Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer RMA Linger, RA Cohen, CT Cummings, S Sather, J Migdall-Wilson, ... Oncogene 32 (29), 3420-3431, 2013 | 218 | 2013 |
Expression of axl, a transforming receptor tyrosine kinase, in normal and malignant hematopoiesis A Neubauer, A Fiebeler, DK Graham, JP O'Bryan, CA Schmidt, P Barckow, ... | 213 | 1994 |
Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors RMA Linger, AK Keating, HS Earp, DK Graham Expert opinion on therapeutic targets 14 (10), 1073-1090, 2010 | 191 | 2010 |
MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis RS Cook, KM Jacobsen, AM Wofford, D DeRyckere, J Stanford, AL Prieto, ... The Journal of clinical investigation 123 (8), 3231-3242, 2013 | 187 | 2013 |
Cloning and developmental expression analysis of the murine c-mer tyrosine kinase DK Graham, GW Bowman, TL Dawson, WL Stanford, HS Earp, ... Oncogene 10 (12), 2349-2360, 1995 | 178 | 1995 |
Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity AK Keating, GK Kim, AE Jones, AM Donson, K Ware, JM Mulcahy, ... Molecular cancer therapeutics 9 (5), 1298-1307, 2010 | 170 | 2010 |
Outcomes of pregnancies with maternal/paternal exposure in the tofacitinib safety databases for ulcerative colitis U Mahadevan, MC Dubinsky, C Su, N Lawendy, TV Jones, A Marren, ... Inflammatory bowel diseases 24 (12), 2494-2500, 2018 | 161 | 2018 |
UNC2025, a Potent and Orally Bioavailable MER/FLT3 Dual Inhibitor W Zhang, D DeRyckere, D Hunter, J Liu, MA Stashko, KA Minson, ... Journal of medicinal chemistry 57 (16), 7031-7041, 2014 | 152 | 2014 |
MERTK receptor tyrosine kinase is a therapeutic target in melanoma J Schlegel, MJ Sambade, S Sather, SJ Moschos, AC Tan, A Winges, ... The Journal of clinical investigation 123 (5), 2257-2267, 2013 | 152 | 2013 |
Natural killer cell neoplasms X Liang, DK Graham Cancer 112 (7), 1425-1436, 2008 | 137 | 2008 |
Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia DK Graham, DB Salzberg, J Kurtzberg, S Sather, GK Matsushima, ... Clinical cancer research 12 (9), 2662-2669, 2006 | 135 | 2006 |
Molecular pathways: MERTK signaling in cancer CT Cummings, D DeRyckere, HS Earp, DK Graham Clinical Cancer Research 19 (19), 5275-5280, 2013 | 129 | 2013 |
Lymphoblastic leukemia/lymphoma in mice overexpressing the Mer (MerTK) receptor tyrosine kinase AK Keating, DB Salzberg, S Sather, X Liang, S Nickoloff, A Anwar, ... Oncogene 25 (45), 6092-6100, 2006 | 109 | 2006 |
Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia AB Lee-Sherick, KM Eisenman, S Sather, A McGranahan, PM Armistead, ... Oncogene 32 (46), 5359-5368, 2013 | 106 | 2013 |
Discovery of small molecule mer kinase inhibitors for the treatment of pediatric acute lymphoblastic leukemia J Liu, C Yang, C Simpson, D DeRyckere, A Van Deusen, MJ Miley, ... ACS medicinal chemistry letters 3 (2), 129-134, 2012 | 103 | 2012 |