Super-enhancer hypermutation alters oncogene expression in B cell lymphoma E Bal, R Kumar, M Hadigol, AB Holmes, LK Hilton, JW Loh, K Dreval, ... Nature 607 (7920), 808-815, 2022 | 80 | 2022 |
MicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesis A de Conti, JF Ortega, V Tryndyak, K Dreval, FS Moreno, I Rusyn, ... Oncotarget 8 (51), 88517, 2017 | 61 | 2017 |
Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans D Yu, L Wu, P Gill, WH Tolleson, S Chen, J Sun, B Knox, Y Jin, W Xiao, ... Archives of toxicology 92, 845-858, 2018 | 54 | 2018 |
Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma N Thomas, K Dreval, DS Gerhard, LK Hilton, JS Abramson, RF Ambinder, ... Blood 141 (8), 904-916, 2023 | 48 | 2023 |
Quantitative comparison of in vitro genotoxicity between metabolically competent HepaRG cells and HepG2 cells using the high-throughput high-content CometChip assay JE Seo, V Tryndyak, Q Wu, K Dreval, I Pogribny, M Bryant, T Zhou, ... Archives of toxicology 93, 1433-1448, 2019 | 42 | 2019 |
Inhibition of the cell death pathway in nonalcoholic steatohepatitis (NASH)-related hepatocarcinogenesis is associated with histone H4 lysine 16 deacetylation A de Conti, K Dreval, V Tryndyak, OE Orisakwe, SA Ross, FA Beland, ... Molecular Cancer Research 15 (9), 1163-1172, 2017 | 39 | 2017 |
Effect of aflatoxin B1, benzo [a] pyrene, and methapyrilene on transcriptomic and epigenetic alterations in human liver HepaRG cells V Tryndyak, I Kindrat, K Dreval, MI Churchwell, FA Beland, IP Pogribny Food and Chemical Toxicology 121, 214-223, 2018 | 34 | 2018 |
Gene expression and DNA methylation alterations during non-alcoholic steatohepatitis-associated liver carcinogenesis K Dreval, V Tryndyak, A De Conti, FA Beland, IP Pogribny Frontiers in genetics 10, 486, 2019 | 28 | 2019 |
Epigenetically mediated inhibition of S-adenosylhomocysteine hydrolase and the associated dysregulation of 1-carbon metabolism in nonalcoholic steatohepatitis and … IP Pogribny, K Dreval, I Kindrat, S Melnyk, L Jimenez, A de Conti, ... The FASEB Journal 32 (3), 1591, 2018 | 27 | 2018 |
Cellular and molecular effects of prolonged low-level sodium arsenite exposure on human hepatic HepaRG cells K Dreval, V Tryndyak, I Kindrat, NC Twaddle, OE Orisakwe, TK Mudalige, ... Toxicological sciences 162 (2), 676-687, 2018 | 20 | 2018 |
Mir-1247 blocks sox9–mediated regeneration in alcohol-and fibrosis-associated acute kidney injury in mice K Dreval, A de Conti, S Furuya, FA Beland, I Rusyn, IP Pogribny Toxicology 384, 40-49, 2017 | 20 | 2017 |
Нові продуценти целюлозолітичних ензимів серед вищих базидіальних грибів КГ Древаль, МІ Бойко Biotechnology, 87-92, 2011 | 18 | 2011 |
Genetic subdivisions of follicular lymphoma defined by distinct coding and noncoding mutation patterns K Dreval, LK Hilton, M Cruz, H Shaalan, S Ben-Neriah, M Boyle, ... Blood 142 (6), 561-573, 2023 | 17 | 2023 |
Histopathological and molecular signatures of a mouse model of acute-on-chronic alcoholic liver injury demonstrate concordance with human alcoholic hepatitis S Furuya, JA Cichocki, K Konganti, K Dreval, T Uehara, Y Katou, ... Toxicological Sciences 170 (2), 427-437, 2019 | 17 | 2019 |
Poly (ADP-ribose) polymerase 1 (PARP1) promotes oxidative stress–induced association of Cockayne syndrome group B protein with chromatin EL Boetefuer, RJ Lake, K Dreval, HY Fan Journal of Biological Chemistry 293 (46), 17863-17874, 2018 | 17 | 2018 |
HDAC1 negatively regulates selective mitotic chromatin binding of the Notch effector RBPJ in a KDM5A-dependent manner K Dreval, RJ Lake, HY Fan Nucleic acids research 47 (9), 4521-4538, 2019 | 15 | 2019 |
Relapse timing is associated with distinct evolutionary dynamics in diffuse large B-cell lymphoma LK Hilton, HS Ngu, B Collinge, K Dreval, S Ben-Neriah, CK Rushton, ... Journal of Clinical Oncology 41 (25), 4164-4177, 2023 | 12 | 2023 |
Editor’s highlight: organ-specific epigenetic changes induced by the nongenotoxic liver carcinogen methapyrilene in fischer 344 rats S Shpyleva, K Dreval, A de Conti, I Kindrat, S Melnyk, J Yan, T Chen, ... Toxicological Sciences 156 (1), 190-198, 2017 | 10 | 2017 |
Shared and distinct genetic features in human and canine B-cell lymphomas KM Coyle, T Hillman, M Cheung, BM Grande, KR Bushell, SE Arthur, ... Blood Advances 6 (11), 3404-3409, 2022 | 7 | 2022 |
Effect of methapyrilene hydrochloride on hepatic intracellular iron metabolism in vivo and in vitro I Kindrat, K Dreval, S Shpyleva, V Tryndyak, A de Conti, TK Mudalige, ... Toxicology Letters 281, 65-73, 2017 | 7 | 2017 |