| The ATLAS simulation infrastructure ATLAS Collaboration atlas. secretariat@ cern. ch, G Aad, B Abbott, ... The European Physical Journal C 70 (3), 823-874, 2010 | 9022 | 2010 |
| Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ... Nature genetics 41 (10), 1088-1093, 2009 | 3322 | 2009 |
| TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis J Sreedharan, IP Blair, VB Tripathi, X Hu, C Vance, B Rogelj, S Ackerley, ... Science 319 (5870), 1668-1672, 2008 | 3022 | 2008 |
| Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6 C Vance, B Rogelj, T Hortobágyi, KJ De Vos, AL Nishimura, J Sreedharan, ... Science 323 (5918), 1208-1211, 2009 | 3003 | 2009 |
| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2267 | 2019 |
| Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ... Nature genetics 43 (5), 429-435, 2011 | 2193 | 2011 |
| Amyotrophic lateral sclerosis RH Brown, A Al-Chalabi New England Journal of Medicine 377 (2), 162-172, 2017 | 1963 | 2017 |
| Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS HJ Kim, NC Kim, YD Wang, EA Scarborough, J Moore, Z Diaz, ... Nature 495 (7442), 467-473, 2013 | 1548 | 2013 |
| Characterizing the RNA targets and position-dependent splicing regulation by TDP-43 JR Tollervey, T Curk, B Rogelj, M Briese, M Cereda, M Kayikci, J König, ... Nature neuroscience 14 (4), 452-458, 2011 | 1222 | 2011 |
| VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death D Lambrechts, E Storkebaum, M Morimoto, J Del-Favero, F Desmet, ... Nature genetics 34 (4), 383-394, 2003 | 1119 | 2003 |
| Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways ET Cirulli, BN Lasseigne, S Petrovski, PC Sapp, PA Dion, CS Leblond, ... Science 347 (6229), 1436-1441, 2015 | 1003 | 2015 |
| Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 920 | 2017 |
| Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study MR Turner, A Cagnin, FE Turkheimer, CCJ Miller, CE Shaw, DJ Brooks, ... Neurobiology of disease 15 (3), 601-609, 2004 | 836 | 2004 |
| Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations NH Alami, RB Smith, MA Carrasco, LA Williams, CS Winborn, SSW Han, ... Neuron 81 (3), 536-543, 2014 | 700 | 2014 |
| Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ... Nature genetics 48 (9), 1043-1048, 2016 | 601 | 2016 |
| ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43 R Stoica, KJ De Vos, S Paillusson, S Mueller, RM Sancho, KF Lau, ... Nature communications 5 (1), 3996, 2014 | 600 | 2014 |
| Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1267-1288, 2018 | 597 | 2018 |
| Proteome-based plasma biomarkers for Alzheimer's disease A Hye, S Lynham, M Thambisetty, M Causevic, J Campbell, HL Byers, ... Brain 129 (11), 3042-3050, 2006 | 585 | 2006 |
| Senataxin, the ortholog of a yeast RNA helicase, is mutant in ataxia-ocular apraxia 2 MC Moreira, S Klur, M Watanabe, AH Németh, IL Ber, JC Moniz, ... Nature genetics 36 (3), 225-227, 2004 | 577 | 2004 |
| Gain of toxicity from ALS/FTD-linked repeat expansions in C9ORF72 is alleviated by antisense oligonucleotides targeting GGGGCC-containing RNAs J Jiang, Q Zhu, TF Gendron, S Saberi, M McAlonis-Downes, A Seelman, ... Neuron 90 (3), 535-550, 2016 | 573 | 2016 |
