| Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA … WM Eldehna, H Almahli, GH Al-Ansary, HA Ghabbour, MH Aly, OE Ismael, ... Journal of Enzyme Inhibition and Medicinal Chemistry 32 (1), 600-613, 2017 | 78 | 2017 |
| Pyridine-ureas as potential anticancer agents: synthesis and in vitro biological evaluation M El-Naggar, H Almahli, HS Ibrahim, WM Eldehna, HA Abdel-Aziz Molecules 23 (6), 1459, 2018 | 73 | 2018 |
| Development of novel synthesized phthalazinone-based PARP-1 inhibitors with apoptosis inducing mechanism in lung cancer H Almahli, E Hadchity, MY Jaballah, R Daher, HA Ghabbour, MM Kabil, ... Bioorganic Chemistry 77, 443-456, 2018 | 69 | 2018 |
| Novel [(N-alkyl-3-indolylmethylene) hydrazono] oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in … T Al-Warhi, MF Abo-Ashour, H Almahli, OJ Alotaibi, MM Al-Sanea, ... Journal of enzyme inhibition and medicinal chemistry 35 (1), 1300-1309, 2020 | 54 | 2020 |
| Novel Thiazolidinone/Thiazolo[3,2-a]Benzimidazolone-Isatin Conjugates as Apoptotic Anti-proliferative Agents Towards Breast Cancer: One-Pot Synthesis and In … M El-Naggar, WM Eldehna, H Almahli, A Elgez, M Fares, MM Elaasser, ... Molecules 23 (6), 1420, 2018 | 53 | 2018 |
| Identification of 3-(piperazinylmethyl)benzofuran derivatives as novel type II CDK2 inhibitors: design, synthesis, biological evaluation, and in silico insights WM Eldehna, RM Maklad, H Almahli, T Al-Warhi, EB Elkaeed, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1227-1240, 2022 | 22 | 2022 |
| Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors MA Shaldam, H Almahli, A Angeli, RM Badi, EF Khaleel, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2203389, 2023 | 21 | 2023 |
| 1, 5-diaryl-1, 2, 4-triazole ureas as new SLC-0111 analogues endowed with dual carbonic anhydrase and VEGFR-2 inhibitory activities AE Elsawi, MM Elbadawi, A Nocentini, H Almahli, S Giovannuzzi, ... Journal of Medicinal Chemistry 66 (15), 10558-10578, 2023 | 21 | 2023 |
| Synthesis, in vitro biological evaluation and in silico studies of certain arylnicotinic acids conjugated with aryl (thio) semicarbazides as a novel class of anti-leishmanial … WM Eldehna, H Almahli, TM Ibrahim, M Fares, T Al-Warhi, FM Boeckler, ... European Journal of Medicinal Chemistry 179, 335-346, 2019 | 20 | 2019 |
| Novel 3-(6-methylpyridin-2-yl) coumarin-based chalcones as selective inhibitors of cancer-related carbonic anhydrases IX and XII endowed with anti-proliferative activity HO Tawfik, MA Shaldam, A Nocentini, R Salem, H Almahli, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1043-1052, 2022 | 18 | 2022 |
| Synthesis, biological evaluation and molecular docking of certain sulfones as potential nonazole antifungal agents M Fares, MA Said, MA Alsherbiny, RA Eladwy, H Almahli, MM Abdel-Aziz, ... Molecules 21 (1), 114, 2016 | 17 | 2016 |
| Development of Novel Isatin-Tethered Quinolines as Anti-Tubercular Agents against Multi and Extensively Drug-Resistant Mycobacterium tuberculosis MA Abdelrahman, H Almahli, T Al-Warhi, TA Majrashi, MM Abdel-Aziz, ... Molecules 27 (24), 8807, 2022 | 16 | 2022 |
| Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation MA Abdelrahman, WM Eldehna, A Nocentini, HS Ibrahim, H Almahli, ... Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 298-305, 2020 | 16 | 2020 |
| The asymmetric Michael-type alkylation of chiral β-enamino esters: critical role of a benzyl ester group in the racemization of adducts M Pizzonero, F Hendra, S Delarue-Cochin, MET Huu-Dau, F Dumas, ... Tetrahedron: Asymmetry 16 (23), 3853-3857, 2005 | 15 | 2005 |
| Asymmetric Michael reaction between a chiral α, β-dimethyl-β-enamino ester and α-substituted acrylates F Hendra, M Nour, I Baglin, G Morgant, C Cavé Tetrahedron: Asymmetry 15 (6), 1027-1032, 2004 | 14 | 2004 |
| 1-Benzyl-5-bromo-3-hydrazonoindolin-2-ones as novel anticancer agents: Synthesis, biological evaluation and molecular modeling insights T Al-Warhi, H Almahli, RM Maklad, ZM Elsayed, MA El Hassab, ... Molecules 28 (7), 3203, 2023 | 13 | 2023 |
| Synergistic Effect of Sophora japonica and Glycyrrhiza glabra Flavonoid-Rich Fractions on Wound Healing: In Vivo and Molecular Docking Studies SH Aly, AM Elissawy, AMA Mahmoud, FS El-Tokhy, SSA Mageed, ... Molecules 28 (7), 2994, 2023 | 13 | 2023 |
| Discovery of indolinone-bearing benzenesulfonamides as new dual carbonic anhydrase and VEGFR-2 inhibitors possessing anticancer and pro-apoptotic properties S Saied, M Shaldam, MM Elbadawi, S Giovannuzzi, A Nocentini, ... European Journal of Medicinal Chemistry 259, 115707, 2023 | 12 | 2023 |
| Unexpected synthesis, single-crystal x-ray structure, anticancer activity, and molecular docking studies of certain 2–((imidazole/benzimidazol–2–yl) thio)–1–arylethanones T Al-Warhi, MA Said, MA El Hassab, N Aljaeed, HA Ghabour, H Almahli, ... Crystals 10 (6), 446, 2020 | 12 | 2020 |
| GC/MS Profiling of the Essential Oil and Lipophilic Extract of Moricandia sinaica Boiss. and Evaluation of Their Cytotoxic and Antioxidant Activities SH Aly, NH Kandil, RM Hemdan, SS Kotb, SS Zaki, OM Abdelaziz, ... Molecules 28 (5), 2193, 2023 | 10 | 2023 |
