Novel “anti-reverse” cap analogs with superior translational properties J Jemielity, T Fowler, J Zuberek, J Stepinski, M Lewdorowicz, ... Rna 9 (9), 1108-1122, 2003 | 446 | 2003 |
Phosphorothioate cap analogs stabilize mRNA and increase translational efficiency in mammalian cells E Grudzien-Nogalska, J Jemielity, J Kowalska, E Darzynkiewicz, ... Rna 13 (10), 1745-1755, 2007 | 284 | 2007 |
Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo AN Kuhn, M Diken, S Kreiter, A Selmi, J Kowalska, J Jemielity, ... Gene therapy 17 (8), 961-971, 2010 | 262 | 2010 |
The strategies to support the COVID-19 vaccination with evidence-based communication and tackling misinformation P Rzymski, L Borkowski, M Drąg, R Flisiak, J Jemielity, J Krajewski, ... Vaccines 9 (2), 109, 2021 | 178 | 2021 |
Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS J Kowalska, M Lewdorowicz, J Zuberek, E Grudzien-Nogalska, ... Rna 14 (6), 1119-1131, 2008 | 153 | 2008 |
mRNA decapping is promoted by an RNA-binding channel in Dcp2 MV Deshmukh, BN Jones, DU Quang-Dang, J Flinders, SN Floor, C Kim, ... Molecular cell 29 (3), 324-336, 2008 | 127 | 2008 |
Differential inhibition of mRNA degradation pathways by novel cap analogs E Grudzien, M Kalek, J Jemielity, E Darzynkiewicz, RE Rhoads Journal of Biological Chemistry 281 (4), 1857-1867, 2006 | 115 | 2006 |
Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression A Zdanowicz, R Thermann, J Kowalska, J Jemielity, K Duncan, T Preiss, ... Molecular cell 35 (6), 881-888, 2009 | 109 | 2009 |
Synthesis of anti‐reverse cap analogs (ARCAs) and their applications in mRNA translation and stability E Grudzien‐Nogalska, J Stepinski, J Jemielity, J Zuberek, R Stolarski, ... Methods in enzymology 431, 203-227, 2007 | 107 | 2007 |
The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5′ cap modulates protein expression in living cells PJ Sikorski, M Warminski, D Kubacka, T Ratajczak, D Nowis, J Kowalska, ... Nucleic Acids Research 48 (4), 1607-1626, 2020 | 99 | 2020 |
Weak binding affinity of human 4EHP for mRNA cap analogs J Zuberek, D Kubacka, A Jablonowska, J Jemielity, J Stepinski, ... Rna 13 (5), 691-697, 2007 | 97 | 2007 |
Vaccine composition comprising 5′-cap modified RNA U Sahin, A Kuhn, E Darzynkiewicz, J Jemielity, J Kowalska US Patent 9,295,717, 2016 | 95 | 2016 |
Synthetic mRNA cap analogs with a modified triphosphate bridge–synthesis, applications and prospects J Jemielity, J Kowalska, AM Rydzik, E Darzynkiewicz New Journal of Chemistry 34 (5), 829-844, 2010 | 94 | 2010 |
Influence of Electric Charge Variation at Residues 209 and 159 on the Interaction of eIF4E with the mRNA 5 ‘Terminus J Zuberek, J Jemielity, A Jablonowska, J Stepinski, M Dadlez, R Stolarski, ... Biochemistry 43 (18), 5370-5379, 2004 | 85 | 2004 |
5′-phosphorothiolate dinucleotide cap analogues: Reagents for messenger RNA modification and potent small-molecular inhibitors of decapping enzymes BA Wojtczak, PJ Sikorski, K Fac-Dabrowska, A Nowicka, M Warminski, ... Journal of the American Chemical Society 140 (18), 5987-5999, 2018 | 80 | 2018 |
Cap analogs modified with 1, 2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential M Strenkowska, R Grzela, M Majewski, K Wnek, J Kowalska, ... Nucleic acids research 44 (20), 9578-9590, 2016 | 79 | 2016 |
Potential therapeutic applications of RNA cap analogs M Ziemniak, M Strenkowska, J Kowalska, J Jemielity Future medicinal chemistry 5 (10), 1141-1172, 2013 | 78 | 2013 |
Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes J Kowalska, AW del Nogal, ZM Darzynkiewicz, J Buck, C Nicola, AN Kuhn, ... Nucleic acids research 42, 10245-10264, 2014 | 74 | 2014 |
Synthetic mRNAs with superior translation and stability properties E Grudzien-Nogalska, J Kowalska, W Su, AN Kuhn, SV Slepenkov, ... Synthetic Messenger RNA and Cell Metabolism Modulation: Methods and …, 2013 | 74 | 2013 |
Synthesis and use of anti-reverse phosphorothioate analogs of the messenger RNA cap J Jemielity, EM Grudzien-Nogalska, J Kowalska, E Darzynkiewicz, ... US Patent 8,153,773, 2012 | 71 | 2012 |