| Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons JW Um, HB Nygaard, JK Heiss, MA Kostylev, M Stagi, A Vortmeyer, ... Nature neuroscience 15 (9), 1227-1235, 2012 | 752 | 2012 |
| Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein JW Um, AC Kaufman, M Kostylev, JK Heiss, M Stagi, H Takahashi, ... Neuron 79 (5), 887-902, 2013 | 637 | 2013 |
| F yn inhibition rescues established memory and synapse loss in A lzheimer mice AC Kaufman, SV Salazar, LT Haas, J Yang, MA Kostylev, AT Jeng, ... Annals of neurology 77 (6), 953-971, 2015 | 329 | 2015 |
| Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer’s disease LT Haas, SV Salazar, MA Kostylev, JW Um, AC Kaufman, SM Strittmatter Brain 139 (2), 526-546, 2016 | 138 | 2016 |
| Prion-protein-interacting amyloid-β oligomers of high molecular weight are tightly correlated with memory impairment in multiple Alzheimer mouse models MA Kostylev, AC Kaufman, HB Nygaard, P Patel, LT Haas, EC Gunther, ... Journal of Biological Chemistry 290 (28), 17415-17438, 2015 | 135 | 2015 |
| Liquid and hydrogel phases of PrPC linked to conformation shifts and triggered by Alzheimer’s amyloid-β oligomers MA Kostylev, MD Tuttle, S Lee, LE Klein, H Takahashi, TO Cox, ... Molecular cell 72 (3), 426-443. e12, 2018 | 102 | 2018 |
| Therapeutic molecules and endogenous ligands regulate the interaction between brain cellular prion protein (PrPC) and metabotropic glutamate receptor 5 (mGluR5) LT Haas, MA Kostylev, SM Strittmatter Journal of Biological Chemistry 289 (41), 28460-28477, 2014 | 91 | 2014 |
| Brivaracetam, but not ethosuximide, reverses memory impairments in an Alzheimer’s disease mouse model HB Nygaard, AC Kaufman, T Sekine-Konno, LL Huh, H Going, ... Alzheimer's research & therapy 7, 1-12, 2015 | 90 | 2015 |
| Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network H Takahashi, ZA Klein, SM Bhagat, AC Kaufman, MA Kostylev, T Ikezu, ... Acta neuropathologica 133, 785-807, 2017 | 83 | 2017 |
| Systematic and standardized comparison of reported amyloid-β receptors for sufficiency, affinity, and Alzheimer's disease relevance LM Smith, MA Kostylev, S Lee, SM Strittmatter Journal of Biological Chemistry 294 (15), 6042-6053, 2019 | 65 | 2019 |
| Rescue of transgenic Alzheimer’s pathophysiology by polymeric cellular prion protein antagonists EC Gunther, LM Smith, MA Kostylev, TO Cox, AC Kaufman, S Lee, ... Cell reports 26 (1), 145-158. e8, 2019 | 43 | 2019 |
| Early activation of experience-independent dendritic spine turnover in a mouse model of Alzheimer's disease JK Heiss, J Barrett, Z Yu, LT Haas, MA Kostylev, SM Strittmatter Cerebral cortex 27 (7), 3660-3674, 2017 | 26 | 2017 |
| Cellular Prion Protein as a Receptor for Toxic Beta Amyloid Oligomers: Understanding The Molecular Mechanism of Alzheimer's Disease MA Kostylev Yale University, 2015 | 1 | 2015 |
| A Synaptotoxic Pathway from Aβ oligomer to Prion Protein to mGluR5 to F kinase in Alzheimer's Disease S Strittmatter, M Kostylev, AC Kaufman, L Haas, JK Heiss, EC Gunther, ... Neurobiology of Aging, S21, 2014 | 1 | 2014 |
| Biological sample capture with multiplex analysis M Kostylev, E Gunther US Patent App. 17/732,932, 2022 | | 2022 |
| Intragel well sample loading system E Gunther, M Kostylev, S Strittmatter US Patent App. 17/634,657, 2022 | | 2022 |
| Protein Capture Membrane and Method of Use Thereof E Gunther, M Kostylev, S Strittmatter US Patent App. 17/053,023, 2021 | | 2021 |
| F5‐02‐02: Aß oligomer induced signal transduction at the post‐synaptic density A Kaufman, M Kostylev, L Haas, S Salazar, S Strittmatter Alzheimer's & Dementia 11 (7S_Part_6), P305-P305, 2015 | | 2015 |
| Supplemental Information Alzheimer Amyloid-ß Oligomer Bound to Post-Synaptic Prion Protein Activates Fyn to Impair Neurons JW Um, HB Nygaard, JK Heiss, MA Kostylev, M Stagi, A Vortmeyer, ... | | |
