Synthetic lethality of PARP inhibitors in combination with MYC blockade is independent of BRCA status in triple-negative breast cancer JPW Carey, C Karakas, T Bui, X Chen, S Vijayaraghavan, Y Zhao, J Wang, ... Cancer research 78 (3), 742-757, 2018 | 118 | 2018 |
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer NM Kettner, S Vijayaraghavan, MG Durak, T Bui, M Kohansal, MJ Ha, ... Clinical Cancer Research 25 (13), 3996-4013, 2019 | 101 | 2019 |
Cyclin E Overexpression Sensitizes Triple-Negative Breast Cancer to Wee1 Kinase Inhibition X Chen, KH Low, A Alexander, Y Jiang, C Karakas, KR Hess, JPW Carey, ... Clinical Cancer Research 24 (24), 6594-6610, 2018 | 95 | 2018 |
AXL Inhibition Suppresses the DNA Damage Response and Sensitizes Cells to PARP Inhibition in Multiple Cancers K Balaji, S Vijayaraghavan, L Diao, P Tong, Y Fan, JPW Carey, TN Bui, ... Molecular Cancer Research 15 (1), 45-58, 2017 | 89 | 2017 |
Inhibitor of differentiation 4 (Id4) is a potential tumor suppressor in prostate cancer JPW Carey, AJ Asirvatham, O Galm, TA Ghogomu, J Chaudhary BMC cancer 9 (1), 173, 2009 | 82 | 2009 |
ID1‐, ID2‐, and ID3‐regulated gene expression in E2A positive or negative prostate cancer cells AJ Asirvatham, JPW Carey, J Chaudhary The Prostate 67 (13), 1411-1420, 2007 | 82 | 2007 |
Inhibitor of differentiation 4 (ID4): From development to cancer D Patel, DJ Morton, J Carey, MC Havrda, J Chaudhary Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1855 (1), 92-103, 2015 | 78 | 2015 |
Low-Molecular-Weight Cyclin E in Human Cancer: Cellular Consequences and Opportunities for Targeted Therapies JA Caruso, MT Duong, JPW Carey, KK Hunt, K Keyomarsi Cancer research 78 (19), 5481-5491, 2018 | 68 | 2018 |
Cyclin E overexpression as a biomarker for combination treatment strategies in inflammatory breast cancer A Alexander, C Karakas, X Chen, JPW Carey, M Yi, M Bondy, ... Oncotarget 8 (9), 14897, 2017 | 43 | 2017 |
Epigenetic inactivation of inhibitor of differentiation 4 (Id4) correlates with prostate cancer P Sharma, S Chinaranagari, D Patel, J Carey, J Chaudhary Cancer medicine 1 (2), 176-186, 2012 | 39 | 2012 |
Id4 promotes senescence and sensitivity to doxorubicin-induced apoptosis in DU145 prostate cancer cells JP Carey, AE Knowell, S Chinaranagari, J Chaudhary Anticancer research 33 (10), 4271-4278, 2013 | 25 | 2013 |
Targeting replicative stress and DNA repair by combining PARP and Wee1 kinase inhibitors is synergistic in triple negative breast cancers with cyclin E or BRCA1 alteration X Chen, D Yang, JPW Carey, C Karakas, C Albarracin, AA Sahin, BK Arun, ... Cancers 13 (7), 1656, 2021 | 21 | 2021 |
PKCiota promotes ovarian tumor progression through deregulation of cyclin E A Nanos-Webb, T Bui, C Karakas, D Zhang, JPW Carey, GB Mills, ... Oncogene 35 (19), 2428-2440, 2016 | 20 | 2016 |
Characterizing acquired resistance to palbociclib in breast cancer S Vijayaraghavan, I Doostan, JPW Carey, K Keyomarsi Cancer Research 77 (13 Supplement), 2060-2060, 2017 | 5 | 2017 |
Leveraging MYC as a therapeutic treatment option for TNBC JPW Carey, K Keyomarsi Oncoscience 5 (5-6), 137, 2018 | 2 | 2018 |
Abstract B27: CDK inhibition impairs homologous recombination and induces PARP inhibitor sensitivity via loss of c-myc expression in TNBC JP Carey, K Keyomarsi Molecular Cancer Research 13 (10 Supplement), B27-B27, 2015 | 1 | 2015 |
Combined inhibition of STAT-3 & DNA repair in palbociclib resistant breast cancer NM Kettner, S Vijayaraghavan, MG Durak, T Bui, M Kohansal, MJ Ha, ... Cancer Research 79 (13 Supplement), 323-323, 2019 | | 2019 |
Abstract A15: Downregulation of c-myc is synthetic lethal with PARP inhibitors in high MYC cancers independent of BRCA status JPW Carey, S Vjayaraghavan, K Hunt, K Keyomarsi Molecular Cancer Therapeutics 16 (10 Supplement), A15-A15, 2017 | | 2017 |
CDK inhibition impairs homologous recombination and induces PARP inhibitor sensitivity via loss of c-myc expression in TNBC JP Carey, K Keyomarsi MOLECULAR CANCER RESEARCH 14, 2016 | | 2016 |
Targeting the Cell Cycle in Breast Cancer JP Carey, K Keyomarsi Breast Diseases 27 (4), 256-260, 2016 | | 2016 |