| Functional Classification of BRCA2 DNA Variants by Splicing Assays in a Large Minigene with 9 Exons. A Acedo, C Hernández Moro, Á Curiel-García, EA Velasco Human Mutation, 2014 | 67 | 2014 |
| Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling B Oldrini, Á Curiel-García, C Marques, V Matia, Ö Uluçkan, ... Nature communications 9 (1), 1466, 2018 | 65 | 2018 |
| Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer UN Wasko, J Jiang, TC Dalton, A Curiel-Garcia, AC Edwards, Y Wang, ... Nature, 1-3, 2024 | 35 | 2024 |
| EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer B Oldrini, WY Hsieh, H Erdjument-Bromage, P Codega, MS Carro, ... Nature communications 8 (1), 2035, 2017 | 29 | 2017 |
| Pancreatic ductal adenocarcinoma comprises coexisting regulatory states with both common and distinct dependencies P Laise, M Turunen, HC Maurer, AG Curiel, E Elyada, B Schmierer, ... Biorxiv, preprint, 2020 | 16 | 2020 |
| Dianhydrogalactitol overcomes multiple temozolomide resistance mechanisms in glioblastoma M Jiménez-Alcázar, Á Curiel-García, P Nogales, J Perales-Patón, ... Molecular cancer therapeutics 20 (6), 1029-1038, 2021 | 10 | 2021 |
| Tumor explants elucidate a Cascade of Paracrine SHH, WNT, and VEGF signals driving pancreatic Cancer Angiosuppression MC Hasselluhn, AR Decker-Farrell, L Vlahos, DH Thomas, ... Cancer discovery 14 (2), 348-361, 2024 | 8 | 2024 |
| Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma UN Wasko, J Jiang, A Curiel-Garcia, Y Wang, B Lee, M Orlen, ... bioRxiv, 2023 | 7 | 2023 |
| Pharmacological targeting of the receptor ALK inhibits tumorigenicity and overcomes chemoresistance in pancreatic ductal adenocarcinoma B Parejo-Alonso, A Royo-García, P Espiau-Romera, S Courtois, ... Biomedicine & Pharmacotherapy 158, 114162, 2023 | 6 | 2023 |
| Generation of orthotopic patient-derived xenograft models for pancreatic cancer using tumor slices A Curiel-Garcia, AR Decker-Farrell, SA Sastra, KP Olive STAR protocols 3 (4), 101899, 2022 | 4 | 2022 |
| Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer HC Maurer, A Curiel-Garcia, S Holmstrom, P Laise, CF Palermo, ... bioRxiv, 2023 | 3 | 2023 |
| Developmental and MAPK-responsive transcription factors drive distinct malignant subtypes and genetic dependencies in pancreatic cancer P Laise, M Turunen, AC Garcia, L Tomassoni, HC Maurer, E Elyada, ... bioRxiv, 2020.10. 27.357269, 2020 | 3 | 2020 |
| DRES-12. FUNCTIONAL GENETIC APPROACHES TO OVERCOME TEMOZOLOMIDE RESISTANCE IN GLIOBLASTOMA P Nogales-Gomez, J Perales-Patón, A Jimenez-Schuhmacher, ... Neuro-oncology 20 (Suppl 6), vi78, 2018 | 1 | 2018 |
| Abstract B014: Leveraging T cell anti-tumor immunity to enhance the efficacy of Ras inhibition in pancreatic cancer T Dalton, U Wasko, A Curiel-Garcia, S Sastra, C Palermo, M Hasselluhn, ... Cancer Immunology Research 12 (10_Supplement), B014-B014, 2024 | | 2024 |
| Abstract A045: Disrupting local immunosuppression through combination myCAF/myeloid targeting in pancreatic cancer MC Hasselluhn, L Vlahos, D Thomas, QT Waterbury, AC Garcia, ... Cancer Research 84 (17_Supplement_2), A045-A045, 2024 | | 2024 |
| Disrupting local immunosuppression by combined myCAF/myeloid targeting in pancreatic cancer MC Hasselluhn, D Thomas, L Vlahos, A Curiel-Garcia, AR Decker-Farrell, ... Cancer Research 84 (6_Supplement), 1596-1596, 2024 | | 2024 |
| Adaptive heterogeneity enables the survival of residual malignant PDAC cells in response to RAS-GTP inhibition L Tomassoni, UN Wasko, AC Garcia, TC Dalton, P Laise, SA Sastra, ... Cancer Research 84 (6_Supplement), 3874-3874, 2024 | | 2024 |
| RAS-GTP inhibition modulates Hedgehog signaling, suppressing myCAFs and promoting iCAFs in pancreatic ductal adenocarcinoma M Hasselluhn, L Tomassoni, U Wasko, A Curiel-Garcia, T Dalton, ... Cancer Research 84 (6_Supplement), 1578-1578, 2024 | | 2024 |
| RNA-based precision medicine predicts sensitivity to selinexor in select pancreatic ductal adenocarcinoma patients A Curiel-Garcia, L Tomassoni, TC Dalton, AR Decker-Farrell, CF Palermo, ... Cancer Research 84 (6_Supplement), 934-934, 2024 | | 2024 |
| Resistance to RAS-GTP inhibition in models of pancreatic ductal adenocarcinoma arises downstream of RAS effectors UN Wasko, J Jiang, TC Dalton, A Curiel-Garcia, AC Edwards, Y Wang, ... Cancer Research 84 (6_Supplement), 1927-1927, 2024 | | 2024 |
