Therapeutic strategies underpinning the development of novel techniques for the treatment of HIV infection JJ Tan, XJ Cong, LM Hu, CX Wang, L Jia, XJ Liang Drug discovery today 15 (5-6), 186-197, 2010 | 101 | 2010 |
Common structural traits across pathogenic mutants of the human prion protein and their implications for familial prion diseases G Rossetti, X Cong, R Caliandro, G Legname, P Carloni Journal of molecular biology 411 (3), 700-712, 2011 | 75 | 2011 |
Structure of the vasopressin hormone–V2 receptor–β-arrestin1 ternary complex J Bous, A Fouillen, H Orcel, S Trapani, X Cong, S Fontanel, J Saint-Paul, ... Science Advances 8 (35), eabo7761, 2022 | 46 | 2022 |
Molecular insights into the biased signaling mechanism of the μ-opioid receptor X Cong, D Maurel, H Déméné, I Vasiliauskaité-Brooks, J Hagelberger, ... Molecular Cell 81 (20), 4165-4175. e6, 2021 | 45 | 2021 |
Developing predictive rules for coordination geometry from visible circular dichroism of copper (II) and nickel (II) ions in histidine and amide main‐chain complexes HF Stanyon, X Cong, Y Chen, N Shahidullah, G Rossetti, J Dreyer, ... The FEBS Journal 281 (17), 3945-3954, 2014 | 43 | 2014 |
Class A GPCRs: Structure, function, modeling and structure-based ligand design X Cong, J Topin, J Golebiowski Current pharmaceutical design 23 (29), 4390-4409, 2017 | 34 | 2017 |
Zebrafish olfactory receptors ORAs differentially detect bile acids and bile salts X Cong, Q Zheng, W Ren, JB Chéron, S Fiorucci, T Wen, C Zhang, H Yu, ... Journal of Biological Chemistry 294 (17), 6762-6771, 2019 | 32 | 2019 |
Liposomal FRET Assay Identifies Potent Drug‐Like Inhibitors of the Ceramide Transport Protein (CERT) D Samaha, HH Hamdo, X Cong, F Schumacher, S Banhart, Ö Aglar, ... Chemistry–A European Journal 26 (70), 16616-16621, 2020 | 31 | 2020 |
Large-scale G protein-coupled olfactory receptor–ligand pairing X Cong, W Ren, J Pacalon, R Xu, L Xu, X Li, CA de March, H Matsunami, ... ACS Central Science 8 (3), 379-387, 2022 | 27 | 2022 |
Structural determinants for the binding of morphinan agonists to the μ-opioid receptor X Cong, P Campomanes, A Kless, I Schapitz, M Wagener, T Koch, ... PLoS One 10 (8), e0135998, 2015 | 27 | 2015 |
Discovery and mechanism of action of small molecule inhibitors of ceramidases RD Healey, EM Saied, X Cong, G Karsai, L Gabellier, J Saint‐Paul, ... Angewandte Chemie International Edition 61 (2), e202109967, 2022 | 24 | 2022 |
Structural heterogeneity of the μ-opioid receptor’s conformational ensemble in the apo state DM Sena Jr, X Cong, A Giorgetti, A Kless, P Carloni Scientific reports 7 (1), 45761, 2017 | 24 | 2017 |
Role of prion disease-linked mutations in the intrinsically disordered N-terminal domain of the prion protein X Cong, N Casiraghi, G Rossetti, S Mohanty, G Giachin, G Legname, ... Journal of chemical theory and computation 9 (11), 5158-5167, 2013 | 21 | 2013 |
Study on the inhibitory mechanism and binding mode of the hydroxycoumarin compound NSC158393 to HIV‐1 integrase by molecular modeling M Liu, XJ Cong, P Li, JJ Tan, WZ Chen, CX Wang Biopolymers: Original Research on Biomolecules 91 (9), 700-709, 2009 | 21 | 2009 |
Three-dimensional QSAR analyses of 1, 3, 4-trisubstituted pyrrolidine-based CCR5 receptor inhibitors Y Zhuo, R Kong, X Cong, C Wang European journal of medicinal chemistry 43 (12), 2724-2734, 2008 | 20 | 2008 |
Activation dynamics of the neurotensin G protein-coupled receptor 1 X Cong, S Fiorucci, J Golebiowski Journal of chemical theory and computation 14 (8), 4467-4473, 2018 | 18 | 2018 |
Allosteric Na+-binding site modulates CXCR4 activation X Cong, J Golebiowski Physical Chemistry Chemical Physics 20 (38), 24915-24920, 2018 | 17 | 2018 |
Novel angiogenin mutants with increased cytotoxicity enhance the depletion of pro-inflammatory macrophages and leukemia cells ex vivo C Cremer, H Braun, R Mladenov, L Schenke, X Cong, E Jost, ... Cancer Immunology, Immunotherapy 64, 1575-1586, 2015 | 15 | 2015 |
Dominant-negative effects in prion diseases: insights from molecular dynamics simulations on mouse prion protein chimeras X Cong, S Bongarzone, G Giachin, G Rossetti, P Carloni, G Legname Journal of Biomolecular Structure and Dynamics 31 (8), 829-840, 2013 | 15 | 2013 |
Allosteric Modulation Mechanism of the mGluR5 Transmembrane Domain X Cong, JB Chéron, J Golebiowski, S Antonczak, S Fiorucci Journal of chemical information and modeling 59 (6), 2871-2878, 2019 | 14 | 2019 |