Synuclein activates microglia in a model of Parkinson's disease X Su, KA Maguire-Zeiss, R Giuliano, L Prifti, K Venkatesh, HJ Federoff Neurobiology of aging 29 (11), 1690-1701, 2008 | 543 | 2008 |
Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease BD Lee, JH Shin, J VanKampen, L Petrucelli, AB West, HS Ko, YI Lee, ... Nature medicine 16 (9), 998-1000, 2010 | 422 | 2010 |
Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders SG Daniele, D Béraud, C Davenport, K Cheng, H Yin, KA Maguire-Zeiss Science signaling 8 (376), ra45-ra45, 2015 | 269 | 2015 |
α-Synuclein alters toll-like receptor expression D Béraud, M Twomey, B Bloom, A Mittereder, V Ton, K Neitzke, ... Frontiers in neuroscience 5, 80, 2011 | 208 | 2011 |
Microglial activation and antioxidant responses induced by the Parkinson’s disease protein α-synuclein D Béraud, HA Hathaway, J Trecki, S Chasovskikh, DA Johnson, ... Journal of Neuroimmune Pharmacology 8, 94-117, 2013 | 204 | 2013 |
Preferential loss of preproenkephalin versus preprotachykinin neurons from the striatum of Huntington's disease patients EK Richfield, KA Maguire‐Zeiss, HE Vonkeman, P Voorn Annals of neurology 38 (6), 852-861, 1995 | 180 | 1995 |
Mutant α-synuclein overexpression mediates early proinflammatory activity X Su, HJ Federoff, KA Maguire-Zeiss Neurotoxicity research 16, 238-254, 2009 | 172 | 2009 |
Synuclein, dopamine and oxidative stress: co-conspirators in Parkinson's disease? KA Maguire-Zeiss, DW Short, HJ Federoff Molecular Brain Research 134 (1), 18-23, 2005 | 162 | 2005 |
Misfolded α-synuclein and toll-like receptors: therapeutic targets for Parkinson's disease D Béraud, KA Maguire-Zeiss Parkinsonism & related disorders 18, S17-S20, 2012 | 146 | 2012 |
Human interleukin-10 gene transfer is protective in a rat model of Parkinson's disease LC Johnston, X Su, K Maguire-Zeiss, K Horovitz, I Ankoudinova, ... Molecular Therapy 16 (8), 1392-1399, 2008 | 115 | 2008 |
Gene therapy in Parkinson’s disease: rationale and current status LR Feng, KA Maguire-Zeiss CNS drugs 24, 177-192, 2010 | 111 | 2010 |
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model PJ Khandelwal, SB Dumanis, LR Feng, K Maguire-Zeiss, GW Rebeck, ... Molecular neurodegeneration 5, 1-13, 2010 | 103 | 2010 |
The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse MH Savolainen, CT Richie, BK Harvey, PT Männistö, KA Maguire-Zeiss, ... Neurobiology of disease 68, 1-15, 2014 | 98 | 2014 |
Reduced expression of preproenkephalin in striatal neurons from Huntington's disease patients EK Richfield, KA Maguire‐Zeiss, C Cox, J Gilmore, P Voorn Annals of Neurology: Official Journal of the American Neurological …, 1995 | 98 | 1995 |
α‐Synuclein mediates alterations in membrane conductance: a potential role for α‐synuclein oligomers in cell vulnerability LR Feng, HJ Federoff, S Vicini, KA Maguire‐Zeiss European Journal of Neuroscience 32 (1), 10-17, 2010 | 94 | 2010 |
Methamphetamine‐associated cleavage of the synaptic adhesion molecule intercellular adhesion molecule‐5 K Conant, I Lonskaya, A Szklarczyk, C Krall, J Steiner, K Maguire‐Zeiss, ... Journal of neurochemistry 118 (4), 521-532, 2011 | 69 | 2011 |
Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector WJ Bowers, MA Mastrangelo, DF Howard, HA Southerland, ... Molecular Therapy 13 (3), 580-588, 2006 | 65 | 2006 |
Convergent pathobiologic model of Parkinson's disease KA MAGUIRE‐ZEISS, HJ Federoff Annals of the New York Academy of Sciences 991 (1), 152-166, 2003 | 65 | 2003 |
α-Synuclein: A therapeutic target for Parkinson’s disease? KA Maguire-Zeiss Pharmacological research 58 (5-6), 271-280, 2008 | 60 | 2008 |
Toll-like receptor 2 signaling and current approaches for therapeutic modulation in synucleinopathies IF Caplan, KA Maguire-Zeiss Frontiers in pharmacology 9, 417, 2018 | 58 | 2018 |