The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs T Tenev, K Bianchi, M Darding, M Broemer, C Langlais, F Wallberg, ... Molecular cell 43 (3), 432-448, 2011 | 928 | 2011 |
The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif LM Martins, I Iaccarino, T Tenev, S Gschmeissner, NF Totty, NR Lemoine, ... Journal of Biological Chemistry 277 (1), 439-444, 2002 | 733 | 2002 |
The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner J Zhao, T Tenev, LM Martins, J Downward, NR Lemoine Journal of cell science 113 (23), 4363-4371, 2000 | 434 | 2000 |
Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis M Marani, T Tenev, D Hancock, J Downward, NR Lemoine Molecular and cellular biology 22 (11), 3577-3589, 2002 | 417 | 2002 |
The developing human connectome project: A minimal processing pipeline for neonatal cortical surface reconstruction A Makropoulos, EC Robinson, A Schuh, R Wright, S Fitzgibbon, J Bozek, ... Neuroimage 173, 88-112, 2018 | 406 | 2018 |
IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis M Gyrd-Hansen, M Darding, M Miasari, MM Santoro, L Zender, W Xue, ... Nature cell biology 10 (11), 1309-1317, 2008 | 321 | 2008 |
Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis M Ditzel, R Wilson, T Tenev, A Zachariou, A Paul, E Deas, P Meier Nature cell biology 5 (5), 467-473, 2003 | 284 | 2003 |
MK2 phosphorylates RIPK1 to prevent TNF-induced cell death I Jaco, A Annibaldi, N Lalaoui, R Wilson, T Tenev, L Laurien, C Kim, ... Molecular cell 66 (5), 698-710. e5, 2017 | 278 | 2017 |
PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling N Lhocine, PS Ribeiro, N Buchon, A Wepf, R Wilson, T Tenev, B Lemaitre, ... Cell host & microbe 4 (2), 147-158, 2008 | 268 | 2008 |
IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms T Tenev, A Zachariou, R Wilson, M Ditzel, P Meier Nature cell biology 7 (1), 70-77, 2005 | 211 | 2005 |
Phosphotyrosine 1173 mediates binding of the protein-tyrosine phosphatase SHP-1 to the epidermal growth factor receptor and attenuation of receptor signaling H Keilhack, T Tenev, E Nyakatura, J Godovac-Zimmermann, L Nielsen, ... Journal of Biological Chemistry 273 (38), 24839-24846, 1998 | 211 | 1998 |
Inactivation of protein-tyrosine phosphatases as mechanism of UV-induced signal transduction S Groß, A Knebel, T Tenev, A Neininger, M Gaestel, P Herrlich, ... Journal of Biological Chemistry 274 (37), 26378-26386, 1999 | 209 | 1999 |
SUMO-mediated regulation of NLRP3 modulates inflammasome activity R Barry, SW John, G Liccardi, T Tenev, I Jaco, CH Chen, J Choi, ... Nature communications 9 (1), 3001, 2018 | 174 | 2018 |
Inactivation of effector caspases through nondegradative polyubiquitylation M Ditzel, M Broemer, T Tenev, C Bolduc, TV Lee, KTG Rigbolt, R Elliott, ... Molecular cell 32 (4), 540-553, 2008 | 150 | 2008 |
Role of Bim in the survival pathway induced by Raf in epithelial cells M Marani, D Hancock, R Lopes, T Tenev, J Downward, NR Lemoine Oncogene 23 (14), 2431-2441, 2004 | 147 | 2004 |
Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance LA Martin, R Ribas, N Simigdala, E Schuster, S Pancholi, T Tenev, ... Nature communications 8 (1), 1865, 2017 | 143 | 2017 |
Both SH2 domains are involved in interaction of SHP-1 with the epidermal growth factor receptor but cannot confer receptor-directed activity to SHP-1/SHP-2 chimera T Tenev, H Keilhack, S Tomic, B Stoyanov, M Stein-Gerlach, R Lammers, ... Journal of Biological Chemistry 272 (9), 5966-5973, 1997 | 139 | 1997 |
Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a caspase-9-mediated pathway IA McNeish, S Bell, T McKay, T Tenev, M Marani, NR Lemoine Experimental cell research 286 (2), 186-198, 2003 | 137 | 2003 |
CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration J Lopez, SW John, T Tenev, GJP Rautureau, MG Hinds, F Francalanci, ... Molecular cell 42 (5), 569-583, 2011 | 136 | 2011 |
Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling A Meinander, C Runchel, T Tenev, L Chen, CH Kim, PS Ribeiro, ... The EMBO journal 31 (12), 2770-2783, 2012 | 127 | 2012 |