An evolutionary perspective on field cancerization K Curtius, NA Wright, TA Graham Nature Reviews Cancer 18 (1), 19-32, 2018 | 422 | 2018 |
The 2019 mathematical oncology roadmap RC Rockne, A Hawkins-Daarud, KR Swanson, JP Sluka, JA Glazier, ... Physical biology 16 (4), 041005, 2019 | 177 | 2019 |
Evolutionary history of human colitis-associated colorectal cancer AM Baker, W Cross, K Curtius, I Al Bakir, CHR Choi, HL Davis, D Temko, ... Gut 68 (6), 985-995, 2019 | 143 | 2019 |
Impact of tumor progression on cancer incidence curves EG Luebeck, K Curtius, J Jeon, WD Hazelton Cancer research 73 (3), 1086-1096, 2013 | 97 | 2013 |
Exploring the recent trend in esophageal adenocarcinoma incidence and mortality using comparative simulation modeling CY Kong, S Kroep, K Curtius, WD Hazelton, J Jeon, R Meza, CR Heberle, ... Cancer epidemiology, biomarkers & prevention 23 (6), 997-1006, 2014 | 71 | 2014 |
The role of gastroesophageal reflux and other factors during progression to esophageal adenocarcinoma WD Hazelton, K Curtius, JM Inadomi, TL Vaughan, R Meza, ... Cancer Epidemiology, Biomarkers & Prevention 24 (7), 1012-1023, 2015 | 51 | 2015 |
Computational modelling suggests that Barrett’s oesophagus may be the precursor of all oesophageal adenocarcinomas K Curtius, JH Rubenstein, A Chak, JM Inadomi Gut 70 (8), 1435-1440, 2021 | 49 | 2021 |
The mutational signatures of formalin fixation on the human genome Q Guo, E Lakatos, IA Bakir, K Curtius, TA Graham, V Mustonen Nature Communications 13 (1), 4487, 2022 | 46 | 2022 |
Specific mechanisms of chromosomal instability indicate therapeutic sensitivities in high-grade serous ovarian carcinoma N Tamura, N Shaikh, D Muliaditan, TN Soliman, JR McGuinness, ... Cancer research 80 (22), 4946-4959, 2020 | 43 | 2020 |
A molecular clock infers heterogeneous tissue age among patients with Barrett’s esophagus K Curtius, CJ Wong, WD Hazelton, AM Kaz, A Chak, JE Willis, WM Grady, ... PLoS computational biology 12 (5), e1004919, 2016 | 40 | 2016 |
From colitis to cancer: an evolutionary trajectory that merges maths and biology I Al Bakir, K Curtius, TA Graham Frontiers in immunology 9, 2368, 2018 | 33 | 2018 |
Evolution of premalignant disease K Curtius, NA Wright, TA Graham Cold Spring Harbor Perspectives in Medicine 7 (12), a026542, 2017 | 33 | 2017 |
Implications of epigenetic drift in colorectal neoplasia GE Luebeck, WD Hazelton, K Curtius, SK Maden, M Yu, KT Carter, ... Cancer research 79 (3), 495-504, 2019 | 31 | 2019 |
A multiscale model evaluates screening for neoplasia in Barrett’s esophagus K Curtius, WD Hazelton, J Jeon, EG Luebeck PLoS computational biology 11 (5), e1004272, 2015 | 29 | 2015 |
Identification of a key role of widespread epigenetic drift in Barrett’s esophagus and esophageal adenocarcinoma EG Luebeck, K Curtius, WD Hazelton, S Maden, M Yu, PN Thota, DT Patil, ... Clinical epigenetics 9, 1-10, 2017 | 26 | 2017 |
Radiofrequency ablation of Barrett's esophagus reduces esophageal adenocarcinoma incidence and mortality in a comparative modeling analysis S Kroep, CR Heberle, K Curtius, CY Kong, I Lansdorp-Vogelaar, A Ali, ... Clinical Gastroenterology and Hepatology-The Official Clinical Practice …, 2017 | 24 | 2017 |
Multicentre derivation and validation of a colitis-associated colorectal cancer risk prediction web tool K Curtius, M Kabir, I Al Bakir, CHR Choi, JL Hartono, M Johnson, JE East, ... Gut 71 (4), 705-715, 2022 | 20 | 2022 |
Cancer's second genome: microbial cancer diagnostics and redefining clonal evolution as a multispecies process: humans and their tumors are not aseptic, and the multispecies … GD Sepich‐Poore, C Guccione, L Laplane, T Pradeu, K Curtius, R Knight BioEssays 44 (5), 2100252, 2022 | 14 | 2022 |
Lynch Syndrome—a mechanistic and clinical management update K Curtius, S Gupta, CR Boland Alimentary pharmacology & therapeutics 55 (8), 960-977, 2022 | 11 | 2022 |
Optimal timing for cancer screening and adaptive surveillance using mathematical modeling K Curtius, A Dewanji, WD Hazelton, JH Rubenstein, GE Luebeck Cancer research 81 (4), 1123-1134, 2021 | 8 | 2021 |