Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity W Zeng, L Sun, X Jiang, X Chen, F Hou, A Adhikari, M Xu, ZJ Chen Cell 141 (2), 315-330, 2010 | 682 | 2010 |
Direct activation of protein kinases by unanchored polyubiquitin chains ZP Xia, L Sun, X Chen, G Pineda, X Jiang, A Adhikari, W Zeng, ZJ Chen Nature 461 (7260), 114-119, 2009 | 645 | 2009 |
Sympathetic neuro-adipose connections mediate leptin-driven lipolysis W Zeng, RM Pirzgalska, MMA Pereira, N Kubasova, A Barateiro, E Seixas, ... Cell 163 (1), 84-94, 2015 | 506 | 2015 |
A genomic regulatory element that directs assembly and function of immune-specific AP-1–IRF complexes E Glasmacher, S Agrawal, AB Chang, TL Murphy, W Zeng, B Vander Lugt, ... Science 338 (6109), 975-980, 2012 | 378 | 2012 |
A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFα and IL-1β M Xu, B Skaug, W Zeng, ZJ Chen Molecular cell 36 (2), 302-314, 2009 | 274 | 2009 |
Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH17 cells S Rutz, R Noubade, C Eidenschenk, N Ota, W Zeng, Y Zheng, J Hackney, ... Nature immunology 12 (12), 1238-1245, 2011 | 236 | 2011 |
Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3 W Zeng, M Xu, S Liu, L Sun, ZJ Chen Molecular cell 36 (2), 315-325, 2009 | 191 | 2009 |
Dense intra-adipose sympathetic arborizations are essential for cold-induced beiging of mouse white adipose tissue H Jiang, X Ding, Y Cao, H Wang, W Zeng Cell metabolism 26 (4), 686-692. e3, 2017 | 190 | 2017 |
CNTF-STAT3-IL-6 axis mediates neuroinflammatory cascade across schwann cell-neuron-microglia Z Hu, N Deng, K Liu, N Zhou, Y Sun, W Zeng Cell reports 31 (7), 2020 | 102 | 2020 |
Whole-tissue 3D imaging reveals intra-adipose sympathetic plasticity regulated by NGF-TrkA signal in cold-induced beiging Y Cao, H Wang, W Zeng Protein & cell 9 (6), 527-539, 2018 | 76 | 2018 |
Sarm1/Myd88-5 regulates neuronal intrinsic immune response to traumatic axonal injuries Q Wang, S Zhang, T Liu, H Wang, K Liu, Q Wang, W Zeng Cell reports 23 (3), 716-724, 2018 | 74 | 2018 |
The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2 S Zhang, J Zhou, Y Zhang, T Liu, P Friedel, W Zhuo, S Somasekharan, ... Communications biology 4 (1), 226, 2021 | 67 | 2021 |
Three-dimensional volume fluorescence-imaging of vascular plasticity in adipose tissues Y Cao, H Wang, Q Wang, X Han, W Zeng Molecular metabolism 14, 71-81, 2018 | 60 | 2018 |
Structure of intact human MCU supercomplex with the auxiliary MICU subunits W Zhuo, H Zhou, R Guo, J Yi, L Zhang, L Yu, Y Sui, W Zeng, P Wang, ... Protein & Cell 12 (3), 220-229, 2021 | 47 | 2021 |
Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism S Zhang, N Li, W Zeng, N Gao, M Yang Protein & cell 8 (11), 834-847, 2017 | 47 | 2017 |
An immune-sympathetic neuron communication axis guides adipose tissue browning in cancer-associated cachexia H Xie, C Heier, X Meng, L Bakiri, I Pototschnig, Z Tang, S Schauer, ... Proceedings of the National Academy of Sciences 119 (9), e2112840119, 2022 | 39 | 2022 |
Interactions between central nervous system and peripheral metabolic organs W Zeng, F Yang, WL Shen, C Zhan, P Zheng, J Hu Science China Life Sciences 65 (10), 1929-1958, 2022 | 37 | 2022 |
Eosinophils regulate intra-adipose axonal plasticity X Meng, X Qian, X Ding, W Wang, X Yin, G Zhuang, W Zeng Proceedings of the National Academy of Sciences 119 (3), e2112281119, 2022 | 36 | 2022 |
MITAgating viral infection W Zeng, ZJ Chen Immunity 29 (4), 513-515, 2008 | 25 | 2008 |
DLK mediates the neuronal intrinsic immune response and regulates glial reaction and neuropathic pain Z Hu, N Deng, K Liu, W Zeng Experimental neurology 322, 113056, 2019 | 23 | 2019 |