Biomolecular condensates: organizers of cellular biochemistry SF Banani, HO Lee, AA Hyman, MK Rosen Nature reviews Molecular cell biology 18 (5), 285-298, 2017 | 4342 | 2017 |
Phase transitions in the assembly of multivalent signalling proteins P Li, S Banjade, HC Cheng, S Kim, B Chen, L Guo, M Llaguno, ... Nature 483 (7389), 336-340, 2012 | 2223 | 2012 |
Formation and maturation of phase-separated liquid droplets by RNA-binding proteins Y Lin, DSW Protter, MK Rosen, R Parker Molecular cell 60 (2), 208-219, 2015 | 1499 | 2015 |
Compositional control of phase-separated cellular bodies SF Banani, AM Rice, WB Peeples, Y Lin, S Jain, R Parker, MK Rosen Cell 166 (3), 651-663, 2016 | 1093 | 2016 |
Phase separation of signaling molecules promotes T cell receptor signal transduction X Su, JA Ditlev, E Hui, W Xing, S Banjade, J Okrut, DS King, J Taunton, ... Science 352 (6285), 595-599, 2016 | 1034 | 2016 |
Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein AS Kim, LT Kakalis, N Abdul-Manan, GA Liu, MK Rosen Nature 404 (6774), 151-158, 2000 | 958 | 2000 |
Organization of chromatin by intrinsic and regulated phase separation BA Gibson, LK Doolittle, MWG Schneider, LE Jensen, N Gamarra, ... Cell 179 (2), 470-484. e21, 2019 | 822 | 2019 |
Sequence determinants of intracellular phase separation by complex coacervation of a disordered protein CW Pak, M Kosno, AS Holehouse, SB Padrick, A Mittal, R Ali, AA Yunus, ... Molecular cell 63 (1), 72-85, 2016 | 690 | 2016 |
Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins TS Harmon, AS Holehouse, MK Rosen, RV Pappu elife 6, e30294, 2017 | 552 | 2017 |
Structure and control of the actin regulatory WAVE complex Z Chen, D Borek, SB Padrick, TS Gomez, Z Metlagel, AM Ismail, ... Nature 468 (7323), 533-538, 2010 | 545 | 2010 |
Phase transitions of multivalent proteins can promote clustering of membrane receptors S Banjade, MK Rosen elife 3, e04123, 2014 | 538 | 2014 |
A framework for understanding the functions of biomolecular condensates across scales AS Lyon, WB Peeples, MK Rosen Nature Reviews Molecular Cell Biology 22 (3), 215-235, 2021 | 524 | 2021 |
Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia K Devriendt, AS Kim, G Mathijs, SGM Frints, M Schwartz, JJ Van den Oord, ... Nature genetics 27 (3), 313-317, 2001 | 502 | 2001 |
Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain T Otomo, DR Tomchick, C Otomo, SC Panchal, M Machius, MK Rosen Nature 433 (7025), 488-494, 2005 | 483 | 2005 |
Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation B Aghazadeh, WE Lowry, XY Huang, MK Rosen Cell 102 (5), 625-633, 2000 | 475 | 2000 |
Solution structure of the SH3 domain of Src and identification of its ligand-binding site H Yu, MK Rosen, TB Shin, C Seidel-Dugan, JS Brugge, SL Schreiber Science 258 (5088), 1665-1668, 1992 | 451 | 1992 |
Structure of Cdc42 in complex with the GTPase-binding domain of the ‘Wiskott–Aldrich syndrome’protein N Abdul-Manan, B Aghazadeh, GA Liu, A Majumdar, O Ouerfelli, ... Nature 399 (6734), 379-383, 1999 | 430 | 1999 |
Stoichiometry controls activity of phase-separated clusters of actin signaling proteins LB Case, X Zhang, JA Ditlev, MK Rosen Science 363 (6431), 1093-1097, 2019 | 378 | 2019 |
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin SW Michnick, MK Rosen, TJ Wandless, M Karplus, SL Schreiber Science 252 (5007), 836-839, 1991 | 376 | 1991 |
Selective methyl group protonation of perdeuterated proteins MK Rosen, KH Gardner, RC Willis, WE Parris, T Pawson, LE Kay Journal of molecular biology 263 (5), 627-636, 1996 | 375 | 1996 |