| A pharmacological map of the PI3-K family defines a role for p110α in insulin signaling ZA Knight, B Gonzalez, ME Feldman, ER Zunder, DD Goldenberg, ... Cell 125 (4), 733-747, 2006 | 1411 | 2006 |
| Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 ME Feldman, B Apsel, A Uotila, R Loewith, ZA Knight, D Ruggero, ... PLoS biology 7 (2), e1000038, 2009 | 1356 | 2009 |
| T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR S Sauer, L Bruno, A Hertweck, D Finlay, M Leleu, M Spivakov, ZA Knight, ... Proceedings of the National Academy of Sciences 105 (22), 7797-7802, 2008 | 989 | 2008 |
| Targeting the cancer kinome through polypharmacology ZA Knight, H Lin, KM Shokat Nature Reviews Cancer 10 (2), 130-137, 2010 | 810 | 2010 |
| Features of selective kinase inhibitors ZA Knight, KM Shokat Chemistry & biology 12 (6), 621-637, 2005 | 808 | 2005 |
| A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma QW Fan, ZA Knight, DD Goldenberg, W Yu, KE Mostov, D Stokoe, ... Cancer cell 9 (5), 341-349, 2006 | 762 | 2006 |
| Sensory detection of food rapidly modulates arcuate feeding circuits Y Chen, YC Lin, TW Kuo, ZA Knight Cell 160 (5), 829-841, 2015 | 588 | 2015 |
| Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases B Apsel, JA Blair, B Gonzalez, TM Nazif, ME Feldman, B Aizenstein, ... Nature chemical biology 4 (11), 691, 2008 | 569 | 2008 |
| Regulation of body temperature by the nervous system CL Tan, ZA Knight Neuron 98 (1), 31-48, 2018 | 521 | 2018 |
| Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition OK Mirzoeva, D Das, LM Heiser, S Bhattacharya, D Siwak, R Gendelman, ... Cancer research 69 (2), 565-572, 2009 | 440 | 2009 |
| Warm-sensitive neurons that control body temperature CL Tan, EK Cooke, DE Leib, YC Lin, GE Daly, CA Zimmerman, ZA Knight Cell 167 (1), 47-59. e15, 2016 | 360 | 2016 |
| Hyperleptinemia is required for the development of leptin resistance ZA Knight, KS Hannan, ML Greenberg, JM Friedman PloS one 5 (6), e11376, 2010 | 353 | 2010 |
| Molecular profiling of activated neurons by phosphorylated ribosome capture ZA Knight, K Tan, K Birsoy, S Schmidt, JL Garrison, RW Wysocki, ... Cell 151 (5), 1126-1137, 2012 | 342 | 2012 |
| Phosphospecific proteolysis for mapping sites of protein phosphorylation ZA Knight, B Schilling, RH Row, DM Kenski, BW Gibson, KM Shokat Nature biotechnology 21 (9), 1047-1054, 2003 | 323 | 2003 |
| Genetic identification of vagal sensory neurons that control feeding L Bai, S Mesgarzadeh, KS Ramesh, EL Huey, Y Liu, LA Gray, TJ Aitken, ... Cell 179 (5), 1129-1143. e23, 2019 | 320 | 2019 |
| Chemical genetics: where genetics and pharmacology meet ZA Knight, KM Shokat Cell 128 (3), 425-430, 2007 | 296 | 2007 |
| Thirst neurons anticipate the homeostatic consequences of eating and drinking CA Zimmerman, YC Lin, DE Leib, L Guo, EL Huey, GE Daly, Y Chen, ... Nature 537 (7622), 680-684, 2016 | 276 | 2016 |
| Neural circuits underlying thirst and fluid homeostasis CA Zimmerman, DE Leib, ZA Knight Nature Reviews Neuroscience 18 (8), 459-469, 2017 | 267 | 2017 |
| Identification of preoptic sleep neurons using retrograde labelling and gene profiling S Chung, F Weber, P Zhong, CL Tan, TN Nguyen, KT Beier, N Hörmann, ... Nature 545 (7655), 477-481, 2017 | 262 | 2017 |
| A dual phosphoinositide-3-kinase α/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma QW Fan, CK Cheng, TP Nicolaides, CS Hackett, ZA Knight, KM Shokat, ... Cancer research 67 (17), 7960-7965, 2007 | 257 | 2007 |
