| CRISPR-engineered T cells in patients with refractory cancer EA Stadtmauer, JA Fraietta, MM Davis, AD Cohen, KL Weber, E Lancaster, ... Science 367 (6481), eaba7365, 2020 | 1169 | 2020 |
| Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells JA Fraietta, CL Nobles, MA Sammons, S Lundh, SA Carty, TJ Reich, ... Nature 558 (7709), 307-312, 2018 | 709 | 2018 |
| A quantitative approach for measuring the reservoir of latent HIV-1 proviruses KM Bruner, Z Wang, FR Simonetti, AM Bender, KJ Kwon, S Sengupta, ... Nature 566 (7742), 120-125, 2019 | 574 | 2019 |
| Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell M Ruella, J Xu, DM Barrett, JA Fraietta, TJ Reich, DE Ambrose, ... Nature medicine 24 (10), 1499-1503, 2018 | 561 | 2018 |
| Decade-long leukaemia remissions with persistence of CD4+ CAR T cells JJ Melenhorst, GM Chen, M Wang, DL Porter, C Chen, MKA Collins, ... Nature 602 (7897), 503-509, 2022 | 529 | 2022 |
| PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial V Narayan, JS Barber-Rotenberg, IY Jung, SF Lacey, AJ Rech, MM Davis, ... Nature medicine 28 (4), 724-734, 2022 | 231 | 2022 |
| Antigen-driven clonal selection shapes the persistence of HIV-1–infected CD4+ T cells in vivo FR Simonetti, H Zhang, GP Soroosh, J Duan, K Rhodehouse, AL Hill, ... The Journal of clinical investigation 131 (3), 2021 | 129 | 2021 |
| CD19-targeting CAR T cell immunotherapy outcomes correlate with genomic modification by vector integration CL Nobles, S Sherrill-Mix, JK Everett, S Reddy, JA Fraietta, DL Porter, ... The Journal of Clinical Investigation 130 (2), 673-685, 2020 | 98 | 2020 |
| INSPIIRED: a pipeline for quantitative analysis of sites of new DNA integration in cellular genomes E Sherman, C Nobles, CC Berry, E Six, Y Wu, A Dryga, N Malani, F Male, ... Molecular Therapy-Methods & Clinical Development 4, 39-49, 2017 | 98 | 2017 |
| The theft of host heme by Gram-positive pathogenic bacteria CL Nobles, AW Maresso Metallomics 3 (8), 788-796, 2011 | 77 | 2011 |
| INSPIIRED: quantification and visualization tools for analyzing integration site distributions CC Berry, C Nobles, E Six, Y Wu, N Malani, E Sherman, A Dryga, ... Molecular Therapy Methods & Clinical Development 4, 17-26, 2017 | 67 | 2017 |
| Car t cell therapies with enhanced efficacy G Motz, FD Bushman, JA Fraietta, CH June, JJ Melenhorst, CL Nobles, ... US Patent App. 15/760,519, 2018 | 62 | 2018 |
| Clonal tracking in gene therapy patients reveals a diversity of human hematopoietic differentiation programs E Six, A Guilloux, A Denis, A Lecoules, A Magnani, R Vilette, F Male, ... Blood, The Journal of the American Society of Hematology 135 (15), 1219-1231, 2020 | 59 | 2020 |
| iGUIDE: an improved pipeline for analyzing CRISPR cleavage specificity CL Nobles, S Reddy, J Salas-McKee, X Liu, CH June, JJ Melenhorst, ... Genome biology 20, 1-6, 2019 | 53 | 2019 |
| Hal is a Bacillus anthracis heme acquisition protein MA Balderas, CL Nobles, ES Honsa, ER Alicki, AW Maresso Journal of bacteriology 194 (20), 5513-5521, 2012 | 48 | 2012 |
| Long-term remission despite clonal expansion of replication-competent HIV-1 isolates RT Veenhuis, AK Kwaa, CC Garliss, R Latanich, M Salgado, ... JCI insight 3 (18), 2018 | 47 | 2018 |
| A product of heme catabolism modulates bacterial function and survival CL Nobles, SI Green, AW Maresso PLoS pathogens 9 (7), e1003507, 2013 | 37 | 2013 |
| Impact of LEDGIN treatment during virus production on residual HIV-1 transcription G Vansant, LS Vranckx, I Zurnic, D Van Looveren, P Van de Velde, ... Retrovirology 16, 1-17, 2019 | 32 | 2019 |
| Combining random gene fission and rational gene fusion to discover near-infrared fluorescent protein fragments that report on protein–protein interactions N Pandey, CL Nobles, L Zechiedrich, AW Maresso, JJ Silberg ACS Synthetic Biology 4 (5), 615-624, 2015 | 26 | 2015 |
| A more efficient CRISPR-Cas12a variant derived from Lachnospiraceae bacterium MA2020 MH Tran, H Park, CL Nobles, P Karunadharma, L Pan, G Zhong, H Wang, ... Molecular Therapy-Nucleic Acids 24, 40-53, 2021 | 25 | 2021 |
