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Dehui Zhang
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年份
Detection of protein S‐sulfhydration by a tag‐switch technique
D Zhang, I Macinkovic, NO Devarie‐Baez, J Pan, CM Park, KS Carroll, ...
Angewandte Chemie International Edition 53 (2), 575-581, 2014
3002014
UNC2025, a Potent and Orally Bioavailable MER/FLT3 Dual Inhibitor
W Zhang, D DeRyckere, D Hunter, J Liu, MA Stashko, KA Minson, ...
Journal of medicinal chemistry 57 (16), 7031-7041, 2014
1612014
Methylsulfonyl benzothiazole (MSBT): a selective protein thiol blocking reagent
D Zhang, NO Devarie-Baez, Q Li, JR Lancaster Jr, M Xian
Organic letters 14 (13), 3396-3399, 2012
1202012
TAM family receptor kinase inhibition reverses MDSC-mediated suppression and augments anti–PD-1 therapy in melanoma
A Holtzhausen, W Harris, E Ubil, DM Hunter, J Zhao, Y Zhang, D Zhang, ...
Cancer immunology research 7 (10), 1672-1686, 2019
1072019
Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors
W Zhang, D Zhang, MA Stashko, D DeRyckere, D Hunter, D Kireev, ...
Journal of medicinal chemistry 56 (23), 9683-9692, 2013
842013
Reductive Ligation Mediated One-Step Disulfide Formation of S-Nitrosothiols
J Zhang, S Li, D Zhang, H Wang, AR Whorton, M Xian
Organic letters 12 (18), 4208-4211, 2010
692010
Small molecule inhibition of MERTK is efficacious in non–small cell lung cancer models independent of driver oncogene status
CT Cummings, W Zhang, KD Davies, GD Kirkpatrick, D Zhang, ...
Molecular cancer therapeutics 14 (9), 2014-2022, 2015
672015
An enantioselective nucleophilic addition of α, β-unsaturated trifluoromethylketones catalyzed by l-proline derivatives
D Zhang, C Yuan
Tetrahedron 64 (10), 2480-2488, 2008
592008
Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia
AB Lee-Sherick, W Zhang, KK Menachof, AA Hill, S Rinella, G Kirkpatrick, ...
Oncotarget 6 (9), 6722, 2015
522015
Direct methods for detection of protein S-nitrosylation
NO Devarie-Baez, D Zhang, S Li, AR Whorton, M Xian
Methods 62 (2), 171-176, 2013
462013
A Concise and First Synthesis of α‐Aminophosphinates with Two Stereogenic Atoms Leading to Optically Pure α‐Amino‐H‐phosphinic Acids
D Zhang, C Yuan
Chemistry–A European Journal 14 (20), 6049-6052, 2008
362008
Discovery of arylsulfonamides as dual orexin receptor agonists
D Zhang, DA Perrey, AM Decker, TL Langston, V Mavanji, DL Harris, ...
Journal of medicinal chemistry 64 (12), 8806-8825, 2021
262021
Highly selective MERTK inhibitors achieved by a single methyl group
J Zhao, D Zhang, W Zhang, MA Stashko, D DeRyckere, E Vasileiadi, ...
Journal of Medicinal Chemistry 61 (22), 10242-10254, 2018
262018
Reaction of 1, 2‐Unsaturated Trifluoromethyl Ketones and Their Conversion to 1‐(Trifluoromethyl) furan Derivatives
D Zhang, C Yuan
European journal of organic chemistry 2007 (23), 3916-3924, 2007
252007
One-Pot Thioether Formation from S-Nitrosothiols
D Zhang, NO Devarie-Baez, J Pan, H Wang, M Xian
Organic letters 12 (24), 5674-5676, 2010
212010
Data-driven construction of antitumor agents with controlled polypharmacology
C Da, D Zhang, M Stashko, E Vasileiadi, RE Parker, KA Minson, MG Huey, ...
Journal of the American Chemical Society 141 (39), 15700-15709, 2019
142019
General and cost-effective synthesis of 1-heteroaryl/arylcycloalkylamines and their broad applications
D Zhang, H Zheng, X Wang
Tetrahedron 72 (16), 1941-1953, 2016
112016
Mertk-specific pyrimidine compounds
X Wang, D Zhang, S Frye, D Kireev
US Patent App. 14/678,540, 2015
72015
Detektion von Persulfidbildung an Proteinen (S‐Sulfhydrierung) mithilfe einer Tag‐Switch‐Technik
D Zhang, I Macinkovic, NO Devarie‐Baez, J Pan, CM Park, KS Carroll, ...
Angewandte Chemie 126 (2), 586-592, 2014
72014
Isoquinolone derivatives as lysophosphatidic acid receptor 5 (LPA5) antagonists: Investigation of structure-activity relationships, ADME properties and analgesic effects
D Zhang, AM Decker, K Woodhouse, R Snyder, P Patel, DL Harris, ...
European journal of medicinal chemistry 243, 114741, 2022
52022
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