Detection of protein S‐sulfhydration by a tag‐switch technique D Zhang, I Macinkovic, NO Devarie‐Baez, J Pan, CM Park, KS Carroll, ... Angewandte Chemie International Edition 53 (2), 575-581, 2014 | 300 | 2014 |
UNC2025, a Potent and Orally Bioavailable MER/FLT3 Dual Inhibitor W Zhang, D DeRyckere, D Hunter, J Liu, MA Stashko, KA Minson, ... Journal of medicinal chemistry 57 (16), 7031-7041, 2014 | 161 | 2014 |
Methylsulfonyl benzothiazole (MSBT): a selective protein thiol blocking reagent D Zhang, NO Devarie-Baez, Q Li, JR Lancaster Jr, M Xian Organic letters 14 (13), 3396-3399, 2012 | 120 | 2012 |
TAM family receptor kinase inhibition reverses MDSC-mediated suppression and augments anti–PD-1 therapy in melanoma A Holtzhausen, W Harris, E Ubil, DM Hunter, J Zhao, Y Zhang, D Zhang, ... Cancer immunology research 7 (10), 1672-1686, 2019 | 107 | 2019 |
Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors W Zhang, D Zhang, MA Stashko, D DeRyckere, D Hunter, D Kireev, ... Journal of medicinal chemistry 56 (23), 9683-9692, 2013 | 84 | 2013 |
Reductive Ligation Mediated One-Step Disulfide Formation of S-Nitrosothiols J Zhang, S Li, D Zhang, H Wang, AR Whorton, M Xian Organic letters 12 (18), 4208-4211, 2010 | 69 | 2010 |
Small molecule inhibition of MERTK is efficacious in non–small cell lung cancer models independent of driver oncogene status CT Cummings, W Zhang, KD Davies, GD Kirkpatrick, D Zhang, ... Molecular cancer therapeutics 14 (9), 2014-2022, 2015 | 67 | 2015 |
An enantioselective nucleophilic addition of α, β-unsaturated trifluoromethylketones catalyzed by l-proline derivatives D Zhang, C Yuan Tetrahedron 64 (10), 2480-2488, 2008 | 59 | 2008 |
Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia AB Lee-Sherick, W Zhang, KK Menachof, AA Hill, S Rinella, G Kirkpatrick, ... Oncotarget 6 (9), 6722, 2015 | 52 | 2015 |
Direct methods for detection of protein S-nitrosylation NO Devarie-Baez, D Zhang, S Li, AR Whorton, M Xian Methods 62 (2), 171-176, 2013 | 46 | 2013 |
A Concise and First Synthesis of α‐Aminophosphinates with Two Stereogenic Atoms Leading to Optically Pure α‐Amino‐H‐phosphinic Acids D Zhang, C Yuan Chemistry–A European Journal 14 (20), 6049-6052, 2008 | 36 | 2008 |
Discovery of arylsulfonamides as dual orexin receptor agonists D Zhang, DA Perrey, AM Decker, TL Langston, V Mavanji, DL Harris, ... Journal of medicinal chemistry 64 (12), 8806-8825, 2021 | 26 | 2021 |
Highly selective MERTK inhibitors achieved by a single methyl group J Zhao, D Zhang, W Zhang, MA Stashko, D DeRyckere, E Vasileiadi, ... Journal of Medicinal Chemistry 61 (22), 10242-10254, 2018 | 26 | 2018 |
Reaction of 1, 2‐Unsaturated Trifluoromethyl Ketones and Their Conversion to 1‐(Trifluoromethyl) furan Derivatives D Zhang, C Yuan European journal of organic chemistry 2007 (23), 3916-3924, 2007 | 25 | 2007 |
One-Pot Thioether Formation from S-Nitrosothiols D Zhang, NO Devarie-Baez, J Pan, H Wang, M Xian Organic letters 12 (24), 5674-5676, 2010 | 21 | 2010 |
Data-driven construction of antitumor agents with controlled polypharmacology C Da, D Zhang, M Stashko, E Vasileiadi, RE Parker, KA Minson, MG Huey, ... Journal of the American Chemical Society 141 (39), 15700-15709, 2019 | 14 | 2019 |
General and cost-effective synthesis of 1-heteroaryl/arylcycloalkylamines and their broad applications D Zhang, H Zheng, X Wang Tetrahedron 72 (16), 1941-1953, 2016 | 11 | 2016 |
Mertk-specific pyrimidine compounds X Wang, D Zhang, S Frye, D Kireev US Patent App. 14/678,540, 2015 | 7 | 2015 |
Detektion von Persulfidbildung an Proteinen (S‐Sulfhydrierung) mithilfe einer Tag‐Switch‐Technik D Zhang, I Macinkovic, NO Devarie‐Baez, J Pan, CM Park, KS Carroll, ... Angewandte Chemie 126 (2), 586-592, 2014 | 7 | 2014 |
Isoquinolone derivatives as lysophosphatidic acid receptor 5 (LPA5) antagonists: Investigation of structure-activity relationships, ADME properties and analgesic effects D Zhang, AM Decker, K Woodhouse, R Snyder, P Patel, DL Harris, ... European journal of medicinal chemistry 243, 114741, 2022 | 5 | 2022 |