| In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy I Matic, M van Hagen, J Schimmel, B Macek, SC Ogg, MH Tatham, ... Molecular & cellular proteomics 7 (1), 132-144, 2008 | 370 | 2008 |
| Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif I Matic, J Schimmel, IA Hendriks, MA van Santen, F van de Rijke, ... Molecular cell 39 (4), 641-652, 2010 | 362 | 2010 |
| Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance D Zatreanu, HMR Robinson, O Alkhatib, M Boursier, H Finch, L Geo, ... Nature communications 12 (1), 3636, 2021 | 231 | 2021 |
| Uncovering SUMOylation dynamics during cell-cycle progression reveals FoxM1 as a key mitotic SUMO target protein J Schimmel, K Eifler, JO Sigurðsson, SAG Cuijpers, IA Hendriks, ... Molecular cell 53 (6), 1053-1066, 2014 | 198 | 2014 |
| The ubiquitin-proteasome system is a key component of the SUMO-2/3 cycle J Schimmel, KM Larsen, I Matic, M van Hagen, J Cox, M Mann, ... Molecular & Cellular Proteomics 7 (11), 2107-2122, 2008 | 183 | 2008 |
| MEF2 activates a genetic program promoting chamber dilation and contractile dysfunction in calcineurin-induced heart failure RJ van Oort, E van Rooij, M Bourajjaj, J Schimmel, MA Jansen, ... Circulation 114 (4), 298-308, 2006 | 160 | 2006 |
| Mutational signatures of non‐homologous and polymerase theta‐mediated end‐joining in embryonic stem cells J Schimmel, H Kool, R van Schendel, M Tijsterman The EMBO journal 36 (24), 3634-3649, 2017 | 134 | 2017 |
| Templated insertions: a smoking gun for polymerase theta-mediated end joining J Schimmel, R van Schendel, JT den Dunnen, M Tijsterman Trends in Genetics 35 (9), 632-644, 2019 | 133 | 2019 |
| Inactivation of Pol θ and C-NHEJ eliminates off-target integration of exogenous DNA AN Zelensky, J Schimmel, H Kool, R Kanaar, M Tijsterman Nature communications 8 (1), 66, 2017 | 125 | 2017 |
| RNF12 controls embryonic stem cell fate and morphogenesis in zebrafish embryos by targeting Smad7 for degradation L Zhang, H Huang, FF Zhou, J Schimmel, CG Pardo, T Zhang, TS Barakat, ... Molecular cell 46 (5), 650-661, 2012 | 96 | 2012 |
| Ubiquitin-specific protease 11 (USP11) deubiquitinates hybrid small ubiquitin-like modifier (SUMO)-ubiquitin chains to counteract RING finger protein 4 (RNF4) IA Hendriks, J Schimmel, K Eifler, JV Olsen, ACO Vertegaal Journal of Biological Chemistry 290 (25), 15526-15537, 2015 | 47 | 2015 |
| Telomeric DNA mediates de novo PML body formation AK Brouwer, J Schimmel, JCAG Wiegant, ACO Vertegaal, HJ Tanke, ... Molecular biology of the cell 20 (22), 4804-4815, 2009 | 46 | 2009 |
| Transcription-coupled nucleotide excision repair is coordinated by ubiquitin and SUMO in response to ultraviolet irradiation F Liebelt, J Schimmel, M Verlaan–de Vries, E Klemann, ME van Royen, ... Nucleic Acids Research 48 (1), 231-248, 2020 | 31 | 2020 |
| Small tandem DNA duplications result from CST-guided Pol α-primase action at DNA break termini J Schimmel, N Muñoz-Subirana, H Kool, R van Schendel, M Tijsterman Nature Communications 12 (1), 4843, 2021 | 27 | 2021 |
| Modulating mutational outcomes and improving precise gene editing at CRISPR-Cas9-induced breaks by chemical inhibition of end-joining pathways J Schimmel, N Munoz-Subirana, H Kool, R van Schendel, S van der Vlies, ... Cell Reports 42 (2), 2023 | 24 | 2023 |
| Positively charged amino acids flanking a sumoylation consensus tetramer on the 110 kDa tri-snRNP component SART1 enhance sumoylation efficiency J Schimmel, CIA Balog, AM Deelder, JW Drijfhout, PJ Hensbergen, ... Journal of proteomics 73 (8), 1523-1534, 2010 | 13 | 2010 |
| SIQ: easy quantitative measurement of mutation profiles in sequencing data R van Schendel, J Schimmel, M Tijsterman NAR genomics and bioinformatics 4 (3), lqac063, 2022 | 11 | 2022 |
| High-resolution breakpoint junction mapping of proximally extended D4Z4 deletions in FSHD1 reveals evidence for a founder effect RJLF Lemmers, PJ van der Vliet, DSL Granado, N van der Stoep, ... Human Molecular Genetics 31 (5), 748-760, 2022 | 11 | 2022 |
| Divergent molecular and cellular responses to low and high-dose ionizing radiation B Sampadi, S Vermeulen, B Mišovic, JJ Boei, TS Batth, JG Chang, ... Cells 11 (23), 3794, 2022 | 8 | 2022 |
| Chromosomal breaks at the origin of small tandem DNA duplications J Schimmel, MD van Wezel, R van Schendel, M Tijsterman BioEssays 45 (1), 2200168, 2023 | 3 | 2023 |
