Broad betacoronavirus neutralization by a stem helix–specific human antibody D Pinto, MM Sauer, N Czudnochowski, JS Low, MA Tortorici, MP Housley, ... Science 373 (6559), 1109-1116, 2021 | 292 | 2021 |
Human gene essentiality I Bartha, J Di Iulio, JC Venter, A Telenti Nature Reviews Genetics 19 (1), 51-62, 2018 | 233 | 2018 |
Broad sarbecovirus neutralization by a human monoclonal antibody MA Tortorici, N Czudnochowski, TN Starr, R Marzi, AC Walls, F Zatta, ... Nature 597 (7874), 103-108, 2021 | 206 | 2021 |
24 hours in the life of HIV-1 in a T cell line P Mohammadi, S Desfarges, I Bartha, B Joos, N Zangger, M Munoz, ... PLoS pathogens 9 (1), e1003161, 2013 | 188 | 2013 |
Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load PJ McLaren, C Coulonges, I Bartha, TL Lenz, AJ Deutsch, A Bashirova, ... Proceedings of the National Academy of Sciences 112 (47), 14658-14663, 2015 | 180 | 2015 |
The human noncoding genome defined by genetic diversity J Di Iulio, I Bartha, EHM Wong, HC Yu, V Lavrenko, D Yang, I Jung, ... Nature genetics 50 (3), 333-337, 2018 | 158 | 2018 |
A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control I Bartha, JM Carlson, CJ Brumme, PJ McLaren, ZL Brumme, M John, ... elife 2, e01123, 2013 | 139 | 2013 |
Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans L Westera, J Drylewicz, I Den Braber, T Mugwagwa, I Van Der Maas, ... Blood, The Journal of the American Society of Hematology 122 (13), 2205-2212, 2013 | 138 | 2013 |
Severe viral respiratory infections in children with IFIH1 loss-of-function mutations S Asgari, LJ Schlapbach, S Anchisi, C Hammer, I Bartha, T Junier, ... Proceedings of the National Academy of Sciences 114 (31), 8342-8347, 2017 | 136 | 2017 |
Predicting the mutational drivers of future SARS-CoV-2 variants of concern MC Maher, I Bartha, S Weaver, J Di Iulio, E Ferri, L Soriaga, FA Lempp, ... Science translational medicine 14 (633), eabk3445, 2022 | 130 | 2022 |
Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus MA Ansari, V Pedergnana, C LC Ip, A Magri, A Von Delft, D Bonsall, ... Nature genetics 49 (5), 666-673, 2017 | 126 | 2017 |
Dynamics of HIV latency and reactivation in a primary CD4+ T cell model P Mohammadi, J Di Iulio, M Munoz, R Martinez, I Bartha, M Cavassini, ... PLoS pathogens 10 (5), e1004156, 2014 | 100 | 2014 |
Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults BA Perkins, CT Caskey, P Brar, E Dec, DS Karow, AM Kahn, YCC Hou, ... Proceedings of the National Academy of Sciences 115 (14), 3686-3691, 2018 | 99 | 2018 |
Risk assessment and seroprevalence of SARS-CoV-2 infection in healthcare workers of COVID-19 and non-COVID-19 hospitals in Southern Switzerland L Piccoli, P Ferrari, G Piumatti, S Jovic, BF Rodriguez, F Mele, ... The Lancet Regional Health–Europe 1, 2021 | 85 | 2021 |
Amino acid variation in HLA class II proteins is a major determinant of humoral response to common viruses C Hammer, M Begemann, PJ McLaren, I Bartha, A Michel, B Klose, ... The American Journal of Human Genetics 97 (5), 738-743, 2015 | 71 | 2015 |
Mapping of positive selection sites in the HIV-1 genome in the context of RNA and protein structural constraints J Snoeck, J Fellay, I Bartha, DC Douek, A Telenti, JS Joke, JF Jacques, ... Retrovirology 8 (1), 87, 2011 | 64 | 2011 |
Structural insights into the Trp‐Cage folding intermediate formation P Rovó, P Stráner, A Láng, I Bartha, K Huszár, L Nyitray, A Perczel Chemistry–A European Journal 19 (8), 2628-2640, 2013 | 59 | 2013 |
Privacy-preserving genomic testing in the clinic: a model using HIV treatment PJ McLaren, JL Raisaro, M Aouri, M Rotger, E Ayday, I Bartha, ... Genetics in medicine 18 (8), 814-822, 2016 | 53 | 2016 |
Analysis of stop-gain and frameshift variants in human innate immunity genes A Rausell, P Mohammadi, PJ McLaren, I Bartha, I Xenarios, J Fellay, ... PLoS computational biology 10 (7), e1003757, 2014 | 41 | 2014 |
The characteristics of heterozygous protein truncating variants in the human genome I Bartha, A Rausell, PJ McLaren, P Mohammadi, M Tardaguila, ... PLoS computational biology 11 (12), e1004647, 2015 | 38 | 2015 |