Mechanisms of action of CD20 antibodies P Boross, JHW Leusen American journal of cancer research 2 (6), 676, 2012 | 347 | 2012 |
Neutrophils kill antibody-opsonized cancer cells by trogoptosis HL Matlung, L Babes, XW Zhao, M van Houdt, LW Treffers, DJ van Rees, ... Cell reports 23 (13), 3946-3959. e6, 2018 | 344 | 2018 |
The therapeutic CD38 monoclonal antibody daratumumab induces programmed cell death via Fcγ receptor–mediated cross-linking MB Overdijk, JH Jansen, M Nederend, JJ Lammerts van Bueren, ... The Journal of Immunology 197 (3), 807-813, 2016 | 301 | 2016 |
Glycoengineered CD20 antibody obinutuzumab activates neutrophils and mediates phagocytosis through CD16B more efficiently than rituximab J Golay, F Da Roit, L Bologna, C Ferrara, JH Leusen, A Rambaldi, C Klein, ... Blood, The Journal of the American Society of Hematology 122 (20), 3482-3491, 2013 | 285 | 2013 |
Crosstalk between human IgG isotypes and murine effector cells MB Overdijk, S Verploegen, A Ortiz Buijsse, T Vink, JHW Leusen, ... The Journal of Immunology 189 (7), 3430-3438, 2012 | 265 | 2012 |
Mac-1 (CD11b/CD18) is essential for Fc receptor–mediated neutrophil cytotoxicity and immunologic synapse formation AB van Spriel, JHW Leusen, M van Egmond, HBPM Dijkman, ... Blood, The Journal of the American Society of Hematology 97 (8), 2478-2486, 2001 | 257 | 2001 |
Functional characteristics of the high affinity IgG receptor, FcγRI CE van der Poel, RM Spaapen, JGJ van de Winkel, JHW Leusen The Journal of Immunology 186 (5), 2699-2704, 2011 | 213 | 2011 |
Effects of bovine immunoglobulins on immune function, allergy, and infection LH Ulfman, JHW Leusen, HFJ Savelkoul, JO Warner, RJJ Van Neerven Frontiers in nutrition 5, 52, 2018 | 192 | 2018 |
Glutaminyl cyclase is an enzymatic modifier of the CD47-SIRPα axis and a target for cancer immunotherapy MEW Logtenberg, JHM Jansen, M Raaben, M Toebes, K Franke, ... Nature medicine 25 (4), 612-619, 2019 | 181 | 2019 |
In vivo Cytotoxicity of Type I CD20 Antibodies Critically Depends on Fc Receptor ITAM Signaling S de Haij, JHM Jansen, P Boross, FJ Beurskens, JE Bakema, DL Bos, ... Cancer research 70 (8), 3209-3217, 2010 | 156 | 2010 |
Interactions between the components of the human NADPH oxidase: intrigues in the phox family JHW Leusen, AJ Verhoeven, D Roos Journal of Laboratory and Clinical Medicine 128 (5), 461-476, 1996 | 156 | 1996 |
Invited review: Neisseria meningitidis lipopolysaccharides in human pathology P Brandtzaeg, A Bjerre, R Øvstebø, B Brusletto, GB Joø, P Kierulf Journal of endotoxin research 7 (6), 401-420, 2001 | 150 | 2001 |
RhoB mediates phosphoantigen recognition by Vγ9Vδ2 T cell receptor Z Sebestyen, W Scheper, A Vyborova, S Gu, Z Rychnavska, M Schiffler, ... Cell reports 15 (9), 1973-1985, 2016 | 144 | 2016 |
Targeted delivery of a sialic acid-blocking glycomimetic to cancer cells inhibits metastatic spread C Bull, TJ Boltje, EAW van Dinther, T Peters, AMA de Graaf, JHW Leusen, ... ACS nano 9 (1), 733-745, 2015 | 142 | 2015 |
The high-affinity IgG receptor, FcγRI, plays a central role in antibody therapy of experimental melanoma L Bevaart, MJH Jansen, MJ van Vugt, JS Verbeek, JGJ van de Winkel, ... Cancer research 66 (3), 1261-1264, 2006 | 141 | 2006 |
156Pro--> Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and … JH Leusen, BG Bolscher, PM Hilarius, RS Weening, W Kaulfersch, ... The Journal of experimental medicine 180 (6), 2329-2334, 1994 | 137 | 1994 |
IgA EGFR antibodies mediate tumour killing in vivo P Boross, S Lohse, M Nederend, JHM Jansen, G van Tetering, M Dechant, ... EMBO molecular medicine 5 (8), 1213-1226, 2013 | 129 | 2013 |
A point mutation in gp91-phox of cytochrome b558 of the human NADPH oxidase leading to defective translocation of the cytosolic proteins p47-phox and p67-phox. JH Leusen, M De Boer, BG Bolscher, PM Hilarius, RS Weening, HD Ochs, ... The Journal of clinical investigation 93 (5), 2120-2126, 1994 | 125 | 1994 |
Potent Fc receptor signaling by IgA leads to superior killing of cancer cells by neutrophils compared to IgG AM Brandsma, S Bondza, M Evers, R Koutstaal, M Nederend, ... Frontiers in immunology 10, 704, 2019 | 123 | 2019 |
Prevalence, genetics and clinical presentation of chronic granulomatous disease in Sweden A Åhlin, M De Boer, D Roos, J Leusen, CIE Smith, U Sundin, H Rabbani, ... Acta paediatrica 84 (12), 1386-1394, 1995 | 123 | 1995 |