Structure of nitric oxide synthase oxygenase dimer with pterin and substrate BR Crane, AS Arvai, DK Ghosh, C Wu, ED Getzoff, DJ Stuehr, JA Tainer Science 279 (5359), 2121-2126, 1998 | 858 | 1998 |
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes BR Crane, AS Arvai, R Gachhui, C Wu, DK Ghosh, ED Getzoff, DJ Stuehr, ... Science 278 (5337), 425-431, 1997 | 465 | 1997 |
Macrophage NO synthase: characterization of isolated oxygenase and reductase domains reveals a head-to-head subunit interaction DK Ghosh, DJ Stuehr Biochemistry 34 (3), 801-807, 1995 | 229 | 1995 |
Characterization of the inducible nitric oxide synthase oxygenase domain identifies a 49 amino acid segment required for subunit dimerization and tetrahydrobiopterin interaction DK Ghosh, C Wu, E Pitters, M Moloney, ER Werner, B Mayer, DJ Stuehr Biochemistry 36 (35), 10609-10619, 1997 | 189 | 1997 |
Nitric oxide synthases: domain structure and alignment in enzyme function and control DK Ghosh, JC Salerno Front Biosci 8 (24), 193-209, 2003 | 182 | 2003 |
Characterization of the reductase domain of rat neuronal nitric oxide synthase generated in the methylotrophic yeast Pichia pastoris: calmodulin response is complete within the … R Gachhui, A Presta, DF Bentley, HM Abu-Soud, R McArthur, G Brudvig, ... Journal of Biological Chemistry 271 (34), 20594-20602, 1996 | 179 | 1996 |
N‐terminal domain swapping and metal ion binding in nitric oxide synthase dimerization BR Crane, RJ Rosenfeld, AS Arvai, DK Ghosh, S Ghosh, JA Tainer, ... The EMBO journal, 1999 | 133 | 1999 |
Stopped-flow analysis of CO and NO binding to inducible nitric oxide synthase HM Abu-Soud, C Wu, DK Ghosh, DJ Stuehr Biochemistry 37 (11), 3777-3786, 1998 | 133 | 1998 |
Heme Iron Reduction and Catalysis by a Nitric Oxide Synthase Heterodimer Containing One Reductase and Two Oxygenase Domains (∗) U Siddhanta, C Wu, HM Abu-Soud, J Zhang, DK Ghosh, DJ Stuehr Journal of Biological Chemistry 271 (13), 7309-7312, 1996 | 126 | 1996 |
High-level expression of mouse inducible nitric oxide synthase inEscherichia colirequires coexpression with calmodulin C Wu, J Zhang, H Abu-Soud, DK Ghosh, DJ Stuehr Biochemical and biophysical research communications 222 (2), 439-444, 1996 | 111 | 1996 |
Mutagenesis of acidic residues in the oxygenase domain of inducible nitric-oxide synthase identifies a glutamate involved in arginine binding R Gachhui, DK Ghosh, C Wu, J Parkinson, BR Crane, DJ Stuehr Biochemistry 36 (17), 5097-5103, 1997 | 98 | 1997 |
Domains of macrophage NO synthase have divergent roles in forming and stabilizing the active dimeric enzyme DK Ghosh, HM Abu-Soud, DJ Stuehr Biochemistry 35 (5), 1444-1449, 1996 | 96 | 1996 |
Structural Basis for the Specificity of the Nitric-oxide Synthase Inhibitors W1400 and N ω-Propyl-l-Arg for the Inducible and Neuronal Isoforms R Fedorov, E Hartmann, DK Ghosh, I Schlichting Journal of Biological Chemistry 278 (46), 45818-45825, 2003 | 89 | 2003 |
Inhibition of nitric oxide synthase by cobalamins and cobinamides JB Weinberg, Y Chen, N Jiang, BE Beasley, JC Salerno, DK Ghosh Free Radical Biology and Medicine 46 (12), 1626-1632, 2009 | 85 | 2009 |
Inducible nitric oxide synthase: role of the N‐terminal β‐hairpin hook and pterin‐binding segment in dimerization and tetrahydrobiopterin interaction DK Ghosh, BR Crane, S Ghosh, D Wolan, R Gachhui, C Crooks, A Presta, ... The EMBO Journal, 1999 | 81 | 1999 |
Crystal structures of cyanide complexes of P450cam and the oxygenase domain of inducible nitric oxide synthase—structural models of the short-lived oxygen complexes R Fedorov, DK Ghosh, I Schlichting Archives of biochemistry and biophysics 409 (1), 25-31, 2003 | 74 | 2003 |
Reconstitution of the second step in NO synthesis using the isolated oxygenase and reductase domains of macrophage NO synthase DK Ghosh, HM Abu-Soud, DJ Stuehr Biochemistry 34 (36), 11316-11320, 1995 | 74 | 1995 |
Differential activation of nitric-oxide synthase isozymes by calmodulin-troponin C chimeras E Newman, DE Spratt, J Mosher, B Cheyne, HJ Montgomery, DL Wilson, ... Journal of Biological Chemistry 279 (32), 33547-33557, 2004 | 70 | 2004 |
Structures of nitric oxide synthase isoforms complexed with the inhibitor AR-R17477 suggest a rational basis for specificity and inhibitor design R Fedorov, R Vasan, DK Ghosh, I Schlichting Proceedings of the National Academy of Sciences 101 (16), 5892-5897, 2004 | 70 | 2004 |
Thermodynamics of oxidation-reduction reactions in mammalian nitric-oxide synthase isoforms YT Gao, SME Smith, JB Weinberg, HJ Montgomery, E Newman, ... Journal of Biological Chemistry 279 (18), 18759-18766, 2004 | 68 | 2004 |