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David Langlais
David Langlais
Associate Professor, McGill University
在 mcgill.ca 的电子邮件经过验证 - 首页
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引用次数
引用次数
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The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation
D Langlais, LB Barreiro, P Gros
Journal of Experimental Medicine 213 (4), 585-603, 2016
2192016
The Stat3/GR interaction code: predictive value of direct/indirect DNA recruitment for transcription outcome
D Langlais, C Couture, A Balsalobre, J Drouin
Molecular cell 47 (1), 38-49, 2012
2002012
Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs
S Berlivet, D Paquette, A Dumouchel, D Langlais, J Dostie, M Kmita
PLoS genetics 9 (12), e1004018, 2013
1992013
Human T-bet governs innate and innate-like adaptive IFN-γ immunity against mycobacteria
R Yang, F Mele, L Worley, D Langlais, J Rosain, I Benhsaien, H Elarabi, ...
Cell 183 (7), 1826-1847. e31, 2020
1072020
Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency
XF Kong, R Martinez-Barricarte, J Kennedy, F Mele, T Lazarov, ...
Nature immunology 19 (9), 973-985, 2018
1012018
USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation
S Torre, MJ Polyak, D Langlais, N Fodil, JM Kennedy, I Radovanovic, ...
Nature immunology 18 (1), 54-63, 2017
962017
Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child
M Ogishi, R Yang, C Aytekin, D Langlais, M Bourgey, T Khan, FA Ali, ...
Nature medicine 27 (9), 1646-1654, 2021
882021
Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis
JF Marquis, O Kapoustina, D Langlais, R Ruddy, CR Dufour, BH Kim, ...
PLoS genetics 7 (6), e1002097, 2011
782011
Distal limb patterning requires modulation of cis-regulatory activities by HOX13
R Sheth, I Barozzi, D Langlais, M Osterwalder, S Nemec, HL Carlson, ...
Cell reports 17 (11), 2913-2926, 2016
762016
Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8K108E mutation
S Salem, D Langlais, F Lefebvre, G Bourque, V Bigley, M Haniffa, ...
Blood, The Journal of the American Society of Hematology 124 (12), 1894-1904, 2014
762014
The Cables1 Gene in Glucocorticoid Regulation of Pituitary Corticotrope Growth and Cushing Disease
A Roussel-Gervais, C Couture, D Langlais, S Takayasu, A Balsalobre, ...
The Journal of Clinical Endocrinology & Metabolism 101 (2), 513-522, 2016
672016
Irf8-Regulated Genomic Responses Drive Pathological Inflammation during Cerebral Malaria
J Berghout, D Langlais, I Radovanovic, M Tam, JD MacMicking, ...
PLoS pathogens 9 (7), e1003491, 2013
652013
Primary immunodeficiencies and inflammatory disease: a growing genetic intersection
N Fodil, D Langlais, P Gros
Trends in immunology 37 (2), 126-140, 2016
642016
p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency
JI Belle, D Langlais, JC Petrov, M Pardo, RG Jones, P Gros, A Nijnik
Blood, The Journal of the American Society of Hematology 125 (15), 2344-2348, 2015
642015
Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy
V Béziat, F Rapaport, J Hu, M Titeux, MB Des Claustres, M Bourgey, ...
Cell 184 (14), 3812-3828. e30, 2021
632021
Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance
JI Belle, JC Petrov, D Langlais, F Robert, R Cencic, S Shen, J Pelletier, ...
Cell Death & Differentiation 23 (5), 759-775, 2016
572016
Transcriptional mechanisms that control expression of the macrophage colony-stimulating factor receptor locus
R Rojo, C Pridans, D Langlais, DA Hume
Clinical science 131 (16), 2161-2182, 2017
542017
CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation
JM Kennedy, N Fodil, S Torre, SE Bongfen, JF Olivier, V Leung, ...
Journal of Experimental Medicine 211 (13), 2519-2535, 2014
542014
A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells
D Langlais, C Couture, G Sylvain-Drolet, J Drouin
Molecular endocrinology 25 (2), 348-359, 2011
512011
Regulatory network analyses reveal genome-wide potentiation of LIF signaling by glucocorticoids and define an innate cell defense response
D Langlais, C Couture, A Balsalobre, J Drouin
PLoS genetics 4 (10), e1000224, 2008
512008
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