The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation D Langlais, LB Barreiro, P Gros Journal of Experimental Medicine 213 (4), 585-603, 2016 | 219 | 2016 |
The Stat3/GR interaction code: predictive value of direct/indirect DNA recruitment for transcription outcome D Langlais, C Couture, A Balsalobre, J Drouin Molecular cell 47 (1), 38-49, 2012 | 200 | 2012 |
Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs S Berlivet, D Paquette, A Dumouchel, D Langlais, J Dostie, M Kmita PLoS genetics 9 (12), e1004018, 2013 | 199 | 2013 |
Human T-bet governs innate and innate-like adaptive IFN-γ immunity against mycobacteria R Yang, F Mele, L Worley, D Langlais, J Rosain, I Benhsaien, H Elarabi, ... Cell 183 (7), 1826-1847. e31, 2020 | 107 | 2020 |
Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency XF Kong, R Martinez-Barricarte, J Kennedy, F Mele, T Lazarov, ... Nature immunology 19 (9), 973-985, 2018 | 101 | 2018 |
USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation S Torre, MJ Polyak, D Langlais, N Fodil, JM Kennedy, I Radovanovic, ... Nature immunology 18 (1), 54-63, 2017 | 96 | 2017 |
Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child M Ogishi, R Yang, C Aytekin, D Langlais, M Bourgey, T Khan, FA Ali, ... Nature medicine 27 (9), 1646-1654, 2021 | 88 | 2021 |
Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis JF Marquis, O Kapoustina, D Langlais, R Ruddy, CR Dufour, BH Kim, ... PLoS genetics 7 (6), e1002097, 2011 | 78 | 2011 |
Distal limb patterning requires modulation of cis-regulatory activities by HOX13 R Sheth, I Barozzi, D Langlais, M Osterwalder, S Nemec, HL Carlson, ... Cell reports 17 (11), 2913-2926, 2016 | 76 | 2016 |
Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8K108E mutation S Salem, D Langlais, F Lefebvre, G Bourque, V Bigley, M Haniffa, ... Blood, The Journal of the American Society of Hematology 124 (12), 1894-1904, 2014 | 76 | 2014 |
The Cables1 Gene in Glucocorticoid Regulation of Pituitary Corticotrope Growth and Cushing Disease A Roussel-Gervais, C Couture, D Langlais, S Takayasu, A Balsalobre, ... The Journal of Clinical Endocrinology & Metabolism 101 (2), 513-522, 2016 | 67 | 2016 |
Irf8-Regulated Genomic Responses Drive Pathological Inflammation during Cerebral Malaria J Berghout, D Langlais, I Radovanovic, M Tam, JD MacMicking, ... PLoS pathogens 9 (7), e1003491, 2013 | 65 | 2013 |
Primary immunodeficiencies and inflammatory disease: a growing genetic intersection N Fodil, D Langlais, P Gros Trends in immunology 37 (2), 126-140, 2016 | 64 | 2016 |
p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency JI Belle, D Langlais, JC Petrov, M Pardo, RG Jones, P Gros, A Nijnik Blood, The Journal of the American Society of Hematology 125 (15), 2344-2348, 2015 | 64 | 2015 |
Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy V Béziat, F Rapaport, J Hu, M Titeux, MB Des Claustres, M Bourgey, ... Cell 184 (14), 3812-3828. e30, 2021 | 63 | 2021 |
Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance JI Belle, JC Petrov, D Langlais, F Robert, R Cencic, S Shen, J Pelletier, ... Cell Death & Differentiation 23 (5), 759-775, 2016 | 57 | 2016 |
Transcriptional mechanisms that control expression of the macrophage colony-stimulating factor receptor locus R Rojo, C Pridans, D Langlais, DA Hume Clinical science 131 (16), 2161-2182, 2017 | 54 | 2017 |
CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation JM Kennedy, N Fodil, S Torre, SE Bongfen, JF Olivier, V Leung, ... Journal of Experimental Medicine 211 (13), 2519-2535, 2014 | 54 | 2014 |
A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells D Langlais, C Couture, G Sylvain-Drolet, J Drouin Molecular endocrinology 25 (2), 348-359, 2011 | 51 | 2011 |
Regulatory network analyses reveal genome-wide potentiation of LIF signaling by glucocorticoids and define an innate cell defense response D Langlais, C Couture, A Balsalobre, J Drouin PLoS genetics 4 (10), e1000224, 2008 | 51 | 2008 |