Do mutations in the murine ataxia gene TRPC3 cause cerebellar ataxia in humans? BL Fogel, SM Hanson, EBE Becker Movement disorders: official journal of the Movement Disorder Society 30 (2 …, 2015 | 100 | 2015 |
Capsaicin interaction with TRPV1 channels in a lipid bilayer: molecular dynamics simulation SM Hanson, S Newstead, KJ Swartz, MSP Sansom Biophysical journal 108 (6), 1425-1434, 2015 | 95 | 2015 |
What makes a kinase promiscuous for inhibitors? SM Hanson, G Georghiou, MK Thakur, WT Miller, JS Rest, JD Chodera, ... Cell chemical biology 26 (3), 390-399. e5, 2019 | 82 | 2019 |
Heat activation is intrinsic to the pore domain of TRPV1 F Zhang, A Jara-Oseguera, TH Chang, C Bae, SM Hanson, KJ Swartz Proceedings of the National Academy of Sciences 115 (2), E317-E324, 2018 | 80 | 2018 |
Reactant stationary approximation in enzyme kinetics SM Hanson, S Schnell The journal of physical chemistry A 112 (37), 8654-8658, 2008 | 73 | 2008 |
A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation EF Ruff, JM Muretta, AR Thompson, EW Lake, S Cyphers, SK Albanese, ... Elife 7, e32766, 2018 | 64 | 2018 |
Engineering vanilloid-sensitivity into the rat TRPV2 channel F Zhang, SM Hanson, A Jara-Oseguera, D Krepkiy, C Bae, LV Pearce, ... Elife 5, e16409, 2016 | 53 | 2016 |
An open library of human kinase domain constructs for automated bacterial expression SK Albanese, DL Parton, M Işık, L Rodríguez-Laureano, SM Hanson, ... Biochemistry 57 (31), 4675-4689, 2018 | 46 | 2018 |
A test for measuring the effects of enzyme inactivation S Schnell, SM Hanson Biophysical chemistry 125 (2-3), 269-274, 2007 | 26 | 2007 |
Ensembler: Enabling high-throughput molecular simulations at the superfamily scale DL Parton, PB Grinaway, SM Hanson, KA Beauchamp, JD Chodera PLoS computational biology 12 (6), e1004728, 2016 | 23 | 2016 |
Modeling error in experimental assays using the bootstrap principle: understanding discrepancies between assays using different dispensing technologies SM Hanson, S Ekins, JD Chodera Journal of computer-aided molecular design 29, 1073-1086, 2015 | 23 | 2015 |
Packing of the extracellular domain hydrophobic core has evolved to facilitate pentameric ligand-gated ion channel function CD Dellisanti, SM Hanson, L Chen, C Czajkowski Journal of Biological Chemistry 286 (5), 3658-3670, 2011 | 22 | 2011 |
Conformational heterogeneity and probability distributions from single-particle cryo-electron microscopy WS Tang, ED Zhong, SM Hanson, EH Thiede, P Cossio Current Opinion in Structural Biology 81, 102626, 2023 | 15 | 2023 |
Ensemble reweighting using cryo-EM particle images WS Tang, D Silva-Sánchez, J Giraldo-Barreto, B Carpenter, SM Hanson, ... The Journal of Physical Chemistry B 127 (24), 5410-5421, 2023 | 13 | 2023 |
Modeling Suggests TRPC3 Hydrogen Bonding and Not Phosphorylation Contributes to the Ataxia Phenotype of the Moonwalker Mouse SM Hanson, MSP Sansom, EBE Becker Biochemistry 54 (26), 4033-4041, 2015 | 10 | 2015 |
Protein dynamics underlying allosteric regulation MA Astore, AS Pradhan, EH Thiede, SM Hanson Current Opinion in Structural Biology 84, 102768, 2024 | 4 | 2024 |
Structure-function analysis suggests that the photoreceptor LITE-1 is a light-activated ion channel SM Hanson, J Scholüke, J Liewald, R Sharma, C Ruse, M Engel, ... Current Biology 33 (16), 3423-3435. e5, 2023 | 4 | 2023 |
Specificity, synergy, and mechanisms of splice-modifying drugs Y Ishigami, MS Wong, C Martí-Gómez, A Ayaz, M Kooshkbaghi, ... Nature Communications 15 (1), 1880, 2024 | 3 | 2024 |
Molecular basis of polyglutamine-modulated ELF3 phase change in Arabidopsis temperature response RJ Lindsay, PA Wigge, SM Hanson BioRxiv, 2023.03. 15.532793, 2023 | 3 | 2023 |
Specificity, synergy, and mechanisms of splice-modifying drugs Y Ishigami, MS Wong, C Martí-Gómez, A Ayaz, M Kooshkbaghi, S Hanson, ... bioRxiv, 2022.12. 30.522303, 2022 | 3 | 2022 |