Interferon pathway in SLE: one key to unlocking the mystery of the disease L Rönnblom, D Leonard Lupus science & medicine 6 (1), e000270, 2019 | 308 | 2019 |
DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus J Imgenberg-Kreuz, JC Almlöf, D Leonard, A Alexsson, G Nordmark, ... Annals of the rheumatic diseases 77 (5), 736-743, 2018 | 145 | 2018 |
A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus LM Olsson, ÅC Johansson, B Gullstrand, A Jönsen, S Saevarsdottir, ... Annals of the rheumatic diseases 76 (9), 1607-1613, 2017 | 122 | 2017 |
IFN-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes is promoted by NK cells via MIP-1β and LFA-1 N Hagberg, O Berggren, D Leonard, G Weber, YT Bryceson, GV Alm, ... The Journal of Immunology 186 (9), 5085-5094, 2011 | 113 | 2011 |
High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus S Reid, A Alexsson, M Frodlund, D Morris, JK Sandling, K Bolin, ... Annals of the rheumatic diseases 79 (3), 363-369, 2020 | 107 | 2020 |
A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus E Svenungsson, J Gustafsson, D Leonard, J Sandling, I Gunnarsson, ... Annals of the rheumatic diseases 69 (5), 834-840, 2010 | 105 | 2010 |
Sex differences in clinical presentation of systemic lupus erythematosus JI Ramírez Sepúlveda, K Bolin, J Mofors, D Leonard, E Svenungsson, ... Biology of sex differences 10, 1-7, 2019 | 99 | 2019 |
The STAT4 SLE risk allele rs7574865 [T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE N Hagberg, M Joelsson, D Leonard, S Reid, ML Eloranta, J Mo, ... Annals of the rheumatic diseases 77 (7), 1070-1077, 2018 | 98 | 2018 |
Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus JC Almlöf, S Nystedt, D Leonard, ML Eloranta, G Grosso, C Sjöwall, ... Human genetics 138, 141-150, 2019 | 76 | 2019 |
HLA-DRB1* 04/* 13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus E Lundström, JT Gustafsson, A Jönsen, D Leonard, A Zickert, K Elvin, ... Annals of the rheumatic diseases 72 (6), 1018-1025, 2013 | 70 | 2013 |
Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus L Odqvist, Z Jevnikar, R Riise, L Öberg, M Rhedin, D Leonard, L Yrlid, ... Annals of the Rheumatic Diseases 78 (10), 1363-1370, 2019 | 69 | 2019 |
Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants D Leonard, E Svenungsson, JK Sandling, O Berggren, A Jönsen, ... Circulation: Cardiovascular Genetics 6 (3), 255-263, 2013 | 61 | 2013 |
Clinical manifestations and anti-phospholipid antibodies in 712 patients with systemic lupus erythematosus: evaluation of two diagnostic assays A Vikerfors, AB Johansson, JT Gustafsson, A Jönsen, D Leonard, ... Rheumatology 52 (3), 501-509, 2013 | 61 | 2013 |
Novel risk genes for systemic lupus erythematosus predicted by random forest classification JC Almlöf, A Alexsson, J Imgenberg-Kreuz, L Sylwan, C Bäcklin, ... Scientific reports 7 (1), 6236, 2017 | 58 | 2017 |
Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis D Leonard, E Svenungsson, J Dahlqvist, A Alexsson, L Ärlestig, KE Taylor, ... Annals of the rheumatic diseases 77 (7), 1063-1069, 2018 | 52 | 2018 |
Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing JK Sandling, P Pucholt, LH Rosenberg, FHG Farias, SV Kozyrev, ... Annals of the rheumatic diseases 80 (1), 109-117, 2021 | 51 | 2021 |
Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes D Leonard, ML Eloranta, N Hagberg, O Berggren, K Tandre, G Alm, ... Annals of the rheumatic diseases 75 (9), 1728-1734, 2016 | 49 | 2016 |
Shared and unique patterns of DNA methylation in systemic lupus erythematosus and primary Sjögren's syndrome J Imgenberg-Kreuz, JC Almlöf, D Leonard, C Sjöwall, AC Syvänen, ... Frontiers in Immunology 10, 1686, 2019 | 47 | 2019 |
The majority of Swedish systemic lupus erythematosus patients are still affected by irreversible organ impairment: factors related to damage accrual in two regional cohorts M Frodlund, S Reid, J Wetterö, Ö Dahlström, C Sjöwall, D Leonard Lupus 28 (10), 1261-1272, 2019 | 43 | 2019 |
Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA‐DRB1 Genotype Associations and Immunological and … LM Diaz‐Gallo, V Oke, E Lundström, K Elvin, Y Ling Wu, S Eketjäll, ... ACR open rheumatology 4 (1), 27-39, 2022 | 42 | 2022 |