| Megahertz serial crystallography MO Wiedorn, D Oberthür, R Bean, R Schubert, N Werner, B Abbey, ... Nature communications 9 (1), 4025, 2018 | 220 | 2018 |
| Aldose reductase structures: implications for mechanism and inhibition O El-Kabbani, F Ruiz, C Darmanin, RPT Chung Cellular and Molecular Life Sciences CMLS 61, 750-762, 2004 | 151 | 2004 |
| Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding … O El‐Kabbani, C Darmanin, TR Schneider, I Hazemann, F Ruiz, M Oka, ... Proteins: Structure, Function, and Bioinformatics 55 (4), 805-813, 2004 | 110 | 2004 |
| Sorbitol dehydrogenase: structure, function and ligand design O El-Kabbani, C Darmanin, RPT Chung Current medicinal chemistry 11 (4), 465-476, 2004 | 100 | 2004 |
| Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity O El-Kabbani, V Carbone, C Darmanin, M Oka, A Mitschler, A Podjarny, ... Journal of medicinal chemistry 48 (17), 5536-5542, 2005 | 83 | 2005 |
| MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography MTB Clabbers, S Holmes, TW Muusse, PR Vajjhala, SJ Thygesen, ... Nature communications 12 (1), 2578, 2021 | 73 | 2021 |
| Hematin− hematin self-association states involved in the formation and reactivity of the malaria parasite pigment, hemozoin N Klonis, R Dilanian, E Hanssen, C Darmanin, V Streltsov, S Deed, ... Biochemistry 49 (31), 6804-6811, 2010 | 69 | 2010 |
| High-throughput production and structural characterization of libraries of self-assembly lipidic cubic phase materials C Darmanin, CE Conn, J Newman, X Mulet, SA Seabrook, YL Liang, ... ACS combinatorial science 14 (4), 247-252, 2012 | 46 | 2012 |
| Incorporation of the dopamine D2L receptor and bacteriorhodopsin within bicontinuous cubic lipid phases. 1. Relevance to in meso crystallization of integral membrane proteins … CE Conn, C Darmanin, SM Sagnella, X Mulet, TL Greaves, JN Varghese, ... Soft Matter 6 (19), 4828-4837, 2010 | 44 | 2010 |
| High-throughput analysis of the structural evolution of the monoolein cubic phase in situ under crystallogenesis conditions CE Conn, C Darmanin, X Mulet, S Le Cann, N Kirby, CJ Drummond Soft Matter 8 (7), 2310-2321, 2012 | 43 | 2012 |
| Incorporation of the dopamine D2L receptor and bacteriorhodopsin within bicontinuous cubic lipid phases. 2. Relevance to in meso crystallization of integral membrane proteins … CE Conn, C Darmanin, SM Sagnella, X Mulet, TL Greaves, JN Varghese, ... Soft Matter 6 (19), 4838-4846, 2010 | 41 | 2010 |
| Structure of human aldose reductase holoenzyme in complex with Statil: An approach to structure‐based inhibitor design of the enzyme O El‐Kabbani, P Ramsland, C Darmanin, RPT Chung, A Podjarny Proteins: Structure, Function, and Bioinformatics 50 (2), 230-238, 2003 | 41 | 2003 |
| Evaluation of serial crystallographic structure determination within megahertz pulse trains O Yefanov, D Oberthür, R Bean, MO Wiedorn, J Knoska, G Pena, S Awel, ... Structural Dynamics 6 (6), 2019 | 38 | 2019 |
| High-resolution structures of human aldose reductase holoenzyme in complex with stereoisomers of the potent inhibitor Fidarestat: stereospecific interaction between the enzyme … O El-Kabbani, C Darmanin, M Oka, C Schulze-Briese, T Tomizaki, ... Journal of medicinal chemistry 47 (18), 4530-4537, 2004 | 36 | 2004 |
| Enhanced uptake of an integral membrane protein, the dopamine D2L receptor, by cubic nanostructured lipid nanoparticles doped with Ni (II) chelated EDTA amphiphiles CE Conn, X Mulet, MJ Moghaddam, C Darmanin, LJ Waddington, ... Soft Matter 7 (2), 567-578, 2011 | 35 | 2011 |
| Effect of lipid architecture on cubic phase susceptibility to crystallisation screens CE Conn, C Darmanin, X Mulet, A Hawley, CJ Drummond Soft Matter 8 (26), 6884-6896, 2012 | 33 | 2012 |
| In meso crystallization: compatibility of different lipid bicontinuous cubic mesophases with the cubic crystallization screen in aqueous solution L van’t Hag, C Darmanin, TC Le, S Mudie, CE Conn, CJ Drummond Crystal growth & design 14 (4), 1771-1781, 2014 | 31 | 2014 |
| Protein crystal screening and characterization for serial femtosecond nanocrystallography C Darmanin, J Strachan, CG Adda, T Ve, B Kobe, B Abbey Scientific reports 6 (1), 25345, 2016 | 30 | 2016 |
| Crystal structure of human L‐xylulose reductase holoenzyme: Probing the role of Asn107 with site‐directed mutagenesis O El‐Kabbani, S Ishikura, C Darmanin, V Carbone, RPT Chung, N Usami, ... Proteins: Structure, Function, and Bioinformatics 55 (3), 724-732, 2004 | 30 | 2004 |
| Lysozyme conformational changes with ionic liquids: Spectroscopic, small angle x-ray scattering and crystallographic study Q Han, KM Smith, C Darmanin, TM Ryan, CJ Drummond, TL Greaves Journal of Colloid and Interface Science 585, 433-443, 2021 | 29 | 2021 |
