Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria V Feuillet, S Medjane, I Mondor, O Demaria, PP Pagni, JE Galán, ... Proceedings of the National Academy of Sciences 103 (33), 12487-12492, 2006 | 410 | 2006 |
TLR8 deficiency leads to autoimmunity in mice Demaria O, Pagni PP, Traub S, de Gassart A, Branzk N, Murphy AJ, Valenzuela ... J Clin Invest., 2010 | 224 | 2010 |
Anti-IL-21 monoclonal antibody combined with liraglutide effectively reverses established hyperglycemia in mouse models of type 1 diabetes AK Rydén, NR Perdue, PP Pagni, CB Gibson, SS Ratliff, RK Kirk, ... Journal of autoimmunity 84, 65-74, 2017 | 42 | 2017 |
Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: immunologic effects and efficacy in NOD mice G Sarikonda, S Sachithanantham, Y Manenkova, T Kupfer, A Posgai, ... PloS one 8 (2), e54712, 2013 | 42 | 2013 |
Contribution of TLR7 and TLR9 signaling to the susceptibility of MyD88-deficient mice to myocarditis PP Pagni, S Traub, O Demaria, L Chasson, L Alexopoulou Autoimmunity 43 (4), 275-287, 2010 | 41 | 2010 |
A preclinical consortium approach for assessing the efficacy of combined anti-CD3 plus IL-1 blockade in reversing new-onset autoimmune diabetes in NOD mice RG Gill, PP Pagni, T Kupfer, CH Wasserfall, S Deng, A Posgai, ... Diabetes 65 (5), 1310-1316, 2016 | 40 | 2016 |
The clinical and immunological significance of GAD-specific autoantibody and T-cell responses in type 1 diabetes T Boettler, PP Pagni, R Jaffe, Y Cheng, P Zerhouni, M von Herrath Journal of autoimmunity 44, 40-48, 2013 | 39 | 2013 |
Male microchimerism and HLA compatibility in French women with sclerodema: a different profile in limited and diffuse subset JM Rak, PP Pagni, K Tiev, Y Allanore, D Farge, JR Harle, D Launay, ... Rheumatology 48 (4), 363-366, 2009 | 38 | 2009 |
Functional redundancy of CXCR3/CXCL10 signaling in the recruitment of diabetogenic cytotoxic T lymphocytes to pancreatic islets in a virally induced autoimmune diabetes model KT Coppieters, N Amirian, PP Pagni, C Baca Jones, A Wiberg, S Lasch, ... Diabetes 62 (7), 2492-2499, 2013 | 33 | 2013 |
Following the fate of one insulin-reactive CD4 T cell: conversion into Teffs and Tregs in the periphery controls diabetes in NOD mice G Fousteri, J Jasinski, A Dave, M Nakayama, P Pagni, F Lambolez, ... Diabetes 61 (5), 1169-1179, 2012 | 32 | 2012 |
Case reports of pre-clinical replication studies in metabolism and diabetes M von Herrath, PP Pagni, K Grove, G Christoffersson, ... Cell Metabolism 29 (4), 795-802, 2019 | 31 | 2019 |
Comparing HLA shared epitopes in French Caucasian patients with scleroderma LNC Azzouz DF, Rak JM, Fajardy I, Allanore Y, Tiev KP, Farge-Bancel D ... PLoS One, 2012 | 27 | 2012 |
Combination therapy with an anti–IL-1β antibody and GAD65 DNA vaccine can reverse recent-onset diabetes in the RIP-GP mouse model PP Pagni, D Bresson, T Rodriguez-Calvo, A Bel Hani, Y Manenkova, ... Diabetes 63 (6), 2015-2025, 2014 | 22 | 2014 |
Oral insulin (human, murine, or porcine) does not prevent diabetes in the non-obese diabetic mouse MN Pham, C Gibson, AKE Rydén, N Perdue, TE Boursalian, PP Pagni, ... Clinical immunology 164, 28-33, 2016 | 21 | 2016 |
Regulatory T cells control diabetes without compromising acute anti-viral defense CB Jones, PP Pagni, G Fousteri, S Sachithanantham, A Dave, ... Clinical Immunology 153 (2), 298-307, 2014 | 17 | 2014 |
Beta-cell specific production of IL6 in conjunction with a mainly intracellular but not mainly surface viral protein causes diabetes TL Van Belle, PP Pagni, J Liao, S Sachithanantham, A Dave, AB Hani, ... Journal of autoimmunity 55, 24-32, 2014 | 14 | 2014 |
Multicomponent plasmid protects mice from spontaneous autoimmune diabetes PP Pagni, J Chaplin, M Wijaranakula, JD Wesley, J Granger, J Cracraft, ... Diabetes 71 (1), 157-169, 2022 | 13 | 2022 |
The Hsp60 peptide p277 enhances anti-CD3 mediated diabetes remission in non-obese diabetic mice G Sarikonda, S Sachithanantham, JF Miller, PP Pagni, KT Coppieters, ... Journal of Autoimmunity 59, 61-66, 2015 | 10 | 2015 |
Metabolically inactive insulin analogue does not prevent autoimmune diabetes in NOD mice J Grönholm, PP Pagni, MN Pham, CB Gibson, PF Macomber, JL Vela, ... Diabetologia 60, 1475-1482, 2017 | 8 | 2017 |
CD40-targeted peptide proposed for type 1 diabetes therapy lacks relevant binding affinity to its cognate receptor PP Pagni, A Wolf, M Lo Conte, R Yeh, G Fu, F Liu, M von Herrath, ... Diabetologia 62, 1727-1729, 2019 | 4 | 2019 |