Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis K Shimada, TR Crother, J Karlin, J Dagvadorj, N Chiba, S Chen, ... Immunity 36 (3), 401-414, 2012 | 2062 | 2012 |
Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E KS Michelsen, MH Wong, PK Shah, W Zhang, J Yano, TM Doherty, ... Proceedings of the National Academy of Sciences 101 (29), 10679-10684, 2004 | 1262 | 2004 |
Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to … MT Abreu, P Vora, E Faure, LS Thomas, ET Arnold, M Arditi The Journal of Immunology 167 (3), 1609-1616, 2001 | 952 | 2001 |
Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL XH Xu, PK Shah, E Faure, O Equils, L Thomas, MC Fishbein, D Luthringer, ... Circulation 104 (25), 3103-3108, 2001 | 896 | 2001 |
TLR signaling in the gut in health and disease MT Abreu, M Fukata, M Arditi The Journal of Immunology 174 (8), 4453-4460, 2005 | 842 | 2005 |
Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes FX Zhang, CJ Kirschning, R Mancinelli, XP Xu, Y Jin, E Faure, ... Journal of Biological Chemistry 274 (12), 7611-7614, 1999 | 773 | 1999 |
Bacterial lipopolysaccharide activates NF-κB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells: differential expression of TLR-4 and TLR-2 in … E Faure, O Equils, PA Sieling, L Thomas, FX Zhang, CJ Kirschning, ... Journal of Biological Chemistry 275 (15), 11058-11063, 2000 | 741 | 2000 |
Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis M Fukata, KS Michelsen, R Eri, LS Thomas, B Hu, K Lukasek, CC Nast, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 288 (5 …, 2005 | 634 | 2005 |
Bacterial lipopolysaccharide and IFN-γ induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-κB activation E Faure, L Thomas, H Xu, AE Medvedev, O Equils, M Arditi The Journal of Immunology 166 (3), 2018-2024, 2001 | 591 | 2001 |
Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut G Melmed, LS Thomas, N Lee, SY Tesfay, K Lukasek, KS Michelsen, ... The Journal of Immunology 170 (3), 1406-1415, 2003 | 578 | 2003 |
Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway Y Bulut, E Faure, L Thomas, H Karahashi, KS Michelsen, O Equils, ... The Journal of immunology 168 (3), 1435-1440, 2002 | 564 | 2002 |
Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine M Fukata, A Chen, A Klepper, S Krishnareddy, AS Vamadevan, ... Gastroenterology 131 (3), 862-877, 2006 | 516 | 2006 |
TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells MT Abreu, ET Arnold, LS Thomas, R Gonsky, Y Zhou, B Hu, M Arditi Journal of Biological Chemistry 277 (23), 20431-20437, 2002 | 505 | 2002 |
Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll … Y Bulut, E Faure, L Thomas, O Equils, M Arditi The Journal of immunology 167 (2), 987-994, 2001 | 504 | 2001 |
Hexokinase is an innate immune receptor for the detection of bacterial peptidoglycan AJ Wolf, CN Reyes, W Liang, C Becker, K Shimada, ML Wheeler, HC Cho, ... Cell 166 (3), 624-636, 2016 | 499 | 2016 |
β-defensin-2 expression is regulated by TLR signaling in intestinal epithelial cells P Vora, A Youdim, LS Thomas, M Fukata, SY Tesfay, K Lukasek, ... The Journal of Immunology 173 (9), 5398-5405, 2004 | 489 | 2004 |
The roles of bacteria and TLR4 in rat and murine models of necrotizing enterocolitis T Jilling, D Simon, J Lu, FJ Meng, D Li, R Schy, RB Thomson, A Soliman, ... The Journal of Immunology 177 (5), 3273-3282, 2006 | 440 | 2006 |
Three-year multicenter surveillance of pneumococcal meningitis in children: clinical characteristics, and outcome related to penicillin susceptibility and dexamethasone use M Arditi, EO Mason Jr, JS Bradley, TQ Tan, WJ Barson, GE Schutze, ... Pediatrics 102 (5), 1087-1097, 1998 | 424 | 1998 |
HMGB1 mediates endogenous TLR2 activation and brain tumor regression JF Curtin, N Liu, M Candolfi, W Xiong, H Assi, K Yagiz, MR Edwards, ... PLoS medicine 6 (1), e1000010, 2009 | 401 | 2009 |
Immunological consequences of intestinal fungal dysbiosis ML Wheeler, JJ Limon, AS Bar, CA Leal, M Gargus, J Tang, J Brown, ... Cell host & microbe 19 (6), 865-873, 2016 | 390 | 2016 |