CDK4/6 inhibition triggers anti-tumour immunity S Goel, MJ DeCristo, AC Watt, H BrinJones, J Sceneay, BB Li, N Khan, ... Nature 548 (7668), 471-475, 2017 | 1240 | 2017 |
Overcoming therapeutic resistance in HER2-positive breast cancers with CDK4/6 inhibitors S Goel, Q Wang, AC Watt, SM Tolaney, DA Dillon, W Li, S Ramm, ... Cancer cell 29 (3), 255-269, 2016 | 446 | 2016 |
A quantitative approach to screen for nephrotoxic compounds in vitro M Adler, S Ramm, M Hafner, JL Muhlich, EM Gottwald, E Weber, A Jaklic, ... Journal of the American Society of Nephrology 27 (4), 1015-1028, 2016 | 133 | 2016 |
Human kidney on a chip assessment of polymyxin antibiotic nephrotoxicity EJ Weber, KA Lidberg, L Wang, TK Bammler, JW MacDonald, MJ Li, ... JCI insight 3 (24), 2018 | 78 | 2018 |
Role of drug-independent stress factors in liver injury associated with diclofenac intake S Ramm, A Mally Toxicology 312, 83-96, 2013 | 47 | 2013 |
High-throughput imaging assay for drug screening of 3D prostate cancer organoids N Choo, S Ramm, J Luu, JM Winter, LA Selth, AR Dwyer, M Frydenberg, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (9), 1107-1124, 2021 | 42 | 2021 |
A thiol‐bound drug reservoir enhances APR‐246‐induced mutant p53 tumor cell death S Ceder, SE Eriksson, EH Cheteh, S Dawar, M Corrales Benitez, ... EMBO molecular medicine 13 (2), e10852, 2021 | 39 | 2021 |
CX-5461 sensitizes DNA damage repair–proficient castrate-resistant prostate cancer to PARP inhibition MG Lawrence, LH Porter, N Choo, D Pook, JP Grummet, CJ Pezaro, ... Molecular cancer therapeutics 20 (11), 2140-2150, 2021 | 17 | 2021 |
A high‐throughput screening assay to identify kidney toxic compounds S Ramm, M Adler, VS Vaidya Current protocols in toxicology 69 (1), 9.10. 1-9.10. 26, 2016 | 17 | 2016 |
A Systems Toxicology Approach for the Prediction of Kidney Toxicity and Its Mechanisms In Vitro S Ramm, P Todorov, V Chandrasekaran, A Dohlman, MB Monteiro, ... Toxicological Sciences 169 (1), 54-69, 2019 | 16 | 2019 |
INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors C Dietrich, A Trub, A Ahn, M Taylor, K Ambani, KT Chan, KH Lu, ... Cancer discovery 14 (3), 446-467, 2024 | 15 | 2024 |
Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease KA Lidberg, AJ Annalora, M Jozic, DJ Elson, L Wang, TK Bammler, ... Scientific reports 11 (1), 4722, 2021 | 14 | 2021 |
Functional and cellular consequences of covalent target protein modification by furan in rat liver S Ramm, E Limbeck, A Mally Toxicology 361, 49-61, 2016 | 13 | 2016 |
Application of a discovery to targeted LC–MS proteomics approach to identify deregulated proteins associated with idiosyncratic liver toxicity in a rat model of LPS/diclofenac … S Ramm, B Morissey, B Hernandez, C Rooney, SR Pennington, A Mally Toxicology 331, 100-111, 2015 | 12 | 2015 |
Occurrence of 2, 2, 4-trimethyl–1, 3-pentanediol monoisobutyrate (Texanol®) in foods packed in polystyrene and polypropylene cups M Kempf, S Ramm, T Feuerbach, P Schreier Food Additives and Contaminants 26 (4), 563-567, 2009 | 12 | 2009 |
A High-Throughput screen identifies DYRK1A inhibitor ID-8 that stimulates human kidney tubular epithelial cell proliferation MB Monteiro, S Ramm, V Chandrasekaran, SA Boswell, EJ Weber, ... Journal of the American Society of Nephrology 29 (12), 2820-2833, 2018 | 8 | 2018 |
High-throughput live and fixed cell imaging method to screen Matrigel-embedded organoids S Ramm, R Vary, T Gulati, J Luu, KJ Cowley, MS Janes, N Radio, ... Organoids 2 (1), 1-19, 2022 | 6 | 2022 |
Targeting of TP53-independent cell cycle checkpoints overcomes FOLFOX resistance in Metastatic Colorectal Cancer C Behrenbruch, M Foroutan, P Lind, J Smith, M Grandin, B Cooper, ... BioRxiv, 2021.02. 04.429849, 2021 | 6 | 2021 |
Radiation therapy attenuates lymphatic vessel repair by reducing VEGFR-3 signalling V Pillay, L Shukla, P Herle, S Maciburko, N Bandara, I Reid, S Morgan, ... Frontiers in Pharmacology 14, 1152314, 2023 | 3 | 2023 |
A quantitative approach to screen for kidney toxic compounds in vitro M Adler, S Ramm, M Hafner, JL Muhlich, E Maria, EW Gottwald, A Jaklic, ... J. Am. Soc. Nephrol, 2015 | 3 | 2015 |