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Patrick Dennler
Patrick Dennler
PhD Student, Center for Radiopharmaceutical Sciences ETHZ-PSI-USZ
在 psi.ch 的电子邮件经过验证
标题
引用次数
引用次数
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Transglutaminase-based chemo-enzymatic conjugation approach yields homogeneous antibody–drug conjugates
P Dennler, A Chiotellis, E Fischer, D Brégeon, C Belmant, L Gauthier, ...
Bioconjugate chemistry 25 (3), 569-578, 2014
3032014
Antibody conjugates: from heterogeneous populations to defined reagents
P Dennler, E Fischer, R Schibli
Antibodies 4 (3), 197-224, 2015
1192015
Site-specific conjugation of monomethyl auristatin E to anti-CD30 antibodies improves their pharmacokinetics and therapeutic index in rodent models
F Lhospice, D Brégeon, C Belmant, P Dennler, A Chiotellis, E Fischer, ...
Molecular pharmaceutics 12 (6), 1863-1871, 2015
1182015
Enzymatic conjugation of polypeptides
D Bregeon, P Dennler, C Belmant, E Fischer, L Gauthier, F Romagné, ...
US Patent 9,717,803, 2017
512017
DOTA-functionalized polylysine: a high number of DOTA chelates positively influences the biodistribution of enzymatic conjugated anti-tumor antibody chCE7agl
J Grünberg, S Jeger, D Sarko, P Dennler, K Zimmermann, W Mier, ...
PLoS One 8 (4), e60350, 2013
482013
Enzymatic conjugation of antibodies
P Dennler, D Bregeon, L Gauthier, F Romagné, C Belmant, E Fischer, ...
US Patent 9,764,038, 2017
302017
Microbial Transglutaminase and c‐myc‐Tag: A Strong Couple for the Functionalization of Antibody‐Like Protein Scaffolds from Discovery Platforms
P Dennler, LK Bailey, PR Spycher, R Schibli, E Fischer
ChemBioChem 16 (5), 861-867, 2015
302015
Enzymatic antibody modification by bacterial transglutaminase
P Dennler, R Schibli, E Fischer
Antibody-drug conjugates, 205-215, 2013
222013
Genomics drugs in clinical trials
J Hall, P Dennler, S Haller, A Pratsinis, K Säuberli, H Towbin, K Walther, ...
Nature reviews drug discovery 9 (12), 988-988, 2010
222010
Preclinical imaging of the co-stimulatory molecules CD80 and CD86 with indium-111-labeled belatacept in atherosclerosis
R Meletta, A Müller Herde, P Dennler, E Fischer, R Schibli, SD Krämer
EJNMMI research 6, 1-12, 2016
212016
Synthesis, radiolabelling and in vitro and in vivo evaluation of a novel fluorinated ABP688 derivative for the PET imaging of metabotropic glutamate receptor subtype 5
SM Sephton, P Dennler, DS Leutwiler, L Mu, CA Wanger-Baumann, ...
American Journal of Nuclear Medicine and Molecular Imaging 2 (1), 14, 2012
212012
Development of [18F]-PSS223 as a PET tracer for imaging of metabotropic glutamate receptor subtype 5 (mGluR5)
SM Sephton, P Dennler, DS Leutwiler, L Mu, R Schibli, SD Krämer, ...
Chimia 66 (4), 201-201, 2012
142012
Recognition tags for TGase-mediated conjugation
E Fischer, F Romagne, P Dennler
US Patent 10,036,010, 2018
122018
Screening of conjugated antibodies
C Belmant, D Bregeon, P Dennler, E Fischer, F Romagne, R Schibli, ...
US Patent 10,132,799, 2018
112018
Enzymatic conjugation of polypeptides
D Bregeon, P Dennler, C Belmant, L Gauthier, F Romagne, E Fischer, ...
US Patent 10,434,180, 2019
92019
Enzymatic conjugation of polypeptides
D Bregeon, P Dennler, C Belmant, E Fischer, L Gauthier, F Romagné, ...
US Patent App. 15/654,585, 2018
52018
Enzymatic conjugation of antibodies
P Dennler, D Bregeon, L Gauthier, F Romagné, C Belmant, E Fischer, ...
US Patent 10,675,359, 2020
32020
Recognition tags for tgase-mediated conjugation
E Fischer, F Romagne, P Dennler
US Patent App. 16/035,437, 2019
22019
Towards homogenous adcs: A new site-specific antibody conjugation using bacterial transglutaminase (btg-adc)
F Lhospice, D Bregeon, C Belmant, A Represa, A Boedec, Y Morel, ...
Cancer Research 74 (19_Supplement), 2514-2514, 2014
12014
Imaging atherosclerotic plaque inflammation with the CD80/CD86-specific In-111-DOTA-Belatacept
R Meletta, AM Herde, P Dennler, E Fischer, SD Kraemer, R Schibli
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 58, S346-S346, 2015
2015
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