Discovery of novel flavonoid dimers to reverse multidrug resistance protein 1 (MRP1, ABCC1) mediated drug resistance in cancers using a high throughput platform with “click … ILK Wong, X Zhu, KF Chan, MC Law, AMY Lo, X Hu, LMC Chow, TH Chan Journal of Medicinal Chemistry 61 (22), 9931-9951, 2018 | 37 | 2018 |
Triazole bridged flavonoid dimers as potent, nontoxic, and highly selective breast cancer resistance protein (BCRP/ABCG2) inhibitors X Zhu, ILK Wong, KF Chan, J Cui, MC Law, TC Chong, X Hu, LMC Chow, ... Journal of medicinal chemistry 62 (18), 8578-8608, 2019 | 36 | 2019 |
Flavonoid dimers are highly potent killers of multidrug resistant cancer cells overexpressing MRP1 L Dury, R Nasr, D Lorendeau, E Comsa, I Wong, X Zhu, KF Chan, ... Biochemical Pharmacology 124, 10-18, 2017 | 36 | 2017 |
Flavonoid monomers as potent, nontoxic, and selective modulators of the breast cancer resistance protein (ABCG2) ILK Wong, X Zhu, KF Chan, Z Liu, CF Chan, TS Chow, TC Chong, ... Journal of medicinal chemistry 64 (19), 14311-14331, 2021 | 13 | 2021 |
Characterization of a Potent, Selective, and Safe Inhibitor, Ac15(Az8)2, in Reversing Multidrug Resistance Mediated by Breast Cancer Resistance Protein (BCRP … TC Chong, ILK Wong, J Cui, MC Law, X Zhu, X Hu, JWY Kan, CSW Yan, ... International Journal of Molecular Sciences 23 (21), 13261, 2022 | 5 | 2022 |
Chemical modulation of multidrug resistant proteins by triazole bridged flavonoid dimers X Zhu Hong Kong Polytechnic University, 2019 | | 2019 |