Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma W Zhang, N Nandakumar, Y Shi, M Manzano, A Smith, G Graham, ... Science signaling 7 (324), ra42-ra42, 2014 | 389 | 2014 |
Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma S Murakami, D Shahbazian, R Surana, W Zhang, H Chen, GT Graham, ... Oncogene 36 (9), 1232-1244, 2017 | 194 | 2017 |
Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors ND Anderson, R de Borja, MD Young, F Fuligni, A Rosic, ND Roberts, ... Science 361 (6405), eaam8419, 2018 | 150 | 2018 |
Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing SP Selvanathan, GT Graham, HV Erkizan, U Dirksen, TG Natarajan, ... Proceedings of the National Academy of Sciences 112 (11), E1307-E1316, 2015 | 144 | 2015 |
The mitochondrial citrate carrier, SLC25A1, drives stemness and therapy resistance in non-small cell lung cancer HR Fernandez, SM Gadre, M Tan, GT Graham, R Mosaoa, MS Ongkeko, ... Cell Death & Differentiation 25 (7), 1239-1258, 2018 | 97 | 2018 |
Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH M Tan, R Mosaoa, GT Graham, A Kasprzyk-Pawelec, S Gadre, E Parasido, ... Cell Death & Differentiation 27 (7), 2143-2157, 2020 | 81 | 2020 |
Inhibition of the oncogenic fusion protein EWS-FLI1 causes G2-M cell cycle arrest and enhanced vincristine sensitivity in Ewing’s sarcoma SK Zöllner, SP Selvanathan, GT Graham, RMT Commins, SH Hong, ... Science signaling 10 (499), eaam8429, 2017 | 65 | 2017 |
A Yap-Myc-Sox2-p53 regulatory network dictates metabolic homeostasis and differentiation in Kras-driven pancreatic ductal adenocarcinomas S Murakami, I Nemazanyy, SM White, H Chen, CDK Nguyen, GT Graham, ... Developmental cell 51 (1), 113-128. e9, 2019 | 56 | 2019 |
A mechanism of resistance to antibody-targeted immune attack DS Aldeghaither, DJ Zahavi, JC Murray, EJ Fertig, GT Graham, YW Zhang, ... Cancer immunology research 7 (2), 230-243, 2019 | 53 | 2019 |
Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer EE Vietsch, GT Graham, JN McCutcheon, A Javaid, G Giaccone, ... Cancer genetics 218, 39-50, 2017 | 51 | 2017 |
The sustained induction of c-MYC drives nab-paclitaxel resistance in primary pancreatic ductal carcinoma cells E Parasido, GS Avetian, A Naeem, G Graham, M Pishvaian, E Glasgow, ... Molecular Cancer Research 17 (9), 1815-1827, 2019 | 50 | 2019 |
Ezrin inhibition up-regulates stress response gene expression H Çelik, G Bulut, J Han, GT Graham, TZ Minas, EJ Conn, SH Hong, ... Journal of Biological Chemistry 291 (25), 13257-13270, 2016 | 50 | 2016 |
EWS–FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex SP Selvanathan, GT Graham, AR Grego, TM Baker, JR Hogg, M Simpson, ... Nucleic acids research 47 (18), 9619-9636, 2019 | 49 | 2019 |
Alterations in cell motility, proliferation, and metabolism in novel models of acquired temozolomide resistant glioblastoma DM Tiek, JD Rone, GT Graham, EL Pannkuk, BR Haddad, RB Riggins Scientific reports 8 (1), 7222, 2018 | 48 | 2018 |
The ETS inhibitors YK-4-279 and TK-216 are novel antilymphoma agents F Spriano, EYL Chung, E Gaudio, C Tarantelli, L Cascione, S Napoli, ... Clinical Cancer Research 25 (16), 5167-5176, 2019 | 44 | 2019 |
RNA helicase A activity is inhibited by oncogenic transcription factor EWS-FLI1 HV Erkizan, JA Schneider, K Sajwan, GT Graham, B Griffin, ... Nucleic acids research 43 (2), 1069-1080, 2015 | 41 | 2015 |
Rac1-mediated DNA damage and inflammation promote Nf2 tumorigenesis but also limit cell-cycle progression Y Shi, SR Bollam, SM White, SZ Laughlin, GT Graham, M Wadhwa, ... Developmental cell 39 (4), 452-465, 2016 | 32 | 2016 |
PBX1 Is a Favorable Prognostic Biomarker as It Modulates 13-cis Retinoic Acid–Mediated Differentiation in Neuroblastoma N Shah, J Wang, J Selich-Anderson, G Graham, H Siddiqui, X Li, J Khan, ... Clinical Cancer Research 20 (16), 4400-4412, 2014 | 26 | 2014 |
Multifactorial analysis of conditional reprogramming of human keratinocytes SB Ligaba, A Khurana, G Graham, E Krawczyk, S Jablonski, EF Petricoin, ... PLoS One 10 (2), e0116755, 2015 | 23 | 2015 |
Loss of ANCO1 repression at AIB1/YAP targets drives breast cancer progression MH Kushner, V Ory, GT Graham, GM Sharif, WB Kietzman, S Thevissen, ... EMBO reports 21 (1), e48741, 2020 | 20 | 2020 |