Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion T Delong, TA Wiles, RL Baker, B Bradley, G Barbour, R Reisdorph, ... Science 351 (6274), 711-714, 2016 | 878* | 2016 |
Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease JA Tye-Din, JA Stewart, JA Dromey, T Beissbarth, DA van Heel, A Tatham, ... Science translational medicine 2 (41), 41ra51-41ra51, 2010 | 528 | 2010 |
Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status D Mittag, AI Proietto, T Loudovaris, SI Mannering, D Vremec, K Shortman, ... The Journal of Immunology 186 (11), 6207-6217, 2011 | 299 | 2011 |
Isolation and preservation of peripheral blood mononuclear cells for analysis of islet antigen-reactive T cell responses: position statement of the T-Cell Workshop Committee of … R Mallone, SI Mannering, BM Brooks-Worrell, I Durinovic-Bello, CM Cilio, ... Clinical & Experimental Immunology 163 (1), 33-49, 2011 | 280 | 2011 |
The insulin A-chain epitope recognized by human T cells is posttranslationally modified SI Mannering, LC Harrison, NA Williamson, JS Morris, DJ Thearle, ... The Journal of experimental medicine 202 (9), 1191-1197, 2005 | 248 | 2005 |
Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time MR Jenkins, JA Rudd-Schmidt, JA Lopez, KM Ramsbottom, SI Mannering, ... Journal of Experimental Medicine 212 (3), 307-317, 2015 | 242 | 2015 |
Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity M Koutsakos, AK Wheatley, L Loh, EB Clemens, S Sant, S Nüssing, A Fox, ... Science translational medicine 10 (428), eaan8405, 2018 | 234 | 2018 |
A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease KN Henderson, JA Tye-Din, HH Reid, Z Chen, NA Borg, T Beissbarth, ... Immunity 27 (1), 23-34, 2007 | 227 | 2007 |
A sensitive method for detecting proliferation of rare autoantigen-specific human T cells SI Mannering, JS Morris, KP Jensen, AW Purcell, MC Honeyman, ... Journal of immunological methods 283 (1-2), 173-183, 2003 | 209 | 2003 |
Human CD8+ T cell cross-reactivity across influenza A, B and C viruses M Koutsakos, PT Illing, THO Nguyen, NA Mifsud, JC Crawford, S Rizzetto, ... Nature immunology 20 (5), 613-625, 2019 | 208 | 2019 |
Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles A Pizzolla, THO Nguyen, S Sant, J Jaffar, T Loudovaris, SI Mannering, ... The Journal of clinical investigation 128 (2), 721-733, 2018 | 181 | 2018 |
Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer–restricted CD4+ T cells infiltrate islets in type 1 diabetes V Pathiraja, JP Kuehlich, PD Campbell, B Krishnamurthy, T Loudovaris, ... Diabetes 64 (1), 172-182, 2015 | 166 | 2015 |
Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease SE Broughton, J Petersen, A Theodossis, SW Scally, KL Loh, ... Immunity 37 (4), 611-621, 2012 | 143 | 2012 |
A type 1 diabetes genetic risk score predicts progression of islet autoimmunity and development of type 1 diabetes in individuals at risk MJ Redondo, S Geyer, AK Steck, S Sharp, JM Wentworth, MN Weedon, ... Diabetes care 41 (9), 1887-1894, 2018 | 137 | 2018 |
HLA-DR1–Restricted bcr-abl (b3a2)-Specific CD4+ T Lymphocytes Respond to Dendritic Cells Pulsed With b3a2 Peptide and Antigen-Presenting Cells Exposed to … SI Mannering, JL McKenzie, DB Fearnley, DNJ Hart Blood, The Journal of the American Society of Hematology 90 (1), 290-297, 1997 | 129 | 1997 |
Isolation of human blood dendritic cells using the CMRF-44 monoclonal antibody: implications for studies on antigen-presenting cell function and immunotherapy DB Fearnley, AD McLellan, SI Mannering, BD Hock, DNJ Hart Blood, The Journal of the American Society of Hematology 89 (10), 3708-3716, 1997 | 128 | 1997 |
Rapid and unidirectional perforin pore delivery at the cytotoxic immune synapse JA Lopez, MR Jenkins, JA Rudd-Schmidt, AJ Brennan, JC Danne, ... The Journal of Immunology 191 (5), 2328-2334, 2013 | 103 | 2013 |
Repurposed JAK1/JAK2 inhibitor reverses established autoimmune insulitis in NOD mice PM Trivedi, KL Graham, NA Scott, MR Jenkins, S Majaw, RM Sutherland, ... Diabetes 66 (6), 1650-1660, 2017 | 91 | 2017 |
Pathogenic mechanisms in type 1 diabetes: the islet is both target and driver of disease KL Graham, RM Sutherland, SI Mannering, Y Zhao, J Chee, ... The review of diabetic studies: RDS 9 (4), 148, 2012 | 87 | 2012 |
Ara h 1 CD4+ T cell epitope‐based peptides: candidates for a peanut allergy therapeutic SR Prickett, AL Voskamp, T Phan, A Dacumos‐Hill, SI Mannering, ... Clinical & Experimental Allergy 43 (6), 684-697, 2013 | 77 | 2013 |