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Arne Bruyneel
Arne Bruyneel
Grunenthal
在 grunenthal.com 的电子邮件经过验证 - 首页
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Metabolic maturation media improve physiological function of human iPSC-derived cardiomyocytes
DAM Feyen, WL McKeithan, AAN Bruyneel, S Spiering, L Hörmann, ...
Cell reports 32 (3), 2020
2762020
An automated platform for assessment of congenital and drug-induced arrhythmia with hiPSC-derived cardiomyocytes
WL McKeithan, A Savchenko, MS Yu, F Cerignoli, AAN Bruyneel, JH Price, ...
Frontiers in physiology 8, 766, 2017
812017
Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ
C Hurtado, A Safarova, M Smith, R Chung, AAN Bruyneel, ...
Scientific reports 9 (1), 10811, 2019
502019
Ambiguity in the presentation of decellularized tissue composition: the need for standardized approaches
AAN Bruyneel, CA Carr
Artificial organs 41 (8), 778-784, 2017
482017
Reengineering an antiarrhythmic drug using patient hiPSC cardiomyocytes to improve therapeutic potential and reduce toxicity
WL McKeithan, DAM Feyen, AAN Bruyneel, KJ Okolotowicz, DA Ryan, ...
Cell Stem Cell 27 (5), 813-821. e6, 2020
432020
Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy
I Perea-Gil, T Seeger, AAN Bruyneel, V Termglinchan, E Monte, EW Lim, ...
European Heart Journal 43 (36), 3477-3489, 2022
372022
Stem cell therapy for the heart: blind alley or magic bullet?
AAN Bruyneel, A Sehgal, S Malandraki-Miller, C Carr
Journal of Cardiovascular Translational Research 9, 405-418, 2016
332016
Bio-mechanical properties of novel bi-layer collagen-elastin scaffolds for heart valve tissue engineering
Q Chen, A Bruyneel, C Carr, J Czernuszka
Procedia Engineering 59, 247-254, 2013
322013
Physiological and pharmacological stimulation for in vitro maturation of substrate metabolism in human induced pluripotent stem cell-derived cardiomyocytes
CA Lopez, HHAA Al-Siddiqi, U Purnama, S Iftekhar, AAN Bruyneel, M Kerr, ...
Scientific reports 11 (1), 7802, 2021
302021
Collagen type I and hyaluronic acid based hybrid scaffolds for heart valve tissue engineering
R Nazir, A Bruyneel, C Carr, J Czernuszka
Biopolymers 110 (8), e23278, 2019
302019
Collagen-based scaffolds for potential application of heart valve tissue engineering
Q Chen, A Bruyneel, K Clarke, C Carr, J Czernuszka
J. Tissue Sci. Eng 11 (003), 1-6, 2012
292012
Will iPSC-cardiomyocytes revolutionize the discovery of drugs for heart disease?
AAN Bruyneel, WL McKeithan, DAM Feyen, M Mercola
Current opinion in pharmacology 42, 55-61, 2018
252018
Mechanical and degradation properties of hybrid scaffolds for tissue engineered heart valve (TEHV)
R Nazir, A Bruyneel, C Carr, J Czernuszka
Journal of Functional Biomaterials 12 (1), 20, 2021
212021
A deep learning platform to assess drug proarrhythmia risk
R Serrano, DAM Feyen, AAN Bruyneel, AP Hnatiuk, MM Vu, PL Amatya, ...
Cell Stem Cell 30 (1), 86-95. e4, 2023
142023
Metabolic maturation media improve physiological function of human iPSC-derived cardiomyocytes. Cell Rep 32: 107925
DAM Feyen, WL McKeithan, AAN Bruyneel, S Spiering, L Hörmann, ...
132020
Designing novel BCR-ABL inhibitors for chronic myeloid leukemia with improved cardiac safety
M Pandrala, AAN Bruyneel, AP Hnatiuk, M Mercola, SV Malhotra
Journal of medicinal chemistry 65 (16), 10898-10919, 2022
112022
Reengineering ponatinib to minimize cardiovascular toxicity
AP Hnatiuk, AAN Bruyneel, D Tailor, M Pandrala, A Dheeraj, W Li, ...
Cancer research 82 (15), 2777-2791, 2022
112022
Chronic high-fat feeding affects the mesenchymal cell population expanded from adipose tissue but not cardiac atria
F Perbellini, RSM Gomes, S Vieira, D Buchanan, S Malandraki-Miller, ...
Stem Cells Translational Medicine 4 (12), 1403-1414, 2015
112015
Trilayer scaffold with cardiosphere‐derived cells for heart valve tissue engineering
Q Chen, A Bruyneel, C Carr, J Czernuszka
Journal of Biomedical Materials Research Part B: Applied Biomaterials 108 (3 …, 2020
92020
Using iPSC models to probe regulation of cardiac ion channel function
AAN Bruyneel, WL McKeithan, DAM Feyen, M Mercola
Current Cardiology Reports 20, 1-12, 2018
92018
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