Metabolic maturation media improve physiological function of human iPSC-derived cardiomyocytes DAM Feyen, WL McKeithan, AAN Bruyneel, S Spiering, L Hörmann, ... Cell reports 32 (3), 2020 | 276 | 2020 |
An automated platform for assessment of congenital and drug-induced arrhythmia with hiPSC-derived cardiomyocytes WL McKeithan, A Savchenko, MS Yu, F Cerignoli, AAN Bruyneel, JH Price, ... Frontiers in physiology 8, 766, 2017 | 81 | 2017 |
Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ C Hurtado, A Safarova, M Smith, R Chung, AAN Bruyneel, ... Scientific reports 9 (1), 10811, 2019 | 50 | 2019 |
Ambiguity in the presentation of decellularized tissue composition: the need for standardized approaches AAN Bruyneel, CA Carr Artificial organs 41 (8), 778-784, 2017 | 48 | 2017 |
Reengineering an antiarrhythmic drug using patient hiPSC cardiomyocytes to improve therapeutic potential and reduce toxicity WL McKeithan, DAM Feyen, AAN Bruyneel, KJ Okolotowicz, DA Ryan, ... Cell Stem Cell 27 (5), 813-821. e6, 2020 | 43 | 2020 |
Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy I Perea-Gil, T Seeger, AAN Bruyneel, V Termglinchan, E Monte, EW Lim, ... European Heart Journal 43 (36), 3477-3489, 2022 | 37 | 2022 |
Stem cell therapy for the heart: blind alley or magic bullet? AAN Bruyneel, A Sehgal, S Malandraki-Miller, C Carr Journal of Cardiovascular Translational Research 9, 405-418, 2016 | 33 | 2016 |
Bio-mechanical properties of novel bi-layer collagen-elastin scaffolds for heart valve tissue engineering Q Chen, A Bruyneel, C Carr, J Czernuszka Procedia Engineering 59, 247-254, 2013 | 32 | 2013 |
Physiological and pharmacological stimulation for in vitro maturation of substrate metabolism in human induced pluripotent stem cell-derived cardiomyocytes CA Lopez, HHAA Al-Siddiqi, U Purnama, S Iftekhar, AAN Bruyneel, M Kerr, ... Scientific reports 11 (1), 7802, 2021 | 30 | 2021 |
Collagen type I and hyaluronic acid based hybrid scaffolds for heart valve tissue engineering R Nazir, A Bruyneel, C Carr, J Czernuszka Biopolymers 110 (8), e23278, 2019 | 30 | 2019 |
Collagen-based scaffolds for potential application of heart valve tissue engineering Q Chen, A Bruyneel, K Clarke, C Carr, J Czernuszka J. Tissue Sci. Eng 11 (003), 1-6, 2012 | 29 | 2012 |
Will iPSC-cardiomyocytes revolutionize the discovery of drugs for heart disease? AAN Bruyneel, WL McKeithan, DAM Feyen, M Mercola Current opinion in pharmacology 42, 55-61, 2018 | 25 | 2018 |
Mechanical and degradation properties of hybrid scaffolds for tissue engineered heart valve (TEHV) R Nazir, A Bruyneel, C Carr, J Czernuszka Journal of Functional Biomaterials 12 (1), 20, 2021 | 21 | 2021 |
A deep learning platform to assess drug proarrhythmia risk R Serrano, DAM Feyen, AAN Bruyneel, AP Hnatiuk, MM Vu, PL Amatya, ... Cell Stem Cell 30 (1), 86-95. e4, 2023 | 14 | 2023 |
Metabolic maturation media improve physiological function of human iPSC-derived cardiomyocytes. Cell Rep 32: 107925 DAM Feyen, WL McKeithan, AAN Bruyneel, S Spiering, L Hörmann, ... | 13 | 2020 |
Designing novel BCR-ABL inhibitors for chronic myeloid leukemia with improved cardiac safety M Pandrala, AAN Bruyneel, AP Hnatiuk, M Mercola, SV Malhotra Journal of medicinal chemistry 65 (16), 10898-10919, 2022 | 11 | 2022 |
Reengineering ponatinib to minimize cardiovascular toxicity AP Hnatiuk, AAN Bruyneel, D Tailor, M Pandrala, A Dheeraj, W Li, ... Cancer research 82 (15), 2777-2791, 2022 | 11 | 2022 |
Chronic high-fat feeding affects the mesenchymal cell population expanded from adipose tissue but not cardiac atria F Perbellini, RSM Gomes, S Vieira, D Buchanan, S Malandraki-Miller, ... Stem Cells Translational Medicine 4 (12), 1403-1414, 2015 | 11 | 2015 |
Trilayer scaffold with cardiosphere‐derived cells for heart valve tissue engineering Q Chen, A Bruyneel, C Carr, J Czernuszka Journal of Biomedical Materials Research Part B: Applied Biomaterials 108 (3 …, 2020 | 9 | 2020 |
Using iPSC models to probe regulation of cardiac ion channel function AAN Bruyneel, WL McKeithan, DAM Feyen, M Mercola Current Cardiology Reports 20, 1-12, 2018 | 9 | 2018 |