Anti-inflammatory effects of metformin irrespective of diabetes status AR Cameron, VL Morrison, D Levin, M Mohan, C Forteath, C Beall, ... Circulation research 119 (5), 652-665, 2016 | 669 | 2016 |
Cell adhesion molecules and their roles and regulation in the immune and tumor microenvironment H Harjunpää, M Llort Asens, C Guenther, SC Fagerholm Frontiers in immunology 10, 448153, 2019 | 567 | 2019 |
Regulation of integrin activity and signalling CG Gahmberg, SC Fagerholm, SM Nurmi, T Chavakis, S Marchesan, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1790 (6), 431-444, 2009 | 305 | 2009 |
β2 integrin phosphorylation on Thr758 acts as a molecular switch to regulate 14-3-3 and filamin binding H Takala, E Nurminen, SM Nurmi, M Aatonen, T Strandin, M Takatalo, ... Blood, The Journal of the American Society of Hematology 112 (5), 1853-1862, 2008 | 189 | 2008 |
Leukocyte integrins and inflammation CG Gahmberg, L Valmu, S Fagerholm, P Kotovuori, E Ihanus, L Tian, ... Cellular and Molecular Life Sciences CMLS 54, 549-555, 1998 | 144 | 1998 |
Beta2-integrins and interacting proteins in leukocyte trafficking, immune suppression, and immunodeficiency disease SC Fagerholm, C Guenther, M Llort Asens, T Savinko, LM Uotila Frontiers in immunology 10, 254, 2019 | 133 | 2019 |
α-Chain phosphorylation of the human leukocyte CD11b/CD18 (Mac-1) integrin is pivotal for integrin activation to bind ICAMs and leukocyte extravasation SC Fagerholm, M Varis, M Stefanidakis, TJ Hilden, CG Gahmberg Blood 108 (10), 3379-3386, 2006 | 132 | 2006 |
Specific integrin α and β chain phosphorylations regulate LFA-1 activation through affinity-dependent and-independent mechanisms SC Fagerholm, TJ Hilden, SM Nurmi, CG Gahmberg The Journal of cell biology 171 (4), 705-715, 2005 | 127 | 2005 |
Phosphorylation of the cytoplasmic domain of the integrin CD18 chain by protein kinase C isoforms in leukocytes S Fagerholm, N Morrice, CG Gahmberg, P Cohen Journal of Biological Chemistry 277 (3), 1728-1738, 2002 | 119 | 2002 |
A systemic lupus erythematosus-associated R77H substitution in the CD11b chain of the Mac-1 integrin compromises leukocyte adhesion and phagocytosis M MacPherson, H San Lek, A Prescott, SC Fagerholm Journal of Biological Chemistry 286 (19), 17303-17310, 2011 | 101 | 2011 |
A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells PC Cook, H Owen, AM Deaton, JG Borger, SL Brown, T Clouaire, ... Nature communications 6 (1), 6920, 2015 | 84 | 2015 |
The CD11b-integrin (ITGAM) and systemic lupus erythematosus SC Fagerholm, M MacPherson, MJ James, C Sevier-Guy, CS Lau Lupus 22 (7), 657-663, 2013 | 80 | 2013 |
P marks the spot: site-specific integrin phosphorylation regulates molecular interactions SC Fagerholm, TJ Hilden, CG Gahmberg Trends in biochemical sciences 29 (9), 504-512, 2004 | 79 | 2004 |
β2 integrin signaling cascade in neutrophils: more than a single function P Bouti, SDS Webbers, SC Fagerholm, R Alon, M Moser, HL Matlung, ... Frontiers in Immunology 11, 619925, 2021 | 72 | 2021 |
Phosphorylation of the LFA-1 integrin β2-chain on Thr-758 leads to adhesion, Rac-1/Cdc42 activation, and stimulation of CD69 expression in human T cells SM Nurmi, M Autero, AK Raunio, CG Gahmberg, SC Fagerholm Journal of biological chemistry 282 (2), 968-975, 2007 | 71 | 2007 |
Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype VL Morrison, MJ James, K Grzes, P Cook, DG Glass, T Savinko, HS Lek, ... Nature communications 5 (1), 5359, 2014 | 66 | 2014 |
The β2 integrin–kindlin-3 interaction is essential for T-cell homing but dispensable for T-cell activation in vivo VL Morrison, M MacPherson, T Savinko, H San Lek, A Prescott, ... Blood, The Journal of the American Society of Hematology 122 (8), 1428-1436, 2013 | 63 | 2013 |
Regulation of LFA-1–dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins EY Choi, VV Orlova, SC Fagerholm, SM Nurmi, L Zhang, CM Ballantyne, ... Blood, The Journal of the American Society of Hematology 111 (7), 3607-3614, 2008 | 62 | 2008 |
The cytoskeletal association of CD11/CD18 leukocyte integrins in phorbol ester‐activated cells correlates with CD18 phosphorylation L Valmu, S Fagerholm, H Suila, CG Gahmberg European journal of immunology 29 (7), 2107-2118, 1999 | 54 | 1999 |
Lck tyrosine kinase is important for activation of the CD11a/CD18‐integrins in human T lymphocytes S Fagerholm, TJ Hilden, CG Gahmberg European journal of immunology 32 (6), 1670-1678, 2002 | 47 | 2002 |