Temozolomide resistance in glioblastoma cell lines: implication of MGMT, MMR, P-glycoprotein and CD133 expression G Perazzoli, J Prados, R Ortiz, O Caba, L Cabeza, M Berdasco, ... PloS one 10 (10), e0140131, 2015 | 203 | 2015 |
Doxorubicin-loaded nanoparticles: new advances in breast cancer therapy J Prados, C Melguizo, R Ortiz, C Vélez, P J Alvarez, J L Arias, M A Ruiz, ... Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2012 | 148 | 2012 |
Folic acid-decorated and PEGylated PLGA nanoparticles for improving the antitumour activity of 5-fluorouracil MM El-Hammadi, ÁV Delgado, C Melguizo, JC Prados, JL Arias International journal of pharmaceutics 516 (1-2), 61-70, 2017 | 133 | 2017 |
Nano-engineering of 5-fluorouracil-loaded magnetoliposomes for combined hyperthermia and chemotherapy against colon cancer B Clares, RA Biedma-Ortiz, E Sáez-Fernández, JC Prados, C Melguizo, ... European Journal of Pharmaceutics and Biopharmaceutics 85 (3), 329-338, 2013 | 112 | 2013 |
MGMT promoter methylation status and MGMT and CD133 immunohistochemical expression as prognostic markers in glioblastoma patients treated with temozolomide plus radiotherapy C Melguizo, J Prados, B González, R Ortiz, A Concha, PJ Alvarez, ... Journal of translational medicine 10, 1-11, 2012 | 97 | 2012 |
Magnetic solid lipid nanoparticles in hyperthermia against colon cancer MM de Escalona, E Sáez-Fernández, JC Prados, C Melguizo, JL Arias International journal of pharmaceutics 504 (1-2), 11-19, 2016 | 82 | 2016 |
Enhanced antitumor activity of doxorubicin in breast cancer through the use of poly (butylcyanoacrylate) nanoparticles L Cabeza, R Ortiz, JL Arias, J Prados, MA Ruiz Martinez, JM Entrena, ... International journal of nanomedicine, 1291-1306, 2015 | 79 | 2015 |
5-Fluorouracil-loaded poly(ε-caprolactone) nanoparticles combined with phage E gene therapy as a new strategy against colon cancer R Ortiz, J Prados, C Melguizo, JL Arias, MA Ruiz, PJ Álvarez, O Caba, ... International journal of nanomedicine, 95-107, 2012 | 79 | 2012 |
New gene therapy strategies for cancer treatment: a review of recent patents R Ortiz, C Melguizo, J Prados, P J Alvarez, O Caba, F Rodríguez-Serrano, ... Recent patents on anti-cancer drug discovery 7 (3), 297-312, 2012 | 76 | 2012 |
Latest in vitro and in vivo assay, clinical trials and patents in cancer treatment using curcumin: a literature review K Doello, R Ortiz, PJ Alvarez, C Melguizo, L Cabeza, J Prados Nutrition and cancer 70 (4), 569-578, 2018 | 68 | 2018 |
Regulatory systems in bone marrow for hematopoietic stem/progenitor cells mobilization and homing P Alvarez, E Carrillo, C Vélez, F Hita-Contreras, A Martínez-Amat, ... BioMed research international 2013 (1), 312656, 2013 | 67 | 2013 |
Microenvironmental modulation of decorin and lumican in temozolomide-resistant glioblastoma and neuroblastoma cancer stem-like cells C Farace, JA Oliver, C Melguizo, P Alvarez, P Bandiera, AR Rama, ... PloS one 10 (7), e0134111, 2015 | 65 | 2015 |
Improved antitumor activity and reduced toxicity of doxorubicin encapsulated in poly (ε-caprolactone) nanoparticles in lung and breast cancer treatment: An in vitro and in vivo … L Cabeza, R Ortiz, J Prados, ÁV Delgado, MJ Martín-Villena, B Clares, ... European Journal of Pharmaceutical Sciences 102, 24-34, 2017 | 63 | 2017 |
Prognostic impact of MGMT promoter methylation and MGMT and CD133 expression in colorectal adenocarcinoma JA Oliver, R Ortiz, C Melguizo, PJ Álvarez, J Gómez-Millán, J Prados BMC cancer 14, 1-11, 2014 | 53 | 2014 |
Enhanced antitumoral activity of doxorubicin against lung cancer cells using biodegradable poly (butylcyanoacrylate) nanoparticles C Melguizo, L Cabeza, J Prados, R Ortiz, O Caba, AR Rama, AV Delgado, ... Drug design, development and therapy, 6433-6444, 2015 | 51 | 2015 |
A novel nanoformulation of PLGA with high non-ionic surfactant content improves in vitro and in vivo PTX activity against lung cancer J Jiménez-López, MM El-Hammadi, R Ortiz, MD Cayero-Otero, L Cabeza, ... Pharmacological Research 141, 451-465, 2019 | 48 | 2019 |
Transcriptional profiling of peripheral blood in pancreatic adenocarcinoma patients identifies diagnostic biomarkers O Caba, J Prados, R Ortiz, C Jiménez-Luna, C Melguizo, PJ Alvarez, ... Digestive diseases and sciences 59, 2714-2720, 2014 | 44 | 2014 |
Proteomic biomarkers in body fluids associated with pancreatic cancer C Jimenez-Luna, C Torres, R Ortiz, C Dieguez, J Martinez-Galan, ... Oncotarget 9 (23), 16573, 2018 | 43 | 2018 |
DNA methylation plasticity of human adipose-derived stem cells in lineage commitment M Berdasco, C Melguizo, J Prados, A Gómez, M Alaminos, MA Pujana, ... The American journal of pathology 181 (6), 2079-2093, 2012 | 43 | 2012 |
Poly (butylcyanoacrylate) and poly (ε-caprolactone) nanoparticles loaded with 5-fluorouracil increase the cytotoxic effect of the drug in experimental colon cancer R Ortiz, L Cabeza, JL Arias, C Melguizo, PJ Álvarez, C Vélez, B Clares, ... The AAPS journal 17, 918-929, 2015 | 41 | 2015 |