Phase I study of 68Ga-HER2-nanobody for PET/CT assessment of HER2 expression in breast carcinoma M Keyaerts, C Xavier, J Heemskerk, N Devoogdt, H Everaert, C Ackaert, ... Journal of Nuclear Medicine 57 (1), 27-33, 2016 | 393 | 2016 |
Preclinical screening of anti‐HER2 nanobodies for molecular imaging of breast cancer I Vaneycken, N Devoogdt, N Van Gassen, C Vincke, C Xavier, U Wernery, ... The FASEB Journal 25 (7), 2433-2446, 2011 | 345 | 2011 |
Synthesis, preclinical validation, dosimetry, and toxicity of 68Ga-NOTA-anti-HER2 Nanobodies for iPET imaging of HER2 receptor expression in cancer C Xavier, I Vaneycken, M D’huyvetter, J Heemskerk, M Keyaerts, C Vincke, ... Journal of Nuclear Medicine 54 (5), 776-784, 2013 | 230 | 2013 |
Targeted radionuclide therapy with A 177Lu-labeled anti-HER2 nanobody M D'Huyvetter, C Vincke, C Xavier, A Aerts, N Impens, S Baatout, ... Theranostics 4 (7), 708, 2014 | 210 | 2014 |
Site-specific labeling of cysteine-tagged camelid single-domain antibody-fragments for use in molecular imaging S Massa, C Xavier, J De Vos, V Caveliers, T Lahoutte, S Muyldermans, ... Bioconjugate chemistry 25 (5), 979-988, 2014 | 168 | 2014 |
Immuno-imaging using nanobodies I Vaneycken, M D’huyvetter, S Hernot, J De Vos, C Xavier, N Devoogdt, ... Current Opinion in Biotechnology 22 (6), 877-881, 2011 | 161 | 2011 |
131I-labeled Anti-HER2 Camelid sdAb as a Theranostic Tool in Cancer Treatment M D'Huyvetter, J De Vos, C Xavier, M Pruszynski, YGJ Sterckx, S Massa, ... Clinical cancer research 23 (21), 6616-6628, 2017 | 149 | 2017 |
PET imaging of macrophage mannose receptor–expressing macrophages in tumor stroma using 18F-radiolabeled camelid single-domain antibody fragments A Blykers, S Schoonooghe, C Xavier, K D’hoe, D Laoui, M D’Huyvetter, ... Journal of Nuclear Medicine 56 (8), 1265-1271, 2015 | 148 | 2015 |
Localization, mechanism and reduction of renal retention of technetium‐99m labeled epidermal growth factor receptor‐specific nanobody in mice LO Tchouate Gainkam, V Caveliers, N Devoogdt, C Vanhove, C Xavier, ... Contrast media & molecular imaging 6 (2), 85-92, 2011 | 148 | 2011 |
Radiolabeled nanobodies as theranostic tools in targeted radionuclide therapy of cancer M D’Huyvetter, C Xavier, V Caveliers, T Lahoutte, S Muyldermans, ... Expert opinion on drug delivery 11 (12), 1939-1954, 2014 | 138 | 2014 |
Immunogenicity risk profile of nanobodies C Ackaert, N Smiejkowska, C Xavier, YGJ Sterckx, S Denies, B Stijlemans, ... Frontiers in immunology 12, 632687, 2021 | 128 | 2021 |
Sortase A‐mediated site‐specific labeling of camelid single‐domain antibody‐fragments: a versatile strategy for multiple molecular imaging modalities S Massa, N Vikani, C Betti, S Ballet, S Vanderhaegen, J Steyaert, ... Contrast media & molecular imaging 11 (5), 328-339, 2016 | 115 | 2016 |
18F-nanobody for PET imaging of HER2 overexpressing tumors C Xavier, A Blykers, I Vaneycken, M D'Huyvetter, J Heemskerk, T Lahoutte, ... Nuclear medicine and biology 43 (4), 247-252, 2016 | 107 | 2016 |
Effect of dye and conjugation chemistry on the biodistribution profile of near-infrared-labeled nanobodies as tracers for image-guided surgery P Debie, J Van Quathem, I Hansen, G Bala, S Massa, N Devoogdt, ... Molecular pharmaceutics 14 (4), 1145-1153, 2017 | 96 | 2017 |
Targeting of vascular cell adhesion molecule-1 by 18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques G Bala, A Blykers, C Xavier, B Descamps, A Broisat, C Ghezzi, D Fagret, ... European Heart Journal-Cardiovascular Imaging 17 (9), 1001-1008, 2016 | 96 | 2016 |
Development of 177Lu‐nanobodies for radioimmunotherapy of HER2‐positive breast cancer: evaluation of different bifunctional chelators M D'Huyvetter, A Aerts, C Xavier, I Vaneycken, N Devoogdt, M Gijs, ... Contrast Media & Molecular Imaging 7 (2), 254-264, 2012 | 95 | 2012 |
Heptyl α‐D‐Mannosides Grafted on a β‐Cyclodextrin Core To Interfere with Escherichia coli Adhesion: An In Vivo Multivalent Effect J Bouckaert, Z Li, C Xavier, M Almant, V Caveliers, T Lahoutte, SD Weeks, ... Chemistry–A European Journal 19 (24), 7847-7855, 2013 | 84 | 2013 |
Clinical Translation of [68Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages C Xavier, A Blykers, D Laoui, E Bolli, I Vaneyken, J Bridoux, H Baudhuin, ... Molecular imaging and biology 21, 898-906, 2019 | 82 | 2019 |
Theranostic radiolabeled anti-CD20 sdAb for targeted radionuclide therapy of non-Hodgkin lymphoma A Krasniqi, M D'Huyvetter, C Xavier, K Van der Jeught, S Muyldermans, ... Molecular cancer therapeutics 16 (12), 2828-2839, 2017 | 75 | 2017 |
Melanoma targeting with α-melanocyte stimulating hormone analogs labeled with fac-[99mTc(CO)3]+: effect of cyclization on tumor-seeking properties PD Raposinho, C Xavier, JDG Correia, S Falcao, P Gomes, I Santos JBIC Journal of Biological Inorganic Chemistry 13, 449-459, 2008 | 74 | 2008 |